Articles tagged "Kidney transplantation"

2020 American Transplant Congress
The Effect of Pulsatile Pump Perfusion on Hepatitis C Viremia and Transmission in Kidney Transplantation: A Prospective Pilot Study
R. Forbes¹, B. Concepcion¹, D. Clapper², B. Dubray¹, A. Miller², D. Shaffer¹, K. Johnson²
¹Vanderbilt University Medical Center, Nashville, TN, ²Tennessee Donor Services, Nashville, TN
*Purpose: With increasing utilization of hepatitis C (HCV) viremic donor organs for aviremic recipients, there may be a role for kidney pulsatile pump perfusion to…
2020 American Transplant Congress
Use of Sitagliptin versus Placebo to Reduce the Incidence and Severity of Post-Transplant Diabetes after Kidney Transplantation
H. Wijeweera, J. Hagopian, M. Ramakrishnan, L. Chen, R. Delos Santos
Washington University in St. Louis, Saint Louis, MO
*Purpose: Post-transplant diabetes mellitus (PTDM) is a complication in non-diabetic kidney transplant (KT) recipients due weight gain and use of CNI and corticosteroids in immunosuppression…
2020 American Transplant Congress
Hepatitis C Antibody Seroconversion in Kidney Transplant Patients from HCV Antibody Positive/NAT Negative Donors Does Not Deteriorate Renal Allograft Outcome
R. Rattanavich, M. De Vera, T. Hoang, R. Villicana
Loma Linda University, Transplant Institute, San Bernadino, CA
*Purpose: Prior studies have shown that almost 50% of kidney transplant patients from hepatitis C Ab+/NAT - donors have seroconverted but its impact on renal…
2020 American Transplant Congress
Trust and Transparency in Artificial Intelligence-Aided Immunosuppression Decisions
J. Clement
Information and Decision Sciences, University of Minnesota, Minneapolis, MN
*Purpose: In transplant, there is significant interest in using Artificial Intelligence (including machine learning or predictive models) Clinical Decision Support Systems(AI CDSS). Properly designing and…
2020 American Transplant Congress
Predictors of Estimated GFR and Recurrent Chronic Kidney Disease (CKD) after Simultaneous Liver and Kidney Transplantation (SLKT): Results from the US Multicenter SKLT Consortium
P. Sharma¹, Z. Sui¹, M. Zhang¹, J. Magee¹, P. Barman², Y. Patel³, K. Walters⁴, S. Biggins⁵, A. Schluger⁶, G. Cullaro⁷, R. Wong⁸, J. Lai⁸, J. Jo⁹, J. Sinha⁹, L. VanWagner⁹, E. Verna⁷
¹Michigan Medicine, Ann Arbor, MI, ²UCSD, San Diego, CA, ³Duke, Durham, NC, ⁴UCLA, LA, CA, ⁵University of Washington, Seattle, WA, ⁶Westchester Medical Center, Weschester, NY, ⁷Columbia, New York, NY, ⁸UCSF, San Francisco, CA, ⁹Northwestern, Chicago, IL
*Purpose: SLKT is a life-saving intervention for patients with decompensated cirrhosis and concomitant end stage renal disease, irreversible acute kidney injury and select inherited metabolic…
2020 American Transplant Congress
Crispr-Based Diagnostics for Rejection and Opportunistic Infection Detection in Kidney Transplantation
I. T. Lape¹, M. M. Kaminski², E. Akalin³, J. Collins², L. W. Riella¹
¹Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, ²Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, ³Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY
*Purpose: There is an unmet need in transplantation to identify allograft injury non-invasively. More than 50% of patients with kidney transplants lose their grafts within…
2020 American Transplant Congress
Acute Kidney Injury in Deceased Organ Donors and Kidney Transplant Outcomes Using a Novel Data Source
E. M. Sonnenberg, J. Hsu, J. Cohen, V. Potluri, M. H. Levine, P. L. Abt, P. P. Reese
Perelman School of Medicine, University of Pennsyl, Philadelphia, PA
*Purpose: The kidney shortage necessitates innovative approaches to expand the donor pool. Acute kidney injury(AKI) is common among deceased donors and a risk factor for…
2020 American Transplant Congress
Early Outcomes with the Liver-Kidney Safety Net
R. M. Cannon¹, D. S. Goldberg², D. E. Eckhoff¹, D. J. Anderson¹, B. J. Orandi¹, J. E. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Miami, Miami, FL
*Purpose: A safety net policy was implemented in August 2017 giving liver alone recipients with significant renal dysfunction post-transplant priority for subsequent renal transplantation. This…
2020 American Transplant Congress
Change In i-IFTA Associated with Treatment of Rejection
N. Garg, B. C. Astor, S. Parajuli, F. Aziz, M. Mohamed, W. Zhong, A. Djamali, D. A. Mandelbrot
UW-Madison, Madison, WI
*Purpose: Recent studies have shown that inflammation in areas of interstitial fibrosis and tubular atrophy (i-IFTA) is associated with worse kidney allograft outcomes. How i-IFTA…
2020 American Transplant Congress
Apoptotic Exosome-Like Vesicles are Associated with Alloimmune Vascular Injury in Kidney Transplant Recipients
M. Dieude¹, E. Boilard², I. Allaeys², A. Deneault-Marchand¹, J. Turgeon¹, E. Dore², S. Lariviere-Beaudoin¹, A. Karakeussian-Rimbaud¹, S. Collette³, L. Senecal³, M. Hebert¹, H. Cardinal¹
¹Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, ²Centre de Recherche du Centre Hospitalier de l'Université de Québec, Quebec, QC, Canada, ³Hopital Maisonneuve-Rosemont, Montreal, QC, Canada
*Purpose: There is no non-invasive biomarker of alloimmune vascular injury. We have previously characterized exosome-like vesicles enriched in active proteasome and LG3 (ApoExo) that are…