Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients
A. Kosoku¹, J. Uchida¹, T. Ishihara², T. Iwai¹, H. Shimada¹, K. Kabei¹, S. Nishide¹, T. Naganuma¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan
*Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
2020 American Transplant Congress
Impact of PD1, PDL1 Gene Polymorphisms on Allo-Immune Responses after Kidney Transplantation
H. Yamane, Y. Tanaka, M. Ohira, H. Tahara, K. Ide, H. Ohdan
Hiroshima University, Hiroshima, Japan
*Purpose: The programmed death (PD)-1/PD-1 ligands (PD-Ls) pathway, a member of the B7/CD28 family, triggers an immune checkpoint resulting in inhibition of T cells. Several…
2020 American Transplant Congress
Prevalence of Frailty and Cognitive Impairment at Time of Kidney Transplant Evaluation
J. Klein, A. Jurgensen, M. Gupta, N. Herrera, A. Gupta, D. Cibrik
Internal Medicine, Division of Nephrology, University of Kansas Medical Center, Kansas City, KS
*Purpose: Frailty is highly prevalent in kidney disease, with prevalence estimates as high as 73% in patients at the time of dialysis initiation compared to…
2020 American Transplant Congress
Incident Malignancies among Post Kidney-Transplant Patients by Type of Induction Immunosuppression and by Age
L. Wang, J. Motter, S. Bae, D. Segev, M. McAdams DeMarco
Johns Hopkins University, Baltimore, MD
*Purpose: Adult kidney-transplant (KT) recipients have a differential risk of malignancies based on their induction immunosuppression (IS) therapy. However, older recipients are more likely to…
2020 American Transplant Congress
Optimal Timing of Renal Transplantation in Simultaneous Heart-Kidney Transplant: A Retrospective Analysis of the UNOS/OPTN Database
A. S. Karim, G. E. Leverson, J. W. Smith, D. P. Foley
Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: In patients receiving a simultaneous heart-kidney transplant (SHKT) the optimal timing of performing the kidney transplant remains controversial. In the immediate approach (iHKT), the…
2020 American Transplant Congress
Easier Said Than Done? Stated versus Actual Usage of Less-Than-Ideal Kidneys
D. Stewart, H. McGehee, J. Rosendale, D. Klassen
United Network for Organ Sharing, Richmond, VA
*Purpose: Despite long candidate waiting times and a persistent supply to demand gap, less-than-ideal (LTI) kidneys continue to be underutilized in the U.S. Usage rates…
2020 American Transplant Congress
The Economic Impact of National Standardization of Virtual Crossmatch Usage in Kidney Transplantation
J. E. Stanton¹, L. M. Rebellato², H. Pournik¹, J. E. Tuttle-Newhall¹, H. Jones¹, W. Irish¹, D. B. Leeser¹
¹Department of Surgery, East Carolina University, The Brody School of Medicine, Greenville, NC, ²Department of Pathology, East Carolina University, The Brody School of Medicine, Greenville, NC
*Purpose: The implementation of virtual crossmatching (VXM) into conventional protocols may reduce expenditures associated with organ allocation.*Methods: A single center retrospective analysis of the total…
2020 American Transplant Congress
Gene Expression Dynamics Demonstrate Perturbations in Innate and Adaptive Immunity in Kidney Transplantation Patients with Cytomegalovirus Viremia
R. Ahn, J. Schaenman, Z. Qian, V. Groysberg, M. Rossetti, A. Hoffmann, D. Gjertson, M. Deng, E. F. Reed
University of California Los Angeles, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) viremia and disease continues to cause significant morbidity and mortality in kidney transplant patients with clinical complications including organ rejection and death.…
2020 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) and Gene Expression Signatures of Antibody-Mediated Rejection (ABMR) May Improve Accuracy of ABMR Diagnosis (Dx)
H. Zhang¹, C. C. Nast², E. Huang³, N. Ammerman³, A. A. Vo³, S. C. Jordan³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Dd-cfDNA has a clinically meaningful association with early Dx of ABMR. Here, we evaluated dd-cfDNA measured prior to for-cause biopsies (Bx), and also measured…
2020 American Transplant Congress
Patient Reported Medication Nonadherence and Tolerability: Results of a Prospective Observational Study
D. Taber, N. Patel, K. Foster, F. Bartlett, C. Perez, H. Meadows, N. Pilch, A. Posadas, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Medication nonadherence (MNA) is a major contributor to late allograft loss in transplantation (txp). Immunosuppression therapy is highly effective at preventing rejection yet presents…