Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Standardizing Blood Pressure Measurement across 17 Pediatric Transplant Centers: The Improving Renal Outcomes Collaborative
M. E. Seifert¹, R. Garro², R. P. George², G. Barletta³, C. W. Belsha⁴, A. Chaudhuri⁵, J. W. Goebel⁶, L. Wickman⁷, D. Matossian⁸, J. Misurac⁹, C. Nailescu¹⁰, C. R. Nguyen¹¹, M. Pearl¹², A. Pollack¹³, C. S. Pruette¹⁴, P. Singer¹⁵, P. S. Verghese¹⁶, B. A. Warady¹⁷, D. S. Dahale¹⁸, D. K. Hooper¹⁸
¹University of Alabama, Birmingham, AL, ²Emory University, Atlanta, GA, ³Phoenix Children's Hospital, Phoenix, AZ, ⁴Saint Louis University, St. Louis, MO, ⁵Stanford University, Stanford, CA, ⁶Children's Hospital Colorado, Aurora, CO, ⁷Michigan Medicine, Ann Arbor, MI, ⁸Lurie Children's Hospital, Chicago, IL, ⁹University of Iowa, Iowa City, IA, ¹⁰Riley Hospital For Children, Indianapolis, IN, ¹¹Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ¹²UCLA Mattel Children’s Hospital, Los Angeles, CA, ¹³Seattle Children's Hospital, Seattle, WA, ¹⁴Johns Hopkins University, Baltimore, MD, ¹⁵Cohen Children's Medical Center, New Hyde Park, NY, ¹⁶University of Minnesota, Minneapolis, MN, ¹⁷Children's Mercy Kansas City, Kansas City, MO, ¹⁸Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: We report efforts from the Improving Renal Outcomes Collaborative (IROC) to standardize appropriate BP measurement across 17 pediatric kidney transplant centers.*Methods: 17 centers participated…
2019 American Transplant Congress
Actions Speak Louder Than Labs – The Impact of Dialysis Compliance on Posttransplant Outcomes
D. Sawinski¹, H. Lindner², J. Schults³, J. Locke⁴, P. Reese¹
¹Hospital of the U of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Children's Hospital of Pennsylvania, Philadelphia, PA, ⁴University of Alabama at Birmingham, Birmingham, AL
*Purpose: Non-adherence is a modifable risk factor for poor posttransplant outcomes. While the factors contributing to posttransplant non-adherence are complex, noncompliance with the dialysis prescription…
2019 American Transplant Congress
Higher Level of Social Support is Associated with Higher Likelihood of Pursuit of Living Donor Kidney Transplant (LDKT)
T. Ahmed¹, S. Dano¹, Z. Zhou¹, I. Unarain¹, M. Saqib¹, V. Li¹, Y. Khoo¹, M. Novak², I. Mucsi¹
¹Multi-Organ Transplant Program and Division of Nephrology, University Health Network, Toronto, ON, Canada, ²Centre for Mental Health, University Health Network, Toronto, ON, Canada
*Purpose: LDKT is the optimal treatment for many patients with End Stage Kidney Disease (ESKD) , offering better clinical outcomes and quality of life. Studies…
2019 American Transplant Congress
Tissue Resident Memory T Cells in Murine Renal Transplantation
K. Abou-Daya, D. Zhao, R. Tieu, A. Williams, M. Oberbarnscheidt, F. Lakkis
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: The newly identified tissue resident subset of memory T cells (TRM) provides immune surveillance in the tissue and first response against infections. They are…
2019 American Transplant Congress
LCP-Tacrolimus (LCPT; Envarsus XR) Dosing Considerations in De Novo Kidney Transplant Recipients
D. Cibrik¹, P. West-Thielke², S. J. Patel³, D. R. Stevens⁴, U. Meier-Kriesche⁴
¹University of Kansas Medical Center, Kansas City, KS, ²University of Illinois Hospital and Health Sciences System, Chicago, Chicago, IL, ³Veloxis Pharmaceuticals, Cary, NC, ⁴Veloxis Pharmaceuticals Inc., Cary, NC
*Purpose: Different initial dosing strategies were studied in Phase II/Phase III trials evaluating the pharmacokinetics, safety, and efficacy of LCPT in de novo kidney transplantation.…
2019 American Transplant Congress
Age-Related Effects on Thymic Output and Homeostatic T Cell Expansion Following Depletional Induction
H. Xu, H. Lee, A. Kirk
Surgery, Duke University, Durham, NC
*Purpose: Alemtuzumab induction leads to profound T cell depletion followed by a prolonged period of repopulation. Repopulation is thought to be influenced both by thymic…
2019 American Transplant Congress
Dialysis Facility Provider Transplant Knowledge after a Randomized Multilevel Intervention to Increase Kidney Transplant Referral and Evaluation in the Southeast
K. Maroney¹, R. Hamoda¹, L. McPherson¹, A. Cruz², S. Pastan¹, L. Plantinga¹, S. Paul¹, M. Ellis³, D. DuBay⁴, A. Reeves-Daniel⁵, R. Detwiler⁶, E. Hartmann⁷, H. Jones⁸, B. Thrasher⁹, C. Zayas¹⁰, L. Mulloy¹⁰, S. Wright¹¹, R. Patzer¹
¹Emory University, Atlanta, GA, ²IPRO Network of the South Atlantic, Raleigh, NC, ³Duke University, Durham, NC, ⁴Medical University of South Carolina, Charleston, SC, ⁵Wake Forest Health Transplant Center, Winston-Salem, NC, ⁶UNC Center for Transplantation, Chapel Hill, NC, ⁷Piedmont Transplant Institute, Atlanta, GA, ⁸Vidant Medical Center Transplant Services, Greenville, NC, ⁹Carolinas Transplant Center, Charlotte, NC, ¹⁰Augusta University, Augusta, GA, ¹¹IPRO Network of the South Atlantic, Morrisville, NC
*Purpose: Dialysis facility provider kidney transplantation (KTx) knowledge influences patient transplant access. The Reducing Disparities in Access to kidNey Transplantation (RaDIANT) Regional Study is a…
2019 American Transplant Congress
Replication of Diagnostic Biomarkers Using Orthogonal State-of-the-Art Technologies
M. Cassidy, B. Dooley, A. Verma, H. Yang, T. Muthukumar, R. Ding, C. Li, C. Snopkowski, B. Botticelli, S. Albakry, E. Edusei, M. Lubetzky, D. Dadhania, J. Lee, O. Elemento, M. Suthanthiran
WCM, New York, NY
*Purpose: The failure to reproduce scientific findings (McNutt M. Science 2014;343:229, Baker M. Nature 2016;53:452) has brought to the forefront the need for replication studies…
2019 American Transplant Congress
Distinct Delayed Classical Complement Pathway Activation Highlights Transition of Ischemic Acute Kidney Injury to Chronic Kidney Disease with Interstitial Fibrosis/Tubular Atrophy
S. Kumar, S. Jordan
Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: Ischemia reperfusion Injury (IRI)-induced AKI of the renal allograft frequently leads to delayed graft function (DGF). Patients with DGF suffer from prolonged hospitalization with…
2019 American Transplant Congress
Impact of IgG Subclass and C1q Binding Donor-Specific HLA Antibodies on Antibody Mediated Rejection in Kidney Transplant Recipients
H. Lee¹, J. Ryu¹, S. Yun¹, T. Ban², E. Ko², C. Yang², E. Oh¹
¹Department of Laboratory Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ²Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: Donor specific HLA antibody (DSA) is a leading cause of antibody mediated rejection (AMR) and graft loss in kidney transplants. It is known that…