Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis
J. McDaniels¹, A. Shetty¹, C. Kuscu², C. Kuscu², T. Rousselle¹, E. Bardhi¹, C. Drachenberg¹, M. Talwar², J. Eason², T. Muthukumar³, D. Maluf¹, V. Mas¹
¹University of Maryland Baltimore, Baltimore, MD, ²UTHSC, Memphis, TN, ³Weill Cornell Medicine, New York, NY
*Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
2022 American Transplant Congress
Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients
A. Santos¹, H. Ibrahim¹, M. A. Leghrouz¹, X. Wen²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kinston, RI
*Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
2022 American Transplant Congress
Outcomes Following Renal Transplant with Hepatitis C Viremic Donors in an Elderly Veteran Population with Preemptive Mayvret Therapy
R. Lopez-Soler¹, A. Thorndyke¹, C. Trotter¹, A. Abadier², M. Samra¹
¹Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, ²Surgery, Loyola University School of Medicine, Maywood, IL
*Purpose: Overall mortality on the kidney transplant waiting list is higher for older diabetic patients. The average age of waitlisted veteran patients is 64, with…
2022 American Transplant Congress
Successful Kidney Transplantation from a Deceased Donor with Severe COVID-19: Undetectable SARS-CoV-2 in Donor Kidney and Aorta by Sensitive Molecular Testing
K. Lee¹, N. M. Desai¹, J. Resnick², M. Li², A. Johanson¹, A. Pekosz², H. Rabb¹, J. L. Mankowski¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
*Purpose: Kidney transplantation (KT) from coronavirus disease 2019 (COVID-19) positive donors has been avoided due to concerns for donor-derived transmission and possibility of the kidney…
2022 American Transplant Congress
The Impact of the New Allocation System of Kidney Transplantation on a Single Institution
M. Eltemamy, Y. Lin, M. Khalil, S. Agrawal, V. Krishnamurthi, A. Wee
The Cleveland Clinic, Cleveland, OH
*Purpose: The new kidney allocation system went into effect in the middle of March 2021. The consequences of this new system affected transplant centers differently,…
2022 American Transplant Congress
Single Center Retrospective Study Examining the Safety of the New Potassium- Binders for Post-Operative Hyperkalemia in Kidney Transplant Recipients
S. Kapoor¹, A. Campbell², Y. Azzi¹, L. E. Liriano-Ward³, T. Shertel⁴, W. Xiao⁵, D. U. Nnani⁶, S. Farghaly¹, S. Yun⁷, E. Akalin¹, M. Ajaimy¹
¹Einstein-Montefiore Transplant Center, Bronx, NY, ²Montefiore Medical Center, Bronx, NY, ³Transplant, Montefiore Medical Center, Bronx, NY, ⁴-, -, AL, ⁵Albert Einstein College of Medicine, Folsom, CA, ⁶Pharmacy, Montefiore Medical Center, Bronx, NY, ⁷Montefiore Medical Center, New York, NY
*Purpose: We aimed to evaluate the safety and efficacy of two potassium-binders (Patiromer and Sodium Zirconium Cyclosilicate (SZC) in early post-transplant hyperkalemia treatment of kidney…
2022 American Transplant Congress
Effect of Schisandra Sphenanthera Extract on Pharmacokinetics of Tacrolimus in Pediatric Renal Transplant Recipients
J. Jiang¹, H. Zhang¹, X. Su¹, S. Wu¹, Y. Chen², W. Chen², J. Li², C. Wu², L. Yang², L. Liu², C. Wang²
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Wuzhi tablet (Schisandra sphenanthera extract) is a promising tacrolimus-sparing agent in adult renal transplant recipients, while its effect in pediatric recipients remains unclear. The…
2022 American Transplant Congress
Adding Epitope Compatibility To Deceased Donor Kidney Allocation Criteria: Recommendations From An Online Public Deliberation
L. Edwards¹, R. Sapir-Pichhadze², P. Keown³, S. Bryan¹
¹School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, ²McGill University, Montreal, QC, Canada, ³Department of Medicine, University of British Columbia, Vancouver, BC, Canada
*Purpose: With increasing demand for kidneys and a scarce supply, ways to reduce rejection and improve transplant outcomes are needed. One possibility is using epitope…
2022 American Transplant Congress
In Vitro Fertilization Use Among Female Kidney Transplant Recipients
L. A. Coscia¹, J. M. Konel², M. Bowring³, S. Constantinescu⁴, M. J. Moritz⁵
¹Transplant Pregnancy Registry International, Philadelphia, PA, ²Wayne State University School of Medicine, Detroit, MI, ³Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁵Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: Infertility is common among female kidney transplant recipients (KTRs). In vitro fertilization (IVF) is a potential option. The purpose of this study was to…
2022 American Transplant Congress
First Report of Xenotransplantation from a Pig to Human Recipient
J. Stern¹, V. Tatapudi¹, B. Lonze¹, Z. Stewart¹, M. Mangiola¹, M. Wu¹, S. Mehta¹, E. Weldon¹, R. Dieter¹, N. Lawson¹, A. Griesemer², B. Parent¹, G. Piper¹, P. Sommer¹, S. Cawthon¹, B. Sullivan¹, N. Ali¹, R. A. Montgomery¹
¹NYU Langone Transplant Institute, New York, NY, ²CUMC, New York, NY
*Purpose: Xenotransplantation of genetically edited pig organs into human recipients can solve the global scarcity of organs for transplantation. Humans lack the α1,3-Gal glycan ubiquitously…