Articles tagged "Kidney transplantation"

2020 American Transplant Congress
A Single Centre Report of Renal Transplantation Against a Positive Crossmatch Due to HLA-DP Donor Specific Antibodies without Prior Antibody Removal
Y. Marie¹, T. Key², A. Halawa¹
¹Renal Transplantation, Sheffield Kidney Institute, Sheffield, United Kingdom, ²2.Department of Histocompatibility and Immunogenetics, Sheffield, United Kingdom
*Purpose: In renal transplantation, the clinical effects of donor specific antibodies (DSA) against HLA-DP are unclear. We report successful kidney transplants in three highly sensitised…
2020 American Transplant Congress
Post-Operative Opiate Utilization and Prescribing Patterns in Living Kidney Donors
E. Calderon¹, D. S. Ubl², C. Jadlowiec¹, P. Dean³, E. Castle⁴, P. Andrews⁴, B. Taner⁵, E. Habermann², A. K. Mathur¹
¹Transplant Surgery, Mayo Clinic, Phoenix, AZ, ²Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, ³Transplant Surgery, Mayo Clinic, Rochester, MN, ⁴Department of Urology, Mayo Clinic, Phoenix, AZ, ⁵Transplant Surgery, Mayo Clinic, Jacksonville, FL
*Purpose: Living kidney donors (LKDs) become exposed to opioids during routine post-surgical care, which may lead to adverse outcomes. and since there is an absence…
2020 American Transplant Congress
Factors Associated with Renal Graft Loss in Simultaneous Kidney-Heart Transplant Recipients in the UNOS Cohort
K. A. Agarwal¹, H. Patel¹, K. Almonte², F. Cardarelli¹, N. Agrawal¹
¹Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Medicine, Mount Auburn Hospital, Cambridge, MA
*Purpose: Simultaneous kidney and heart transplants (SKHT) are employed for patients with both end-stage heart failure and severely impaired kidney function. Renal outcomes in such…
2020 American Transplant Congress
Virtual XM Adversely Affects Access for Highly Sensitized African Americans Awaiting Renal Transplantation
P. T. Jindra¹, B. V. Murthy¹, C. Van Buren²
¹Surgery, Baylor College of Medicine, Houston, TX, ²Surgery, UT Medical School, Houston, TX
*Purpose: Recent UNOS policy proposals have changed kidney allocation from local Designated Service Areas (DSA) to geographic distribution areas of varying widths. Since crossmatch of…
2020 American Transplant Congress
Improved Outcomes Over the Past 13 Years in HIV Positive Kidney Transplant Recipients-A Single Center Experience
A. Mattiazzi¹, J. F. Camargo², S. Anjan², M. I. Morris², L. Abbo², J. Simkins², Y. Natori², K. Aoke³, A. Zilli³, R. Thurston³, M. Muldoon³, L. Preczewski³, L. J. Chen⁴, G. W. Burke⁴, G. Ciancio⁴, G. Guerra¹
¹Medicine. Division of Nephrology, University of Miami/Miami Transplant Institute, Miami, FL, ²Medine. Division of Infectious Disease, University of Miami/Miami Transplant Institute, Miami, FL, ³Miami Transplant Institute, Miami, FL, ⁴Surgery, University of Miami/Miami Transplant Institute, Miami, FL
*Purpose: Kidney transplantation in HIV positive recipients (HIV+) is the treatment of choice for renal failure in patients (P) who maintain CD4+ counts ≥ 200/mm3and…
2020 American Transplant Congress
Impact of Extended- versus Immediate-Release Tacrolimus on One-Year Development of De Novo DSA and Chronic Immune Activation in Kidney Transplantation (ASTOUND Study)
A. Wiseman¹, D. Kaufman², A. Patel³, D. Wojciechowski⁴, A. Tambur⁵, J. Kim⁶, J. Schwartz⁶
¹University of Colorado Hospital, Aurora, CO, ²University of Wisconsin, Madison, WI, ³Henry Ford Hospital, Detroit, MS, ⁴Massachusetts General Hospital, Boston, MA, ⁵Northwestern University, Chicago, IL, ⁶Astellas Pharma Global Development, Northbrook, IL
*Purpose: To compare, using an adaptive study design, the 1-year incidence of a novel two-part composite endpoint consisting of de novo donor-specific antibody (dnDSA) formation…
2020 American Transplant Congress
Glomerular Filtration Rate Based on Cystatin C Provides the Best Prediction of Cardiovascular Events and Mortality Compared to Measured GFR and Creatinine Based GFR in Kidney Transplant Recipients
L. Galapia¹, J. Lieske², A. Rule², H. Amer², N. Zhang¹, D. Butterfield¹, M. Keddis¹
¹Mayo Clinic, Scottsdale, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: GFR estimated by cystatin C (CysC) is a better predictor of cardiovascular (CV) events and mortality compared to eGFR by creatinine (Cr) in native…
2020 American Transplant Congress
Waitlist-Conditioned Transplant Rate is Not an Appropriate Metric for Benchmarking Access to Kidney Transplantation
D. Anderson, H. Qu, P. MacLennan, M. Mustian, R. Reed, A. C. Kale, B. Orandi, B. Shelton, V. Kumar, J. Locke, M. Hanaway
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Transplant rate is used as a primary metric of center performance as reported by the SRTR. However, the calculation of transplant rate can be…
2020 American Transplant Congress
Molecular Diagnosis and Risk Prediction in BK Virus Nephropathy: Discovery and Multicenter Validation of Novel Intragraft Gene Expression Signatures
B. Adam¹, Z. Kikic², Y. Bouatou³, J. Gueguen³, B. Robin³, G. Reid¹, H. Regele², M. Rabant³, A. Loupy³, M. Mengel¹
¹University of Alberta, Edmonton, AB, Canada, ²Medical University of Vienna, Vienna, Austria, ³Paris Transplant Group, Paris, France
*Purpose: Novel tools are needed to improve diagnosis and risk prediction in BK virus nephropathy (BKVN). This study aimed to assess the utility of intragraft…
2020 American Transplant Congress
Predictive Validity of Functional Status on Mortality in Adult Kidney Transplant Recipients
N. Chu, Z. Shi, D. Segev, M. McAdams Demarco
Johns Hopkins, Baltimore, MD
*Purpose: Frailty and disabilities, though not routinely measured, are highly prevalent in kidney transplant (KT) recipients and predict poor post-transplant outcomes. The Karnofsky Performance Scale…