Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Long-Term Outcomes Following Uncontrolled Donation after Cardiac Death Kidney Transplantation: Opportunity for Increasing Donor Pool?
R. A. Choudhury, K. Prins, D. Yoeli, H. B. Moore, T. L. Nydam
Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Uncontrolled donation after cardiac death (uDCD) represents an underutilized source of donors in the United States. However, controversy surrounding the long-term durability of uDCD…
2019 American Transplant Congress
Shroom3 Regulates Glomerular Hypertrophy after Uninephrectomy via mTOR
K. Banu, F. Garzon, C. Wei, Z. Yi, W. Zhang, C. He, B. Murphy, M. C. Menon
Mount Sinai School of Medicine, New York, NY
*Purpose: A Shroom3 intronic risk locus & Shroom3 protein have been associated with increased fibrosis but reduced albuminuria in recipients of allografts with the risk…
2019 American Transplant Congress
CD19+ Cell Behavior in the 12 Months Following a Single Dose of Rituximab in Patients with Humoral Rejection: Clinical and Histological Outcomes
L. Marino, I. A. Martínez-Juárez, J. R. Marino-Sánchez, J. I. Santander-Velez, F. Zamora, H. Juarez, R. Vazquez, L. Llorente, G. Lima, A. Cohen-Bucay, L. E. Morales-Buenrostro
Nephrology, INCMNSZ, Mexico City, Mexico
*Purpose: Treatment of antibody mediated rejection (ABMR) commonly includes rituximab, but the dose needed is not yet well defined. It has been suggested that a…
2019 American Transplant Congress
Mismatched Epitope and De Novo DSA Development: An Analysis of the Benefit and Benefit-EXT Renal Transplant Cohorts
V. Jucaud¹, V. Burnett¹, H. Gebel², R. Bray², M. Polinsky³, M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Emory University, Atlanta, GA, ³Bristol-Myers Squibb, Princeton, NJ
*Purpose: De novo donor-specific HLA antibodies (dnDSA) target epitopes rather than whole antigens, and their development is associated with the mismatched HLA antibody epitope load…
2019 American Transplant Congress
The Degree of Glomerulosclerosis in Procurement Renal Biopsy and its Implications in Predicting Graft Outcomes in Marginal Donor Kidneys
W. Cheungpasitporn¹, W. Chon², E. Island², L. Cummings², J. Forster², N. Leeaphorn²
¹University of Mississippi Medical Center, Jackson, MS, ²Saint Luke's Health System, Kansas City, MO
*Purpose: Percentage of glomerulosclerosis (GS) is a major determinant for kidney discard. However, GS failed to consistently predict graft outcomes across studies in the literature.…
2019 American Transplant Congress
An Immediate and Persistent Post-Reperfusion Metabolic Collapse Precedes Delayed Graft Function (DGF)
J. Lindeman
Surgery, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Delayed graft function (DGF) is the manifestation of ischemia reperfusion injury (IRI) in the context of kidney transplantation. Despite clear preclinical successes, a proven…
2019 American Transplant Congress
Clazakizumab as an Agent to Reduce Donor Specific HLA Antibodies and Improve Outcomes in Patients with Chronic & Active Antibody-Mediated Rejection Post-Kidney Transplantation
S. C. Jordan¹, N. Ammerman¹, M. Toyoda², E. Huang¹, C. C. Nast³, A. Peng¹, S. Sethi¹, R. Najjar¹, I. Kim¹, K. Lim¹, J. Choi¹, A. Vo¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Ctr, Los Angeles, CA, ²Transplant Immunology Lab, Cedars-Sinai Medical Ctr, Los Angeles, CA, ³Department of Pathology, Cedars-Sinai Medical Ctr, Los Angeles, CA
*Purpose: Highly sensitized (HS) patients are at an increased risk for chronic antibody mediated rejection (cABMR) and graft loss due to persistent, deleterious DSA production.…
2019 American Transplant Congress
Association between Medicaid Expansion under the Affordable Care Act and Preemptive Kidney Transplantation of Low-Income Medicaid Beneficiaries
M. N. Harhay¹, R. McKenna²
¹Medicine, Drexel University College of Medicine, Philadelphia, PA, ²Health Management and Policy, Drexel University Dornsife School of Public Health, Philadelphia, PA
*Purpose: The lack of affordable health insurance options is a known barrier to preemptive kidney transplantation (KT) among low-income individuals with non-dialysis dependent chronic kidney…
2019 American Transplant Congress
Outcomes Of Single And En-bloc Pediatric Kidneys According To Kdpi
M. Sampaio, E. Lum, A. Gritsch, S. Bunnapradist
David Geffen Sch of Med at UCLA, Los Angeles, CA
*Purpose: There is no consensus on whether a very young kidney should be used as en-bloc or single. We studied the association of KDPI in…
2019 American Transplant Congress
Nationwide Survey of Human T Cell Leukemia Virus Type 1-Infected Kidney Transplant Recipients in Japan
J. Yamauchi¹, Y. Yamano¹, M. Matsuoka², N. Ichimaru³, M. Nishikido⁴, Y. Shibagaki⁵, A. Sugitani⁶, N. Nakamura⁷, M. Mieno⁸, K. Yuzawa⁹
¹Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²Institute for Virus Research, Kyoto University, Kyoto, Japan, ³Advanced Technology for Transplantation, Osaka University, Osaka, Japan, ⁴Blood Purification Center, Nagasaki University, Nagasaki, Japan, ⁵Department of Nephrology and Hypertention, St. Marianna University School of Medicine, Kawasaki, Japan, ⁶NHO Yonago Medical Center, Yonago, Japan, ⁷Fukuoka University, Fukuoka, Japan, ⁸Center for Information, Jichi Medical University, Shimotsuke, Japan, ⁹Department of Transplantation Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan
*Purpose: Human T-cell leukemia virus type 1 (HTLV-1) infects 5 to 10 million people worldwide, and is endemic in Japan, sub-Saharan Africa, South America, and…