Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Obinutuzumab in Kidney Transplantation: Effect on B-cell Counts and Crossmatch Tests
M. M. Nasrallah¹, M. Elalfy¹, Y. Elmesseery², I. Amer¹, P. Malvezzi³, L. Rostaing⁴
¹Misr International Hospital, Cairo, Egypt, ²Misr International Hospital, Caire, Egypt, ³CHU Grenoble-Alpes, Grenoble, France, ⁴Service de Néphrologie, CHU Grenoble-Alpes, Grenoble, France
*Purpose: Resistance to the action of rituximab (RTX), has been documented in several diseases. More recently, obinutuzumab (OBZ) has shown promise where RTX has failed…
2022 American Transplant Congress
The Effect of Late-Onset Cytomegalovirus Infection on the Outcome of Renal Allograft in Patients with Delayed Graft Function
M. Rahimi Shahmirzadi¹, M. Silverman¹, L. Gunaratnam², A. Jevnikar², A. A. House², S. Hosseini-Moghaddam³
¹Infectious Diseases Care Program, St. Joseph's Health Care London, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada, ³St. Joseph's Health Care London, London, ON, Canada
*Purpose: Delayed graft function (DGF) has been reported to increase the risk of renal allograft loss. The role of late-onset Cytomegalovirus infection in the association…
2022 American Transplant Congress
Knowledge, Attitude, and Practices Regarding Covid-19 Among Solid Organ Transplant Patients at a Transplant Center in the United States: A Cross-Sectional Study
L. Wang, H. Oduor, M. Abualfoul, P. Acharya, M. Pagadala
Methodist Dallas Medical Center, Dallas, TX
*Purpose: To evaluate the knowledge, attitude, and practices (KAP) of patients who have undergone kidney and/or liver solid organ transplants (SOTs) during the COVID-19 pandemic.*Methods:…
2022 American Transplant Congress
Very Low Frequency of Pathological Findings in One-Year Protocol Biopsies of Low-Risk Kidney Transplant Recipients – Results from the Nordic Protocol Biopsy Study
I. Helanterä¹, C. Dörje², F. Ortiz³, A. Varberg Reisæter², C. Hammarstrøm², J. Lauronen⁴, A. Räisänen-Sokolowski⁵, A. J. Haugen⁶, M. Lempinen¹, A. Åsberg², G. Mjøen²
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland, ²Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, ³Nephrology, Helsinki University Hospital, Helsinki, Finland, ⁴Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland, ⁵Department of Pathology, Helsinki University Hospital, Helsinki, Finland, ⁶Medical Department, Bærum Hospital, Bærum, Norway
*Purpose: The clinical usefulness of kidney graft protocol biopsies have been debated. We studied the frequency of borderline and T-cell-mediated rejection (TCMR) in one-year protocol…
2022 American Transplant Congress
Low T Cell Responsiveness in the Early Phase Of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients
M. Cremoni¹, S. Cuozzo¹, E. Martinuzzi², S. Barbosa², N. Ben Hassen¹, F. Massa³, E. Demonchy⁴, M. Durand⁵, O. Thaunat⁶, V. Esnault¹, M. Lequintrec⁷, S. Caillard⁸, N. Glaichenhaus², A. Sicard¹
¹Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire de Nice, Nice, France, ²CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France, ³Université Côte d'Azur, Laboratoire de Physio-Médecine Moléculaire, Nice, France, ⁴Service d'Infectiologie, Centre Hospitalier Universitaire de Nice, Nice, France, ⁵Service d'Urologie, Centre Hospitalier Universitaire de Nice, Nice, France, ⁶Service de Transplantation rénale, Néphrologie et Immunologie clinique, Hôpital Edouard Herriot, Hospices civils de Lyon, Lyon, France, ⁷Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire Lapeyronie, Montpellier, France, ⁸Service de Néphrologie et Transplantation, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France
*Purpose: Kidney transplant (KT) recipients are more prone to developing life-threatening forms of COVID-19 than the general population. Little is known about the immunological mechanisms…
2022 American Transplant Congress
High Incidence Of Anti-HLA DSA And Late Allograft Dysfunction In Solid Organ Transplant Recipients Hospitalized With Covid-19
J. T. Killian, S. Roman Soto, V. Hauptfeld-Dolejsek, E. B. Levitan, P. M. Porrett, V. Kumar, F. E. Lund, J. A. Houp
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Solid organ transplant (SOT) recipients admitted for COVID-19 commonly experience immunosuppression reduction and acute allograft dysfunction. Given the number of SOT patients hospitalized for…
2022 American Transplant Congress
Use of New 2021 CKD-EPI as an Endpoint in Transplant Trials May Significantly Influence Observations
E. Yanqui¹, H. Hames¹, T. Shi², A. R. Shields¹, E. S. Woodle¹, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²CCHMC, Cincinnati, OH
*Purpose: GFR equations have recently been modified primarily to avoid disadvantaging black populations. The purpose of this study was to evaluate renal function and the…
2022 American Transplant Congress
Robotic Partial Nephrectomy in Transplanted Kidney
A. Kaviani, M. Abou Zeinab, M. Noble, Y. Lin, A. Wee, J. Kaouk, M. Eltemamy
Cleveland Clinic, Cleveland, OH
*Purpose: To present, in a video format, the technical considerations for performing a robotic partial nephrectomy in a transplanted kidney.*Methods: Two patients underwent this procedure.…
2022 American Transplant Congress
Infiltrating CD8+ Cytotoxic T Cells Are Converted to a Regulatory Phenotype in Accepted Kidney Allografts
T. Yokose¹, E. S. Szuter¹, M. T. Guinn¹, J. Ge², I. Rosales³, M. Ford⁴, P. S. Russell¹, A. G. Cuenca², J. C. Madsen¹, R. B. Colvin¹, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Boston Children's Hospital, Boston, MA, ³Department of Pathology, Massachusetts General Hospital, Boston, MA, ⁴Department of Surgery, Emory University, Atlanta, GA
*Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations (i.e. DBA/2J to C57BL/6 (B6)) without any immunosuppressive drug treatment. We have…
2022 American Transplant Congress
Palliative Care for the Patients with Failing Kidney Allograft: Kraft Survey
N. Murakami¹, S. Gelfand¹, A. J. Reich¹, R. Leiter², J. Lakin², J. T. Adler³, E. Lu⁴, S. Ong⁵, B. P. Concepcion⁶, N. Singh⁷, H. Murad⁸, P. Anand⁹, S. Ramer¹⁰, D. Dadhania¹¹, K. Lentine¹², T. Alhamad¹³
¹Brigham and Women's Hospital, Boston, MA, ²Dana-Farber Cancer Institute, Boston, MA, ³University of Texas Austin, Austin, TX, ⁴Icahn School of Mount Sinai, New York, NY, ⁵Universiy of Alabama at Birmingham, Birmingham, AL, ⁶Vanderbilt University Medical Center, Nashville, TN, ⁷John C. McDonald Regional Transplant Center, Shreveport, LA, ⁸Washington University in St Louis, Chesterfield, MO, ⁹Medical University of South Carolina, Lancaster, SC, ¹⁰Weil Cornell Medicine, New York, NY, ¹¹Weill Cornell Medicine - NYPH, New York, NY, ¹²Saint Louis University, St. Louis, MO, ¹³Washington University School of Medicine at St. Louis, Saint Louis, MO
*Purpose: Care of patients with failing kidney allograft can be challenging with discordant expectations between clinicians and patients. These patients often suffer from multiple morbidities,…