Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Gut Microbiota May Affect a Variability of Tacrolimus Trough Levels in Kidney Transplant Recipients
J. Kim¹, H. Cho², J. Park³, M. Kwak⁴, B. Kim⁴, J. Lee⁵, D. Kim¹, B. Kim⁶, Y. Kim¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Chungbuk National University Hospital, Cheongju, Korea, Republic of, ³Kangwon National University Hospital, Chuncheon, Korea, Republic of, ⁴Chunlab Inc., Seoul, Korea, Republic of, ⁵Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Hallym University, Chuncheon, Korea, Republic of
*Purpose: The gut microbiota alters expression of drug-metabolizing enzymes and transporters, and consequently affects therapeutic dose and response of medicines. We aimed to investigate the…
2019 American Transplant Congress
Transplant Regimen Adherence For Kidney Recipients By Engaging Information Technologies: The Take It Trial
D. P. Ladner¹, M. S. Wolf²
¹Surgery, Northwestern Medicine, Chicago, IL, ²General Internal Medicine, Northwestern University, Chicago, IL
*Purpose: Several studies report a high prevalence of inadequate adherence to prescribed (Rx) immunosuppressive (IS) medication regimens among kidney transplant (KT) recipients, yet few interventions…
2019 American Transplant Congress
The Influential Yet Highly Variable Role of Biopsy Findings on Kidney Offer Acceptance Decisions: An Organ Offer Simulation Study
D. Stewart¹, J. Rosendale¹, H. McGehee¹, I. Hall², G. Gupta³, K. Reddy⁴, B. Kasiske⁵, K. Andreoni⁶, D. Klassen¹
¹UNOS, Richmond, VA, ²Univ of Utah, Salt Lake City, UT, ³VCU, Richmond, VA, ⁴Mayo, Phoenix, AZ, ⁵HCMC, Minneapolis, MN, ⁶Univ of Florida, Gainesville, FL
*Purpose: The use of procurement biopsies (Bx) to assess kidney quality is controversial. ‘Biopsy findings’ is an often cited discard reason, yet the association between…
2019 American Transplant Congress
Impact of Donor Hepatitis C Virus Infection on Kidney Transplant Outcomes in the Direct Acting Antiretroviral Era: Time to Revise the KDPI?
R. M. Cannon, E. G. Davis, L. Mackelaite, H. Dave, M. Eng, C. M. Jones
University of Louisville, Louisville, KY
*Purpose: The kidney donor risk index (KDRI), upon which the kidney donor profile index (KDPI) used for renal allocation is based, was derived before the…
2019 American Transplant Congress
Enhanced Recovery after Surgery Protocols in Kidney Transplantation: Time to Change Practice?
A. M. Elsabbagh, I. Ghoneim, A. Moiz, D. Mckenney, M. A. Zawaideh
St. Vincent Abdominal Transplant Center, St. Vincent Hospital, Indianapolis, IN
*Purpose: Enhanced recovery after surgery (ERAS) is a multi-modal perioperative care pathway designed to facilitate early recovery after major surgery by maintaining preoperative body composition…
2019 American Transplant Congress
Early Outcomes Comparing Two Steroid-Avoidance Protocols in Pediatric Renal Transplantation
D. Puliyanda¹, H. Pizzo¹, N. Rodig², M. Somers²
¹Cedars-Sinai Med Ctr, Los Angeles, CA, ²Pediatric Nephrology, Boston Childrens Hospital, Boston, MA
*Purpose: Steroid-avoidance in pediatric kidney transplants (txs) was found effective and safe with daclizumab induction. Upon daclizumab’s discontinuation, lymphocyte-depleting agents became used in this setting,…
2019 American Transplant Congress
Risk Factors for Recurrence and Predictors of Response in Kidney Transplant Recipients with Primary FSGS
A. Uffing¹, T. TANGO-consortium², P. Cravedi³, L. V. Riella¹
¹Renal Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²NA, Boston, MA, ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently recurs after kidney transplantation. Several circulating factors have been proposed to cause recurrence…
2019 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies Improve Risk Stratification for Kidney Allograft Outcomes at the Time of Transplantation
C. Lefaucheur¹, D. Viglietti¹, Y. Bouatou¹, A. Philippe², D. Pievani¹, O. Aubert¹, D. Glotz¹, C. Legendre¹, A. Loupy¹, D. Dragun²
¹Paris Translational Research Center for Organ Transplantation, Paris, France, ²Medical Faculty of the Charité Berlin, Berlin, Germany
*Purpose: Current state-of-the-art pre-transplant risk stratification relies on the HLA system. Non-HLA agonistic angiotensin II type 1 receptor antibodies (AT1R-Ab) have been associated with allograft…
2019 American Transplant Congress
Non-adherence With Diet And Dialysis Prescription: Predictors Of Non-adherence Post-transplant?
A. Padiyar¹, A. Agrawal¹, D. Hricik¹, P. Bate², J. Rockwell², A. Eliason², N. Sarabu¹, A. Jittirat¹, K. Yadav², E. Sanchez², M. Debroy², V. Humphreville², J. Rabets², A. Palanisamy², K. Chavin²
¹Medicine, Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, ²Transplant Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Perceived non-adherence with diet and dialysis prescription prior to transplant may be seen as a risk for non-adherence with immunosuppression post-transplant. The importance of…
2019 American Transplant Congress
A Comprehensive and Updated Analysis of Combined Heart-Kidney Transplants Utilizing the United Network for Organ Sharing Database
V. M. Lim¹, N. Khurmi¹, W. R. Hewitt, Jr.², A. K. Mathur², O. E. Pajaro³, D. E. Jaroszewski³, B. D. Gaitan¹
¹Anesthesiology, Mayo Clinic Arizona, Phoenix, AZ, ²Transplantation Surgery, Mayo Clinic Arizona, Phoenix, AZ, ³Cardiovascular and Thoracic Surgery, Mayo Clinic Arizona, Phoenix, AZ
*Purpose: Analysis of combined heart-kidney transplants (HKTx) reveals equivalent or improved patient survival and reduced allograft rejection rates as compared to single-organ transplants. The rate…