Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Utilization of Kidneys from Deceased Donors with Positive Hepatitis C Nucleic Acid Amplification Testing (HCV NAT+)
K. L. King, S. A. Husain, S. Mohan
Columbia University, New York, NY
*Purpose: With modern direct-acting antiviral agents, transplantation of kidneys from HCV NAT+ deceased donors for recipients with or without HCV has expanded the kidney supply.…
2020 American Transplant Congress
Financial Feasibility of a Culturally Competent and Linguistically Congruent Hispanic Kidney Transplant Program
E. Gordon¹, A. Wang¹, G. McNatt¹, M. Abecassis², J. Caicedo¹
¹Northwestern U Feinberg Sch of Medicine, Chicago, IL, ²University of Arizona, Tuscon, AZ
*Purpose: Relative to their representation on the waitlist, Hispanics/Latinos received significantly fewer LDKTs than non-Hispanic Whites in 2018: 5.0% versus 12.2%. In 2006, Northwestern Medicine…
2020 American Transplant Congress
Single Cell RNA Transcriptomics to Further the Precision Transplantation Medicine Approaches in Kidney Allograft Recipients
H. Suryawanshi, H. Yang, M. Lubetzky, S. Seshan, T. Tuschl, M. Suthanthiran, T. Muthukumar
Weill Cornell Medicine, New York, NY
*Purpose: Test the hypothesis that single cell RNA transcriptomics will further the precision transplantation medicine approaches and address important conundrums in clinical transplantation.*Methods: We studied…
2020 American Transplant Congress
Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, I. Yakubu¹, S. Paluri¹, A. Chachar¹, J. Chang², I. Moinuddin¹, L. Kamal¹, M. Levy¹, C. Bhati¹, A. King¹, P. Kimball¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²ATAGC, Edmonton, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. Basic and…
2020 American Transplant Congress
Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: Update on the Take It Trial
E. Yoon¹, S. Hurr¹, L. Curtis¹, D. Ladner², S. Nair³, M. S. Wolf¹
¹Center for Applied Health Research on Aging (CAHRA), Northwestern University Feinberg School of Medicine, Chicago, IL, ²Surgery, Northwestern Medicine, Chicago, IL, ³Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ
*Purpose: In 2017, the TAKE IT trial began its evaluation of a multifaceted, technology-enabled, transplant center-based intervention to monitor medication adherence behaviors among Kidney Transplant…
2020 American Transplant Congress
ATHENA – Patient and Allograft Outcome Differences after Kidney Transplantation – Germany vs. France
F. Thaiss¹, C. Sommerer¹, B. Suwelack¹, D. Dragun¹, I. A. Hauser¹, O. Witzke¹, C. Hugo¹, P. Schenker¹, N. Kamar², P. Merville², I. Kroeger³, M. Junge³, B. Nashan¹
¹Athena, Study Group, Germany, ²Athena, Study Group, France, ³Novartis Pharma GmbH, Nürnberg, Germany
*Purpose: In the ATHENA trial [NCT01843348], efficacy and safety of everolimus in combination with tacrolimus [EVR+TAC] or cyclosporine A [EVR+CyA] vs. TAC and mycophenolic acid…
2020 American Transplant Congress
The Impact of Cold Ischaemia Time on Living Donor Kidney Transplantation Outcomes
S. C. van de Laar¹, M. Robb², R. Hogg², V. Papalois¹, F. J. Dor¹
¹Department of Surgery & Cancer, Imperial College London, Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, White City, London, United Kingdom, ²NHS Blood and Transplant, Bristol, United Kingdom
*Purpose: Living donor KTx (LDKT) provides the best option for patients with end-stage kidney disease (ESKD). ESKD patients who have an incompatible living donor still…
2020 American Transplant Congress
Analysis of 1000 Protocol Kidney Biopsies: Complications, Benefits, and Predictive Potential of Prior Sensitization
M. Eslami¹, J. Patel², S. Karzai¹, D. T. Collins¹, C. Liu¹, J. Jonsson¹, R. Wali¹, J. B. Piper¹
¹Surgery, Inova Fairfax Hospital, Falls Church, VA, ²General Surgery, Pennsylvania State University, State College, PA
*Purpose: Protocol biopsy of kidney transplants can allow for early recognition of treatable findings, both immunologic and non-immunologic. This comes with the risk of biopsy…
2020 American Transplant Congress
Renal Allograft Surveillance with Allospecific T-cytotoxic Memory Cells Which Express CD154
V. Rohan, A. Alqassieh, N. Patel, K. Soliman, V. Rao
Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Allo-antigen-specific T-cytotoxic memory cells (TcM) which express CD40 ligand (CD154) in overnight lymphocyte co-culture are strongly associated with acute cellular rejection (ACR) seen in…
2020 American Transplant Congress
Optimal Recipient Selection and Surgical Complications in Dual Kidney Transplantation
S. Patel¹, S. Chang², R. Sussman³, R. Plews¹, R. Lopez-Soler⁴, D. Conti¹
¹Kidney and Pancreas Transplantation, Albany Medical Center, Albany, NY, ²Nephrology and Transplantation, University at Buffalo, Buffalo, NY, ³Center for Donation and Transplantation, Albany Medical Center, Albany, NY, ⁴Renal Transplant Program, Hines VA Medical Center, Chicago, IL
*Purpose: Kidney allocation has recently been modified to allow enhanced utilization of dual kidney transplants (DKT) to reduce organ discards. This study evaluates surgical complications…