Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Single Cell RNA Sequencing of Murine Kidney Allografts Identifies Macrophage Gene Signature Associated with Acute Rejection
A. Dangi¹, N. Natesh², M. Monal¹, J. Wang³, X. Shen², X. Luo¹
¹Nephrology/Medicine, Duke University, Durham, NC, ²Biomedical Engineering, Duke University, Durham, NC, ³Surgery, Duke University, Durham, NC
*Purpose: Evaluating kidney allografts using single cell RNA sequencing (scRNAseq) can provide a comprehensive qualitative and quantitative gene expression data on thousands of individual cells.…
2020 American Transplant Congress
Long-Term Outcomes of Single Kidney Transplants from Small Pediatric Donors
S. Sultan, J. Son, M. Aull, R. Craig-Schapiro, A. Watkins, S. Kapur
Weill Cornell Medical College, New York, NY
*Purpose: On September 5th, 2019, UNOS implemented an important policy change in the allocation of kidneys from small pediatric donors. In trying to balance achieving…
2020 American Transplant Congress
1 -Year Protocol Biopsies in Pediatric Kidney Transplant Children: Are Unfavorable Histological Lesions Related to No Adherence?
M. L. Monteverde¹, J. M. Velasco¹, V. Solernou², J. P. Ibanez¹, C. Cernadas³, A. B. Chaparro⁴, Y. L. Marcos⁵
¹Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ²Pathology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ³Teaching and Investigation, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ⁴Nephrology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ⁵Hemoteraphy, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina
*Purpose: In adults with kidney transplantation (KT), histological findings in surveillance biopsies at 1-year post KT are independent correlate to short and long-term graft survival.…
2020 American Transplant Congress
Delayed Introduction of Mammalian Inhibitors of Rapamycin (mTOR) Post Kidney Transplantation Might Avoid the Chronic Nephrotoxicity of Calcineurin Inhibitors. Herein We Are Reporting an Eight-Years Single Center Experience of mTOR-Based Immunosuppression Regimen in Comparison with Cyclosporin-Based Regimen
W. A. Hassan¹, H. M. Tawfik²
¹Medicine-Nephrology, University of Tennessee Health Science Center, Memphis, TN, ²Medicine-Nephrology, Minia Nephrology Hospital, Minia University, Minia, Egypt
*Purpose: Delayed introduction of mTOR inhibitors post kidney transplantation might avoid the chronic nephrotoxicity of CNI: eight-years single center experience.*Methods: This is a retrospective analysis…
2020 American Transplant Congress
Potential Cost-Savings Associated with ANG-3777 for the Treatment of Delayed Graft Function in Kidney Transplantation
M. Cooper¹, T. Mayne², T. Kauf³, M. Gargano³, K. Freemyer³
¹Medstar Georgetown Transplant Institute, Washington, DC, ²Angion Biomedica Corp, San Francisco, CA, ³Genesis Research, Hoboken, NJ
*Purpose: We created a medical cost offset model based upon the results of a Phase 2, double-blind, randomized controlled trial of ANG-3777, a hepatocyte growth…
2020 American Transplant Congress
Kidney Transplantation and Short Bowel Syndrome: Outcomes and Challenges
E. Abou Diwan¹, A. Patel², N. Elias³, K. Safa³
¹American University of Beirut, Beirut, Lebanon, ²Nephrology, Brigham and Women's Hospital, Boston, MA, ³Transplant Center, Massachusetts General Hospital, Boston, MA
*Purpose: Among patients with short bowel syndrome (SBS), kidney disease is highly prevalent due to volume depletion, crystal nephropathies, and many other reasons. Kidney transplantation…
2020 American Transplant Congress
Comparison of Anti-Thymocyte Globulin and Alemtuzumab as Induction Therapy in Older Kidney Transplant Recipients
M. Chaung, E. Hollinger, M. Brokhof, N. Alvey, L. Lineberger, N. Kenyon
Rush University Medical Center, Chicago, IL
*Purpose: The purpose of this study is to evaluate the safety and efficacy of induction with either anti-thymocyte globulin (ATG) (total dose 5 mg/kg) or…
2020 American Transplant Congress
The Impact of Pre-Existing and New Onset Diabetes on Healthcare Utilization Following Kidney Transplantation
D. Taber, N. Pilch, N. Patel, H. Perkins, K. Foster, C. Perez, F. Bartlett, A. Posadas, H. Meadows, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Diabetes (DM) represents a global epidemic; it is the leading cause of ESRD in the US and a predominant etiology for kidney transplantation (KTX).…
2020 American Transplant Congress
Predictability of Eplet Mismatch to Acute Rejection in Low Level HLA Antigen Mismatched Kidney Transplantation: Analysis of Korean Organ Transplantation Registry (KOTRY) Data
J. Jeong¹, Y. Hong¹, Y. Park², I. Park³, J. Park⁴, D. Chae⁵, J. Yang⁶, C. Ahn⁵, B. G. Park⁷
¹Seoul National University Bundang Hospital, Seongnam, Korea, Republic of, ²Gachon University, Incheon, Korea, Republic of, ³Ajou University School of Medicine, Suwon, Korea, Republic of, ⁴Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ⁵Seoul National University College of Medicine, Seoul, Korea, Republic of, ⁶Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Korea University Guro Hospital, Seoul, Korea, Republic of
*Purpose: Epitope matching has been shown to better predict allograft survival and development of de novo donor specific antibodies. In previous study, the number of…
2020 American Transplant Congress
Ureteral Complications Post Kidney Transplantation – Incidence and Preferred Treatment Modality
R. Patten¹, H. Mustafa², S. Desai³, J. Buggs⁴, E. Rogers⁴, A. Kumar¹, V. Bowers⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of South Florida, Tampa, FL, ³University of Tampa, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: The primary objective of this study was to evaluate the incidence of ureteral complications at a single transplant center. A secondary objective was to…