Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Belatacept Combined with BTLA Prolong Allogeneic Kidney Graft Survival and Inhibited Acute Rejection after Kidney Transplantation
H. Zhang, Z. Wang, J. Zhang, Z. Han, J. Tao, H. Chen, L. Sun, R. Tan, M. Gu
Jiangsu Province Hospital, Nanjing, China
*Purpose: Belatacept as a high-affinity variant of CTLA-4Ig, has been applied into kidney transplantation to against acute rejection. However, adoption of Belatacept has been limited…
2020 American Transplant Congress
Alemtuzumab and Associated Infectious and Transplant Outcomes in Renal Re-Transplant Patients
T. N. Harris
The Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: The purpose of this study was to evaluate infectious and transplant outcomes exclusively in renal re-transplant patients who had received alemtuzumab for induction therapy.*Methods:…
2020 American Transplant Congress
The Eplet-Mismatch Landscape in Kidney Patients and Deceased Donors in British Columbia
J. Tran¹, O. Gunther², J. Lan¹, M. Kadatz¹, R. Sapir-Pichhadze³, P. A. Keown¹
¹University of British Columbia, Vancouver, BC, Canada, ²Gunther Analytics, Vancouver, BC, Canada, ³McGill University, Montreal, QC, Canada
*Purpose: Minimizing quantitative donor/recipient mismatch at the HLA epitope level may optimize graft outcomes in renal transplantation, but the degree to which optimal matching can…
2020 American Transplant Congress
Risk Factors for Adverse Clinical Outcomes amongst Renal Transplant Candidates Undergoing Screening Angiography for Coronary Artery Disease
M. Shah¹, A. Yung¹, J. Ebinger¹, J. Mirocha², E. Huang³, D. Geft¹, A. Peng³, B. Azarbal¹
¹Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Department of Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Patient’s with ESRD undergoing evaluation for kidney transplantation routinely undergo screening for coronary artery disease (CAD). Screening recommendations in this population differ between ACC/AHA…
2020 American Transplant Congress
CD38 Antibody Daratumumab for the Treatment of Chronic Antibody-Mediated Kidney Allograft Rejection
K. Doberer¹, J. Kläger², G. A. Gualdoni¹, K. Mayer¹, F. Eskandary¹, H. Agis³, T. Reiter¹, R. Reindl-Schwaighofer¹, M. Wahrmann¹, G. Cohen¹, H. Haslacher⁴, G. Bond¹, I. Simonitsch-Klupp⁵, I. Farkash⁶, P. Halloran⁷, G. A. Böhmig¹
¹Department of Medicine III, Medical University of Vienna, Vienna, Austria, ²Dept. of Clin. Pathology, Medical University of Vienna, Vienna, Austria, ³Department of Medicine I, Medical University of Vienna, Vienna, Austria, ⁴Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria, ⁵Department of Pathology, Medical University of Vienna, Vienna, Austria, ⁶Dept. of Pathology, University of Michigan, Ann Arbor, MI, ⁷Alberta Transplant Applied Genomics Centre, ATAGC, University of Alberta, Edmonton, AB, Canada
*Purpose: Late antibody-mediated rejection (ABMR) is a major cause of transplant failure. Potential therapeutic targets are plasma cells (PC) and natural killer (NK) cells expressing…
2020 American Transplant Congress
Frailty and Its Implications for Early Post-Transplant Outcomes in Kidney Transplant Recipients
J. Kim, P. Chen, M. Minkovich, O. Famure, Y. Li
Toronto General Hospital, Toronto, ON, Canada
*Purpose: Frailty, a measure of physiologic reserve, is associated with poor early outcomes, like early hospital readmission (EHR) and delayed-graft function (DGF) in kidney transplant…
2020 American Transplant Congress
Assessment of Infectious Complications Following ABO-Blood Group Incompatible Renal Transplant
J. Banbury¹, T. Loosier¹, C. Lin², K. Gutierrez¹
¹University of Alabama at Birmingham Hospital, Birmingham, AL, ²Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL
*Purpose: In response to the ongoing organ shortage, ABO-incompatible (ABOi) renal transplant (RT) provides an alternative option for patients with end-stage kidney disease. Literature suggests…
2020 American Transplant Congress
Effect of Everolimus and Reduced Calcineurin Inhibitors on Biopsy Proven BK Virus Associated Nephropathy
Z. S. Zaky, M. Spinner, B. Stephany, S. Nurko, R. Fatica, J. Augustine, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that contributes to allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin inhibitors…
2020 American Transplant Congress
Assessment of HEALTh LIteracy on MEdication ADheREnce and Graft Outcomes in KIdney Transplant Recipients (Hallmark)
M. Leung¹, A. Dhanda², S. Kwan³, A. Zienkiewicz³, E. Waters³, N. Wood³, L. Young³, C. Bannon³
¹Pharmacy, St. Paul's Hospital, Vancouver, BC, Canada, ²Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ³Nephrology, St. Paul's Hospital, Vancouver, BC, Canada
*Purpose: Upon successful kidney transplantation, many patients have difficulty adhering to their new immunosuppression medication regimens. Previous studies have established low health literacy to be…
2020 American Transplant Congress
Assessment of the Usefulness of Urine Signature to Differentiate Acute Rejection in a Prospective Kidney Transplantation Cohort
J. Seo¹, S. Jung², J. Moon², K. Jeong³, C. Kim⁴, B. Chung⁵, J. Park⁶, Y. Kim⁷, S. Lee²
¹Department of Core Research Laboratory, Medical Science Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ²Department of Internal Medicine, Division of Nephrology, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ³Department of Internal Medicine, Division of Nephrology, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Division of Nephrology, Kyung-pook National University School of Medicine, Daegu, Korea, Republic of, ⁵Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ⁶Department of Internal Medicine, Sungkyunkwan University, Samsung Hospital, College of Medicine, Seoul, Korea, Republic of, ⁷Department of Internal Medicine, Division of Nephrology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea, Republic of
*Purpose: Despite many biomarker studies in the field of transplantation, development and validation of noninvasive molecular assays to diagnose disease and monitor immune activity is…