Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Comparison of Isolated Transplant Glomerulopathy with Chronic Antibody-Mediated Rejection in Regards to Endothelial-to-Mesenchymal Transition and Graft Survival
B. H. Ozdemir¹, F. N. Ozdemir², G. Moray³, M. Haberal³
¹Pathology, Baskent University, Ankara, Turkey, ²Nephrology, Baskent University, Ankara, Turkey, ³Transplantation, Baskent University, Ankara, Turkey
*Purpose: Transplant glomerulopathy (TG) has been proposed to be a component of chronic antibody-mediated rejection (CAMR). However, a substantial number of patients with TG do…
2019 American Transplant Congress
Increase in Proinflammatory CD14++CD16+ Monocytes in Samples from Aspiration Cytology Compared with Peripheral Blood in Kidney Transplant Patients with Borderline Rejection
T. Vazquez-Sanchez¹, A. Caballero-Gonzalez², E. Sola¹, P. Ruiz-Esteban¹, E. Marques¹, J. Alonso-Titos¹, E. Palma¹, C. Jironda¹, M. Cabello¹, V. Lopez¹, P. Hidalgo¹, M. Leon¹, D. Hernandez¹
¹Nephrology, Hospital Regional Universitario de Málaga, Universidad de Málaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain, ²Immunology, Hospital Regional Universitario de Málaga, Universidad de Málaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain
*Purpose: Monocytes comprise a heterogeneous population divided according to the membrane expression level of their molecules. One of these populations is the CD14++CD16+, which presents…
2019 American Transplant Congress
Evaluation of Delayed Renal Allograft Function after DCD with New Biomarkers in Donor Blood
X. Zheng
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
*Purpose: To explore the relationship between new biomarkers in donor blood and delayed graft function (DGF) after DCD kidney transplantation, and to evaluate the clinical…
2019 American Transplant Congress
A2 To B Kidney Transplants Under Kidney Allocation System: A Prospective Study Of Anti A Titers And Correlation With Outcomes
H. Schaefer, I. Feurer, S. Rega, R. Forbes, D. Shaffer
Vanderbilt University, Nashville, TN
*Purpose: The UNOS KAS system incorporates A2 to B deceased donor kidney transplants (DDKTx) to improve access and reduce disparities in wait times for B…
2019 American Transplant Congress
Race-Sex Effects on Immune Response Potential during Tacrolimus Minimization Therapy in Stable Renal Allograft Recipients
K. Tornatore¹, K. Attwood², R. Venuto³, H. Minderman⁴
¹University at Buffalo; School of Pharmacy, Buffalo, NY, ²Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, ³University at Buffalo; School of Medicine: Nephrology, Buffalo, NY, ⁴Flow & Image Cytometry, Roswell Park Comprehensive Cancer Center, Buffalo, NY
*Purpose: African American renal transplant recipients (RTR) exhibit more immunoreactivity to allografts which may contribute to chronic rejection. This study investigated race-sex influences on ex…
2019 American Transplant Congress
A Retrospective Observational Analysis of Tacrolimus Metabolism Rate: No Evidence for Impact on Renal Function
A. J. Hughes, J. E. Kimpton, I. MacPhee
Renal Medicine and Transplantation, St George’s University Hospitals NHS Foundation Trust, London, United Kingdom
*Purpose: A previous publication found that fast metabolisers of tacrolimus had inferior renal function compared to slow metabolisers in a Caucasian population (Thölking et al.,…
2019 American Transplant Congress
Impact of HLA-DR Matching on HLA-DQ Matching Status and the Development of Anti-HLA-DQ De Novo DSA under Calcineurin Inhibitor or Belatacept Immunosuppression
V. Jucaud¹, H. Gebel², R. Bray², M. Polinsky³, M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Emory University, Atlanta, GA, ³Bristol-Myers Squibb, Princeton, NJ
*Purpose: De novo donor-specific HLA antibodies (dnDSA) that develop after kidney transplantation target more frequently allo-HLA-DQ antigens in comparison to other allo-HLA antigens. Yet, organ…
2019 American Transplant Congress
Estrogen Mediated Protection in Renal Ischemia Reperfusion Injury (IRI) is Extrinsic to the Kidney
D. D. Aufhauser¹, S. J. Concors¹, P. T. Hernandez¹, Z. Wang¹, L. Krumeich¹, D. R. Murken¹, G. Ge¹, W. W. Hancock², M. H. Levine¹
¹Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ²Pathology, Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: IRI causes morbidity in renal transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required so that strategies…
2019 American Transplant Congress
Torque Teno Virus is a Prognostic Biomarker for Acute Biopsy-Proven Alloreactivity in Kidney Transplants
K. Doberer
Dpt. of Internal Medicine III, Div. of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria
*Purpose: Drug-induced immunosuppression in kidney transplantation is crucial to prevent allograft rejection, but increases risk for infectious, cardiovascular and malignant disease. Tailoring of immunosuppressive drug…
2019 American Transplant Congress
Unsuccessful Resuscitative Thoracotomy Patients Are Potential Kidney Donors
K. Prins¹, H. B. Moore¹, A. Sauaia¹, R. Choudhury¹, R. C. McIntyre¹, A. Cralley², S. Urban¹, E. E. Moore², E. A. Pomfret¹, T. L. Nydam¹
¹University of Colorado Hospital, Aurora, CO, ²Denver Health Medical Center, Denver, CO
*Purpose: Renal transplantation remains the most effective therapy in patients with end-stage renal disease, offering exceptional survival benefits and quality of life improvement. However, a…