Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Donor-Derived Cell-Free DNA Combined with Histology Improves Prediction of eGFR Decline in Kidney Transplant Recipients over Histology Alone
M. Gillespie, M. Haas, K. Lim, A. Vo, A. Peng, R. Najjar, S. Sethi, S. Jordan, E. Huang
Cedars-Sinai, Los Angeles, CA
*Purpose: Higher Banff inflammation and chronicity scores on kidney transplant (KTx) biopsies (Bx) have been associated with poorer graft survival, but Bx scores alone imperfectly…
2020 American Transplant Congress
Changes in Gut Microbiota and Acute Rejection after Kidney Transplantation
H. Cho¹, J. Kim², H. Kim², J. Park³, M. Kwak⁴, B. Kim⁴, D. Kim², J. Lee⁵, B. Kim⁶, H. Lee²
¹Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea, Republic of, ²Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea, Republic of, ⁴ChunLab Inc. Seoul National University, Seoul, Korea, Republic of, ⁵Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Department of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Korea, Republic of
*Purpose: Kidney transplantation (KT) is the best treatment for end-stage renal disease. Although rejection is a normal immune response of the body to a foreign…
2020 American Transplant Congress
Valganciclovir for Epstein-Barr Virus Prevention after Pediatric Kidney Transplant
R. Jackson¹, S. Mehra², E. Smith¹, C. Peterson², E. Benefield¹, R. Ensign¹, J. Sherbotie², C. Heyrend¹
¹Intermountain Healthcare, Salt Lake City, UT, ²University of Utah, Salt Lake City, UT
*Purpose: Epstein-Barr virus (EBV) infection after pediatric kidney transplant (pKTx) is common and can lead to post transplant lymphoproliferative disorder (PTLD). Valganciclovir (VGN) is used…
2020 American Transplant Congress
Is Dual Allocation Successful at Higher Remuzzi Scores? Outcomes of Dual Kidney Transplants at Remuzzi Scores of 8 or Greater
V. Fleetwood¹, C. Kensinger², C. Papageorge¹, D. Aufhauser¹, G. Leverson³, B. Welch¹, D. Foley¹, P. Pasha¹
¹Department of Transplantation, University of Wisconsin, Madison, WI, ²Department of Transplantation, Piedmont Transplant Center, Atlanta, GA, ³Department of Statistics, University of Wisconsin, Madison, WI
*Purpose: The Remuzzi score (RS) is a histologic assessment of donor kidneys based on degree of glomerulosclerosis, arterial narrowing, interstitial fibrosis, and tubular atrophy. The…
2020 American Transplant Congress
Are Molecular Diagnoses of Antibody Mediated Rejection (ABMR) Reliable in the Setting of Antibody-Antigen Complex Mediated Tissue Injury Unrelated to Alloimmunity?
P. Randhawa¹, Y. Huang¹, G. Tseng², K. Xiao³
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ³Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, Pittsburgh, PA
*Purpose: Transcriptomics based tests for ABMR are now available commercially. The reliability of these tests in clinical settings where allograft tissue is damaged by antibody-antigen…
2020 American Transplant Congress
Multi- National Survey among Nephrologists & Transplant Surgeons about the Suitability and Acceptance of the Marginal Living Kidney Donors with Microscopic Hematuria
Z. Arabi¹, S. Kaysi², A. Hamad³, M. Bukhari⁴
¹KAMC, Riyadh, Saudi Arabia, ²CHU Clermont-Ferrand, Orleans, French Guiana, ³The Regional Medical Center, Orangeburg, SC, ⁴Taif University, Taif, Saudi Arabia
*Purpose: Potential kidney donors with isolated hematuria are often excluded from donating although there is a wide controversy about the definition and threshold of investigations…
2020 American Transplant Congress
Late Conversion from Calcineurin Inhibitors to Belatacept in Kidney-Transplant Recipients Has a Significant Beneficial Impact on Glycemic Parameters
J. Noble, F. Terrec, T. Jouve, H. Neciri Bennani, P. Benhamou, P. Malvezzi, B. Janbon, D. Giovannini, L. Rostaing
Nephrology and Transplant Unit, CHU Grenoble, Grenoble, France
*Purpose: Calcineurin inhibitors (CNIs) and steroids are strongly associated with new-onset diabetes after transplantation (NODAT), worsening of pre-existing diabetes, and cardiovascular events. We assessed the…
2020 American Transplant Congress
Mycophenolate Mofetil and the Incidence of Skin Cancer in Kidney Transplant Recipients
S. J. Yusuf¹, H. Bheemreddy¹, A. Imtiaz², N. Krishnan³
¹Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom, ²Dermatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, ³Renal Unit, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom
*Purpose: Over the years there has been a shift in the use of anti-metabolites agents from azathioprine to mycophenolate mofetil (MMF) based immunosuppression., due to…
2020 American Transplant Congress
Kidney Transplantation after Multiple Myeloma: The Last 2 Decades
V. Nair, K. Jhaveri, M. Abate
Medicine, Northwell Health, Manhasset, NY
*Purpose: Due to recent advances, patients with a history of multiple myeloma (MM) and ESKD are more frequently offered kidney transplantation (Ktx). Existing literature does…
2020 American Transplant Congress
Impact of Immunosuppression on Quality of Life among HLA-Identical Living Kidney Recipients at UCLA – A Qualitative Study
E. L. Wood¹, S. George², N. Kogut¹, E. Lum, MD³, J. L. Veale¹
¹Urology, UCLA, Los Angeles, CA, ²Fielding School of Public Health, UCLA, Los Angeles, CA, ³Medicine, Nephrology, UCLA, Los Angeles, CA
*Purpose: Tolerant kidney transplant recipients (off immunosuppression) report higher self-rated quality of life and a lower symptom burden compared to standard living recipients when using…