Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Elucidating the Genetic Background of End Stage Renal Disease of Unknown Aetiology in Patients Listed for Kidney Transplantation
E. Leenen¹, B. Beck², A. Joerres¹, A. Weidemann¹
¹Department of Medicine I - Nephrology, Transplantation & Medical Intensive Care, Medical Center Cologne-Merheim, Cologne, Germany, ²Institute of Human Genetics University Hospital Cologne, Medical Center Cologne-Merheim, Cologne, Germany
*Purpose: The prevalence of end stage renal disease (ESRD) of unknown aetiology in adult patients accounts for almost 20% of all dialysis patients in Europe.…
2020 American Transplant Congress
The Influence of Donor Kidney to Recipient Body Weight Ratio on Long-Term Outcomes of Living-Donor Kidney Transplantation
N. Sato, Y. Kakuta, T. Kanzawa, K. Unagami, M. Okumi, H. Ishida, K. Tanabe
Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
*Purpose: We often experience the incompatibility in size between the kidney graft and recipient in living-donor kidney transplantation. This study evaluated the effect of the…
2020 American Transplant Congress
Technology Access, Use, and Intent among Kidney Transplant Candidates Vulnerable to Health Disparities
S. Smith¹, M. Keller², R. Seibert³, L. Kayler¹
¹Transplant, Transplant and Kidney Care Regional Center of Excellence, Erie County Medical Center, Buffalo, NY, ²Transplant, University at Buffalo, State University of New York, Department of Community Health and Health Behavior, Buffalo, NY, ³Transplant, University at Buffalo, State University of New York, Department of Epidemiology and Environmental Health, Buffalo, NY
*Purpose: Advances in eHealth have created opportunities to reach vulnerable populations, however, eHealth strategies could paradoxically increase health disparities if vulnerable individuals lack technology access…
2020 American Transplant Congress
Clazakizumab (Anti-IL-6) Induces Foxp3+ Tregs in Highly HLA Sensitized Patients Desensitized for HLAi Transplantation (NCT03380962)
S. C. Jordan, S. Ge, N. Ammerman, M. Toyoda, E. Huang, A. Peng, R. Najjar, S. Sethi, S. Williamson, C. Myers, K. Lim, J. Choi, A. Vo
Cedars Sinai Medical Ctr, West Hollywood, CA
*Purpose: Interleukin-6 is an important inflammatory cytokine. In addition, it acts as a growth factor for B-cells, plasma cells and Th17 cells, inhibiting FoxP3+ Treg…
2020 American Transplant Congress
Infectious Complications in Elderly Kidney Transplant Recipients Undergoing Desensitization
S. Sethi, R. Najjar, A. Peng, A. Vo, S. Jordan, E. Huang
Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Data is limited on the impact of desensitization on infectious complications in elderly kidney transplant (KT) recipients. We examined infectious complications in elderly KT…
2020 American Transplant Congress
Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion
G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
2020 American Transplant Congress
Microvascular Inflammation without DSA or C4d: An Orphan Category in Banff Classification with Intense Capillaritis and Cytotoxic T-Cell Infiltration
A. Buxeda¹, L. Llinàs-Mallol², J. Gimeno³, C. Arias-Cabrales¹, C. Burballa¹, D. Redondo-Pachón¹, D. Raïch-Regué², M. Pérez-Sáez¹, J. Pascual¹, M. Crespo¹
¹Nephrology Department, Hospital del Mar, Barcelona, Spain, ²Nephrology Department, IMIM - Institute Hospital del Mar for Medical Research, Barcelona, Spain, ³Pathology Department, Hospital del Mar, Barcelona, Spain
*Purpose: Antibody-mediated rejection (ABMR) associated with donor-specific HLA antibodies (DSA) is the leading cause of late allograft failure after kidney transplantation. Microvascular inflammation (MVI) without…
2020 American Transplant Congress
Investigation of Il35 Expressing Regulatory B Cells in Tolerance of Kidney Transplantation
J. A. Sullivan, J. H. Fechner, E. Jankowska-Gan, W. J. Burlingham, D. B. Kaufman
Surgery, University of Wisconsin, Madison, WI
*Purpose: The development and maintenance of peripheral tolerance is required for long term success of solid organ transplantation without immuno-suppressive drugs. Using a novel, post-transplant,…
2020 American Transplant Congress
Trends in Living Kidney Donation in the United States
A. Ferzola, Y. Yu, A. B. Massie, D. L. Segev, M. L. Henderson
Johns Hopkins University, Baltimore, MD
*Purpose: After peaking in 2014, the number of LKDTs per year dropped substantially in the US despite an increasing waitlist. However, trends in the KAS…
2020 American Transplant Congress
A Single-Center Analysis of Using Allele-Level 11 HLA Loci Information on cPRA and Organ-Allocation Points in Kidney Transplant Candidates
C. Maguire¹, P. Muluhngwi¹, E. Kransdorf², L. Gragert³, A. R. Tambur¹
¹Northwestern University, Chicago, IL, ²Cedars-Sinai Heart Institute, Beverly Hills, CA, ³Tulane University, New Orleans, LA
*Purpose: Calculated panel reactive antibodies (cPRA) is used by the United Network for Organ Sharing (UNOS) to quantify degree of HLA sensitization and assign priority…