Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Protocol Cidofovir for Refractory Polyomavirus Associated Nephropathy in Kidney Transplant Recipients
J. Clark, A. Haririan
University of Maryland Medical Center, Baltimore, MD
*Purpose: Dose-limiting nephrotoxicity has historically precluded the use of cidofovir for polyomavirus associated nephropathy (PVAN). With incidence of BK viremia in kidney transplant recipients increasing…
2019 American Transplant Congress
Evaluating Potentially Inappropriate Prescribing in Older Kidney Transplant Recipients
L. DeVietro¹, B. Richardson², E. A. Cohen³, A. H. Toledo⁴, E. Marin⁵, K. R. Szempruch⁶
¹University of St. Joseph School of Pharmacy, Hartford, CT, ²University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, ³Pharmacy, Yale New Haven Hospital, New Haven, CT, ⁴Surgery-Transplant, University of North Carolina Medical Center, Chapel Hill, NC, ⁵Nephrology, Yale New Haven Hospital, New Haven, CT, ⁶Pharmacy, University of North Carolina Medical Center, Chapel Hill, NC
*Purpose: While the Beers criteria (BC) and STOPP criteria (SC) have been validated in several patient populations to reduce medication use leading to adverse drug…
2019 American Transplant Congress
Gene Expression Profiles in CD8+ T Cells in Chronic Antibody-Mediated Rejection (CAMR) of Kidney Transplantation
P. Pontrelli¹, F. Rascio², M. Accetturo¹, G. Castellano¹, S. Simone¹, G. Stallone², L. Gesualdo¹, G. Grandaliano²
¹Department of Emergency, and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, Italy, ²Dept. of Surgical and Medical Sciences, Nephrology Unit, University of Foggia, Foggia, Italy
*Purpose: CAMR is the main cause of chronic graft injury and subsequent graft loss. Most of the studies on the subject focused their attention to…
2019 American Transplant Congress
How Much Does Graft Function Cost Us? A Financial Analysis of Delayed Graft Function in Kidney Transplant Recipients
A. Yaldo, I. Bajjoka, C. Crombez, M. Abouljoud
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Kidney transplant recipients (KTR) who receive dialysis post-transplant experience worse outcomes during the first year post-transplant. Whether KTR discharged with elevated levels of serum…
2019 American Transplant Congress
Listing Practices and Graft Utilization Lag behind Supply of Hepatitis C Positive Deceased Donors for Liver and Kidney Transplant
C. E. Kling¹, J. D. Perkins², S. W. Biggins³, C. Johnson⁴, A. P. Limaye⁵, L. Sibulesky¹
¹Division of Transplant Surgery, University of Washington Medical Center, Seattle, WA, ²Division of Transplant Surgery and Clinical and Bio-Analytics Transplant Laboratory, University of Washington Medical Center, Seattle, WA, ³Divisions of Gastroenterology and Hepatology and Center for Liver Investigation Fostering DiscovEry, University of Washington Medical Center, Seattle, WA, ⁴Division of Nephrology, University of Washington Medical Center, Seattle, WA, ⁵Division of Infectious Disease, University of Washington Medical Center, Seattle, WA
*Purpose: The opioid epidemic resulted in increasing incidence of hepatitis C (HCV) in the general population and more deceased organ donors with HCV in the…
2019 American Transplant Congress
Incidence and Mortality of Renal Cell Carcinoma after Kidney Transplantation: A Meta-Analysis
A. Chewcharat¹, C. Thongprayoon², B. Boonpheng³, A. Torres-Ortiz⁴, M. A Mao², N. J Khoury⁵, W. Cheungpasitporn⁴
¹Harvard T.H. Chan, Boston, MA, ²Mayo Clinic, Rochester, MN, ³East Tennessee State University, Johnson City, TN, ⁴University of Mississippi Medical Center, Jackson, MS, ⁵Henry Ford Hospital, Detroit, MI
*Purpose: The incidence and mortality of renal cell carcinoma (RCC) after kidney transplantation (KTx) remain unclear. This study's aims were 1) to investigate the pooled…
2019 American Transplant Congress
Chimeric Allografts Induced by Stem Cell Mobilizing Agents in a Mouse Model of Kidney Transplantation: Role of CD133 Stem Cells
J. Zhou, l. Qi, A. Ahmadi, R. Wesson, A. Cameron, J. Burdick, Z. Sun
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: It has been reported that a stem cell mobilizing therapy using a combination of AMD3100 and low dose FK506 (AF) enabled immunosuppressive-free long-term kidney…
2019 American Transplant Congress
Room for Optimism; Improvement in Long-Term Patient and Graft Survival of Kidney Transplants in the United States over the past Three Decades
C. Wu, A. Rana, N. Galvan, C. O'Mahony, J. Goss, B. Murthy
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Previous studies indicated that the short-term (1 year) allograft survival of kidney transplants has improved significantly over the years. However, less is known about…
2019 American Transplant Congress
Anti-HLA IgM Antibodies Are Reduced in Highly-HLA Sensitized Patients Transplanted after Imlifidase (IdeS) Treatment
X. Zhang¹, S. Jordan²
¹HLA and Immunogenetics Laboratory, Comprehensive Transplant Center, Cedars-Sinai Health System, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Health System, Los Angeles, CA
*Purpose: Immunoglobulin-degrading enzyme from Streptococcus pyogenes (IdeS, Imlifidase) has been used to reduce antibody levels to promote transplant of highly sensitized patients. In vitro experiments…
2019 American Transplant Congress
Normothermic Regional Perfusion of Kidneys: A Single Non-Retrieval Centre Experience
R. Pearson, C. Geddes, M. Clancy, J. Asher
Renal Transplant, Queen Elizabeth University Hospital, Glasgow, Glasgow, United Kingdom
*Purpose: With the aim of safely expanding the pool of usable donors from circulatory death (DCD) there is increasing interest in normothermic regional (NRP) perfusion…