Articles tagged "Kidney transplantation"

2019 American Transplant Congress
TMA Development in Kidney and Heart Xenografts Treated with Anti-CD40 or Anti-CD154 Antibodies
D. H. Ma¹, H. Sasaki¹, J. M. O¹, K. Ahrens¹, D. Becerra¹, C. G. Rickert¹, D. M. Detelich¹, T. Oura¹, W. Somer¹, I. Rosales², R. N. Pierson¹, J. Markmann¹, J. C. Madsen¹, T. Kawai¹
¹Surgery, MGH, Boston, MA, ²Pathology, MGH, Boston, MA
*Purpose: Genetically modified Galactose-α 1,3-galactose knockout transgenic swine expressing human CD55 (GTKO.hCD55) are resistant to hyperacute rejection of xenografts. We compare anti-CD154 and anti-CD40 antibody-based…
2019 American Transplant Congress
National Landscape of Hope Act Transplant Candidates and Recipients in the United States
A. R. Wilk¹, R. Hunter², M. A. McBride², D. K. Klassen²
¹Research, United Network for Organ Sharing, Richmond, VA, ²United Network for Organ Sharing, Richmond, VA
*Purpose: The HIV Organ Policy Equity (HOPE) Act, enacted on 11/21/13, allows for the transplantation of organs from HIV+ donors into HIV+ recipients in the…
2019 American Transplant Congress
Robotic-Assisted versus Open Techniques for Living Donor Kidney Transplant Recipients: A Comparison Using Propensity Score Analysis
F. Tinney, J. Stracke, S. Nagai, L. Malinzak, T. McEvoy, S. Mohamed Ilias, A. Yoshida
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Following rapid advancements in minimally invasive urology, living donor robotic-assisted kidney transplantation (RAKT) has developed into a feasible alternative to open kidney transplantation (OKT).…
2019 American Transplant Congress
Efficacy and Safety Outcomes with De Novo Use of Everolimus-Based Regimen in Renal Transplant Recipients with Delayed Graft Function from the TRANSFORM Study
S. Chadban¹, F. Oppenheimer¹, F. Citterio¹, O. Witzke¹, V. D. Garcia¹, A. Gutierrez-Dalmau¹, P. Narvekar², M. P. Hernandez Gutierrez², P. Bernhardt², A. Wiseman¹
¹TRANSFORM Study Group, Basel, Switzerland, ²Novartis Pharma AG, Basel, Switzerland
*Purpose: To evaluate the effect of everolimus with reduced CNI (EVR+rCNI) vs mycophenolic acid with standard CNI (MPA+sCNI) on efficacy and safety outcomes in RTxR…
2019 American Transplant Congress
Recipient Outcomes Following Transplantation Of Allografts From Older Live Kidney Donors With Hypertension
F. Al Ammary¹, S. Yu², A. D. Muzaale³, D. C. Brennan⁴, A. C. Wiseman⁵, D. L. Segev³, A. B. Massie³
¹Johns Hopkins Medicine, Greenbelt, MD, ²Johns Hopkins Medicine, Baltimore, MD, ³Surgery, Johns Hopkins Medicine, Baltimore, MD, ⁴Medicine, Johns Hopkins Medicine, Baltimore, MD, ⁵Medicine, University of Colorado, Aurora, CO
*Purpose: Healthy older live kidney donor candidates with hypertension may provide an opportunity to increase live kidney donation. However, the impact of this practice on…
2019 American Transplant Congress
Fifteen Year Outcomes in the Astellas Double Blind Randomized Controlled Trial (RCT) Comparing Early Corticosteroid Withdrawal (CSWD) and Long-Term Corticosteroid Therapy Continuation (CCS) in Kidney Transplantation
E. Woodle¹, S. Clark², D. Stewart³, M. First⁴, R. Alloway⁵, J. Gill⁶, .. Split Rock Group⁷
¹Transplant Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, ²Providence Health Care, Vancouver, BC, Canada, ³UNOS, Richmond, VA, ⁴Transplant Genomics Inc. and Comprehensive Transplant Center, Northwestern University, Evanston, IL, ⁵University of Cincinnati College of Medicine, Cincinnati, OH, ⁶University of British Columbia, Vancouver, BC, Canada, ⁷Yale University, New Haven, CT
*Purpose: To evaluate long-term outcomes among participants in the original multi-center RCT initiated in 1999 (Woodle et al, Annals of Surgery, 2008), and to demonstrate…
2019 American Transplant Congress
“Getting Life Back” – Kidney Transplantation in the Elderly Patient
V. Tsarpali¹, K. Lønning², K. Midtvedt², T. Bernklev³, N. von der Lippe⁴, M. H. Andersen², K. Heldal¹
¹Clinic of Internal Medicine, Telemark Hospital Trust, Skien, Norway, ²Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway, ³Vestfold Hospital Trust, Tønsberg, Norway, ⁴Oslo University Hospital, Oslo, Norway
*Purpose: The number of elderly patients developing end stage renal disease (ESRD) who are eligible for kidney transplantation (KTx) is increasing, but their transplant rate…
2019 American Transplant Congress
Surgeon Readiness For Entry Into Practice: A Survey Of Abdominal Transplant Surgeons In The United States
M. Abouljoud¹, R. Hirose², S. Nagai¹, C. Gordon³, D. Farmer⁴
¹Henry Ford Transplant Institute, Detroit, MI, ²Transplant Surgery, University of California San Francisco, San Francisco, CA, ³American Society of Transplant Surgeons, Arlington, VA, ⁴Transplant Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA
*Purpose: The American Society of Transplant Surgeons (ASTS) provides a framework for the training and development of a competent transplant surgery workforce. Practice-readiness and phase-in…
2019 American Transplant Congress
Cardiovascular Mortality in Transplant Patients; A Population-Based Cohort Study 1988-2013 in Australia and New Zealand
M. Wyld¹, N. De La Mata², P. Masson³, E. O'Lone², A. Webster²
¹Renal Department, Royal Prince Alfred Hospital, Camperdown, Australia, ²School of Public Health, University of Sydney, Sydney, Australia, ³Renal Department, Royal Free London NHS Foundation Trust, London, United Kingdom
*Purpose: Transplant recipients experience excess cardiovascular morbidity and mortality. We compared cardiovascular death rates in kidney transplant recipients to the general population and identified risk…
2019 American Transplant Congress
Gut Dysbiosis Predominates Post-Transplant Diarrhea in Kidney Transplant Recipients: A Validation Study
L. Zhang, J. Lee, M. Magruder, E. Edusei, D. Dadhania, M. Lubetzky, S. Albakry, B. Botticelli, E. Pamer, M. Suthanthiran
Weill Cornell Medicine, New York, NY
*Purpose: Lower abundance of commensal bacterial taxa in the gut has been previously described in a recent study of kidney transplant recipients with post-transplant diarrhea…