Articles tagged "Kidney transplantation"

2020 American Transplant Congress
The Economic Impact of HCV D+/R- Kidney Transplantation
S. Meade¹, M. A. Simpson², E. D. Walshe¹, M. E. Akoad², F. D. Gordon²
¹Lahey Clinic, Burlington, MA, ²Transplantation, Lahey Clinic, Burlington, MA
*Purpose: In September 2018, we began offering carefully screened kidney transplant candidates the opportunity for transplantation with kidneys from hepatitis C (HCV) positive deceased donors.…
2020 American Transplant Congress
A New Diagnostic Approach to HLA Testing in Kidney Transplant Patients Using Renal Epithelial Cells
M. Herrmann¹, C. Bach², K. X. Knaup¹, M. Schiffer¹, B. Spriewald², M. S. Wiesener¹
¹Nephrology and Hypertension, University Hospital Erlangen, Erlangen, Germany, ²Haematology and Oncology, University Hospital Erlangen, Erlangen, Germany
*Purpose: In this study we present a new diagnostic approach to HLA typing in kidney transplant recipients using cultured renal tubular cells from urine samples…
2020 American Transplant Congress
Prevalence and Predictors of Sensory Polyneuropathic Signs and Symptoms in Renal Transplant Recipients
S. Nolte¹, J. Hofman¹, A. Gomes-Neto¹, B. de Greef², J. Elting¹, M. Eisenga¹, M. van Londen¹, S. Bakker¹, I. Nolte¹, C. Faber², J. Sanders¹, D. Touw¹, I. Lesman-Leegte¹, S. Berger¹, G. Drost¹
¹University Medical Center Groningen, Groningen, Netherlands, ²Maastricht University Medical Center, Maastricht, Netherlands
*Purpose: Sensory polyneuropathy is a common finding in renal transplant recipients (RTR). Patients with end stage renal disease are at a high risk to develop…
2020 American Transplant Congress
Single Cell Analysis Reveals Endothelial Activation of Interleukin-6 Mediated Signaling Pathway in Microvascular Inflammation with and without c4d
A. S. Naik¹, R. Menon¹, E. Farkash¹, E. Otto¹, C. C. Berthier¹, S. Norman¹, M. Samaniego², M. Kretzler¹
¹University of Michigan, Ann Arbor, MI, ²Henry Ford Hospital, Detroit, MI
*Purpose: Microvascular inflammation (MVI) is a feature of antibody mediated rejection. MVI can be seen with or without activation of other effectors of antibody injury…
2020 American Transplant Congress
A Video Education Intervention to Improve Kidney Transplant Knowledge and Self-Efficacy in Dialysis Center End Stage Renal Disease (ESRD) Patients
D. A. DuBay¹, T. Morinelli¹, Z. Sutton¹, M. Chastain¹, T. Thompkins Tindal¹, Z. Su¹, E. Weeda¹, P. Mauldin¹, M. Casey¹, J. Bian¹, J. Rodrigue², P. Baliga¹, D. Taber³
¹Medical University of South Carolina`, Charleston, SC, ²Departments of Surgery and Psychiatry, Beth Israel Deaconiess Medical Center, Boston, MA, ³Department of Surgery, Medical University of South Carolina`, Charleston, SC
*Purpose: Only 34% of incident ESRD patients are referred for transplant (Tx) evaluation within 12 months of initiating dialysis. There is great need for effective…
2020 American Transplant Congress
Is Dual Allocation Successful at Higher Remuzzi Scores? Outcomes of Dual Kidney Transplants at Remuzzi Scores of 8 or Greater
V. Fleetwood¹, C. Kensinger², C. Papageorge¹, D. Aufhauser¹, G. Leverson³, B. Welch¹, D. Foley¹, P. Pasha¹
¹Department of Transplantation, University of Wisconsin, Madison, WI, ²Department of Transplantation, Piedmont Transplant Center, Atlanta, GA, ³Department of Statistics, University of Wisconsin, Madison, WI
*Purpose: The Remuzzi score (RS) is a histologic assessment of donor kidneys based on degree of glomerulosclerosis, arterial narrowing, interstitial fibrosis, and tubular atrophy. The…
2020 American Transplant Congress
Are Molecular Diagnoses of Antibody Mediated Rejection (ABMR) Reliable in the Setting of Antibody-Antigen Complex Mediated Tissue Injury Unrelated to Alloimmunity?
P. Randhawa¹, Y. Huang¹, G. Tseng², K. Xiao³
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ³Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, Pittsburgh, PA
*Purpose: Transcriptomics based tests for ABMR are now available commercially. The reliability of these tests in clinical settings where allograft tissue is damaged by antibody-antigen…
2020 American Transplant Congress
Multi- National Survey among Nephrologists & Transplant Surgeons about the Suitability and Acceptance of the Marginal Living Kidney Donors with Microscopic Hematuria
Z. Arabi¹, S. Kaysi², A. Hamad³, M. Bukhari⁴
¹KAMC, Riyadh, Saudi Arabia, ²CHU Clermont-Ferrand, Orleans, French Guiana, ³The Regional Medical Center, Orangeburg, SC, ⁴Taif University, Taif, Saudi Arabia
*Purpose: Potential kidney donors with isolated hematuria are often excluded from donating although there is a wide controversy about the definition and threshold of investigations…
2020 American Transplant Congress
Late Conversion from Calcineurin Inhibitors to Belatacept in Kidney-Transplant Recipients Has a Significant Beneficial Impact on Glycemic Parameters
J. Noble, F. Terrec, T. Jouve, H. Neciri Bennani, P. Benhamou, P. Malvezzi, B. Janbon, D. Giovannini, L. Rostaing
Nephrology and Transplant Unit, CHU Grenoble, Grenoble, France
*Purpose: Calcineurin inhibitors (CNIs) and steroids are strongly associated with new-onset diabetes after transplantation (NODAT), worsening of pre-existing diabetes, and cardiovascular events. We assessed the…
2020 American Transplant Congress
Mycophenolate Mofetil and the Incidence of Skin Cancer in Kidney Transplant Recipients
S. J. Yusuf¹, H. Bheemreddy¹, A. Imtiaz², N. Krishnan³
¹Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom, ²Dermatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, ³Renal Unit, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom
*Purpose: Over the years there has been a shift in the use of anti-metabolites agents from azathioprine to mycophenolate mofetil (MMF) based immunosuppression., due to…