Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Dosing Requirements Of Astagraf Xl In African American Kidney Transplant Recipients Converted From Twice-daily Tacrolimus (aaaktrs)
J. N. Fleming, M. A. Posadas-Salas, D. J. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: Pharmacokinetics from clinical studies demonstrated similar drug exposure (AUC) and correlation between trough (C0) and AUC between tacrolimus IR and Astagraf XL, which led…
2019 American Transplant Congress
Outcomes in Kidney Transplant Recipients after Conversion from Tacrolimus to Belatacept-Based Regimens
H. Underwood, N. Lange, J. Hedvat, C. Brennan, D. Tsapepas, K. King, S. Husain, D. Salerno, S. Patel, S. Mohan, R. Crew
Columbia University Irving Medical Center, New York, NY
*Purpose: Immunosuppressive strategies for belatacept are variable and associated outcomes have not been well described. We examined outcomes among kidney transplant (KT) recipients converted from…
2019 American Transplant Congress
Long Term Cold Ischemia Time in Kidney Transplantation. The Role of Hypothermic Machine Perfusion
G. ADANI¹, U. Baccarani¹, P. Tulissi², C. Vallone², A. Risaliti¹
¹General Surgery and Transplantation, Academic Hospital P. le S.M. della Misericordia, 33100 Udine, Italy, Udine, Italy, ²Nephrology, Dialysis and Kidney Transplantation, Academic Hospital P. le S.M. della Misericordia, 33100 Udine, Italy, Udine, Italy
*Purpose: Hypothermic machine perfusion (HMP) of deceased donor kidneys is associated with a better outcome than static cold storage (SCS). Aim of this prospective study…
2019 American Transplant Congress
Broadly Profiling the Activation Status of Circulating Immune Cells in Chronic Active Antibody Mediated Rejetion Reveals Increased CD38 and CD16 Expression on Monocytes and NK Cells
K. Sablik, N. Litjens, M. Klepper, M. Betjes
Erasmus MC, Rotterdam, Netherlands
*Purpose: Chronic-active antibody mediated rejection (c-aABMR) contributes significantly to late renal allograft failure. Non-invasive biomarkers of c-aABMR are currently not available but could be valuable…
2019 American Transplant Congress
Kidney Donor Profile Index Significantly Correlates With Reperfusion Biopsy Findings
A. Perez-Gutierrez¹, P. Witkowski¹, J. Fung¹, D. N. Danz², R. Cummings¹, A. Chang³
¹Transplantation Institute, University of Chicago Medicine, Chicago, IL, ²Economics, University of Pittsburgh, Pittsburgh, PA, ³Pathology, University of Chicago Medicine, Chicago, IL
*Purpose: The kidney donor profile index (KDPI) includes donor factors that are associated with graft survival, and estimates the quality of the kidney graft. Suboptimal…
2019 American Transplant Congress
Aborted Live Donor Organ Recovery Procedures in the United States
M. Henderson, M. Waldram, A. Thomas, N. Desai, S. Ottman, J. Garonzik Wang, A. Massie, D. Segev, J. Bannon, F. Al Ammary, D. Brennan
Johns Hopkins, Baltimore, MD
*Purpose: Although live organ donation is a carefully and meticulously planned surgical procedure, live donor organ recovery procedures are occasionally aborted. These include procedures which…
2019 American Transplant Congress
Kidney Transplantation in Older Recipients with HLA-DR Mismatch: Impact of Induction Type on Outcomes
K. K. Sureshkumar¹, N. L. Thai², B. Chopra¹
¹Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA, ²Abdominal Transplantation, Allegheny General Hospital, Pittsburgh, PA
*Purpose: In kidney transplantation, donor-recipient HLA-DR mismatch signals high immunologic risk and can result in poor transplant outcomes. Older kidney transplant recipients (KTRs) are more…
2019 American Transplant Congress
Epidemiology of Parvovirus B19 and Anemia among Kidney Transplant Recipients
N. Khoury¹, C. Thongprayoon², N. Leeaphorn³, J. Bruminhent⁴, W. Cheungpasitporn⁵
¹Henry Ford Transplant Institute, Detroit, MI, ²Mayo Clinic, Rochester, MN, ³University of Missouri, Kansas City, MO, ⁴Mahidol University, Bangkok, Thailand, ⁵University of Mississippi, Jackson, MS
*Purpose: Persistent anemia has been described in kidney transplant (KTx) recipients with Parvovirus B19 virus infection. However, epidemiology of Parvovirus B19 and Parvovirus B19-related anemia…
2019 American Transplant Congress
Quality of Life in Tolerant Living Donor Kidney Transplants vs. Standard of Care
D. Tollerud¹, J. Leventhal², J. Galvin², J. Mathew², L. Gallon², D. Stare², J. Miller², M. Abecassis², S. Ildstad³
¹Regenerex, Inc., Louisville, KY, ²Northwestern U, Chicago, IL, ³U of Louisville, Louisville, KY
*Purpose: 37 subjects have been transplanted since 2009 in a phase 2 protocol to induce tolerance in recipients of living donor renal allografts. The protocol…
2019 American Transplant Congress
Outcomes after Incompatible Living Donor Kidney Transplantation in Older Recipients
J. Long¹, K. Jackson¹, J. Motter¹, S. Bae¹, A. Massie¹, M. Waldram¹, K. Covarrubias¹, J. Chen¹, B. Orandi², N. Desai¹, D. Segev¹, J. Garonzik-Wang¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²Surgery, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Older individuals are the fastest-growing sub-group of transplant candidates who may face increased risks when considering incompatible living donor kidney transplantation (IKT) due to…