Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Evaluation of the Economic Impact of a New IVD Immunoassay (Immunobiogram) for Immunosuppressive Treatment Adjustment in Kidney Transplant Recipients in Spain
C. Rubio¹, C. Jiménez², M. Crespo³, J. Portolés⁴, D. Rubio¹, T. Diez⁵, I. Portero⁵
¹Health Value, Madrid, Spain, ²La Paz Hospital, Madrid, Spain, ³Consorci Mar Parc de Salut, Barcelona, Spain, ⁴Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, ⁵Biohope Scientific Solutions for Human Health SL, Madrid, Spain
*Purpose: Immunobiogram (IMBG) is a new IVD bioassay developed by Biohope SL with the aim to support clinicians in the personalized adjustment of immunosuppressive therapy…
2020 American Transplant Congress
Evolution of Molecular MMDx Scores after Kidney Transplantationin Different Donor Categories
P. Hruba¹, K. S. Madill-Thomsen², M. Mackova², J. Maluskova³, E. Honsova³, J. Slatinska⁴, P. F. Halloran², O. Viklicky⁴
¹Transplant Laboratory, IKEM, Prague, Czech Republic, ²ATAGC, University of Alberta, Edmonton, AB, Canada, ³Department of Pathology, IKEM, Prague, Czech Republic, ⁴Department of Nephrology, IKEM, Prague, Czech Republic
*Purpose: The outcome of kidney transplantation is highly affected by donor category. Little is known about molecular processes which may underline this phenomenon.*Methods: Using Molecular…
2020 American Transplant Congress
Risk Factors for the Development of Avascular Necrosis: Single Center Experience
A. Karakok¹, A. Velioglu², I. H. Arikan², E. Asicioğlu², S. Tuglular¹
¹Marmara University School of Medicine, Istanbul, Turkey, ²Nephrology, Marmara University School of Medicine, Istanbul, Turkey
*Purpose: Avascular necrosis (AVN) is one of the most common bone complications after kidney transplantation. In recent years, it has become an important morbidity with…
2020 American Transplant Congress
The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction
G. Castellano¹, B. Infante¹, P. Pontrelli¹, R. Franzin¹, F. Rascio¹, C. Prisciandaro², L. Gesualdo¹, N. Coviello³, G. Grandaliano³, G. Stallone³
¹Emergency and Organ Transplantation, University of Bari, Bari, Italy, ²University of Foggia, Foggia, Italy, ³Emergency and Organ Transplantation, University of Foggia, Foggia, Italy
*Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
2020 American Transplant Congress
Outcomes of Acute Allograft Rejection Treatment with R Anti-Thymocyte Globulin (r-ATG) One Year Post Kidney Transplant
M. Yaqub, A. Riaz, D. Mishler, O. Adebiyi, T. Taber, A. Sharfuddin
Indiana University School of Medicine, Indianapolis, IN
*Purpose: Acute allograft rejection is considered one of the major causes of renal allograft dysfunction. Despite maximal anti-rejection therapy grafts may not regain baseline function.…
2020 American Transplant Congress
Operative vs. Non-Operative Management of Hemorrhage in the Postoperative Kidney Transplant Patient
R. Shaw¹, T. Reavis¹, V. Meruva², F. Montz³, E. Rogers⁴, A. Kumar¹, V. Bowers⁴, J. Buggs⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Lake Erie College of Osteopathic Medicine, Bradenton, FL, ³University of Tampa, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Postoperative hemorrhage has been described at rates of 14 percent in kidney transplant (KT) literature. The preferred management of postoperative hemorrhage in this population…
2020 American Transplant Congress
Incidence of Urinary Tract Infections in Kidney Transplant Recipients Receiving Alternate Antimicrobial Prophylaxis Regimens
D. Quan¹, J. Phillips¹, E. Chiang¹, V. Kuo²
¹UCSF Health, San Francisco, CA, ²UC Davis, Davis, CA
*Purpose: Urinary tract infections (UTI) occur frequently in renal transplant (RT) recipients. Antimicrobial prophylaxis may help prevent UTI early post RT. Trimethoprim/sulfamethoxazole (TMP/SMX) is the…
2020 American Transplant Congress
The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function
S. Costa¹, F. Barroso¹, C. Oliveira¹, E. Daher¹, P. Fernandes¹, L. Andrade², R. Esmeraldo³, T. Sandes-Freitas¹
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, ³Hospital Geral de Fortaleza, Fortaleza, Brazil
*Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
2020 American Transplant Congress
Two Pilot Studies Exploring the Diagnostic and Predictive Potential of Serum LAG3 and FGL1 in Kidney Transplant Recipients
Y. Li¹, L. Yan¹, Y. Li¹, C. Yang¹, Z. Wan¹, Y. An¹, Y. Bai¹, L. Wang¹, Y. Shi²
¹Department of Laboratory Medicine, West China Hospital, Chengdu, China, ²Department of Nephrology, West China Hospital, Chengdu, China
*Purpose: Lymphocyte activation gene 3 (LAG3), an immune checkpoint, plays an important role in the negative regulation of immune response and the induction of immune…
2020 American Transplant Congress
Tyrosine Receptor Kinase Axl Regulates Intragraft Trafficking of Alloreactive T Cells Post Kidney Transplantation
A. Dangi¹, K. Glinton², M. Sharma¹, S. Yu¹, M. DeBerge², E. B. Thorp², X. Luo¹
¹Nephrology/Medicine, Duke University, Durham, NC, ²Pathology, Northwestern University, Chicago, IL
*Purpose: Previous studies have shown that receptor tyrosine kinase Axl, primarily expressed on dendritic cells and some tissue-specific macrophage population, is required for T cells…