Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Analyzing Causes for Death-Censored Graft Failure
M. Mayrdorfer, L. Liefeldt, N. Lachmann, W. Düttmann-Rehnolt, F. Halleck, M. G. Naik, P. Glander, K. Budde
Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Since it has been proposed that several causes could contribute to graft loss (GL), we analyzed graft failure in our center and attributed a…
2020 American Transplant Congress
Normothermic Ex-Vivo Kidney Perfusion is Superior to Anoxic and Oxygenated Hypothermic Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts
L. Mazilescu¹, M. Kaths², P. Urbanellis¹, M. Hamar³, T. Goto¹, I. Linares-Cervantes¹, Y. Noguchi¹, A. Konvalinka¹, A. Ghanekar¹, D. Bagli⁴, R. John⁵, L. Robinson⁶, M. Selzner¹
¹Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada, ²Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany, ³Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ⁴Departments of Surgery(Urology)&Physiology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Laboratory Medicine & Pathobiology, Toronto General Hospital, Toronto, ON, Canada, ⁶Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: To increase the donor pool, better preservation strategies for the storage of marginal kidney grafts are crucial. Currently, kidney grafts are either stored on…
2020 American Transplant Congress
Creation of a Low-Cost Kidney Transplant Surgery Simulator and Survey of its Utility for Education
V. Melkonian, T. Huy, C. Varma, M. Nazzal, H. Randall, M. Nguyen
Department of Surgery, Saint Louis University, Saint Louis, MO
*Purpose: Surgical skills education in transplant surgery is challenging as center-specific outcomes are scrutinized and trainees’ exposure to the sub-specialty is decreasing. Simulation could overcome…
2020 American Transplant Congress
Use of tCRM to Aid Diagnosis of Allograft Rejection in Kidney Transplantation
A. Zarinsefat¹, J. Liberto¹, I. Damm¹, C. Ramirez², J. Guerra², J. Alberu², M. Sarwal¹
¹University of California San Francisco, San Francisco, CA, ²Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico
*Purpose: To apply an unbiased, quantitative, molecular profiling score for graft inflammation using standardized assays, in the context of a prospective clinical trial in kidney…
2020 American Transplant Congress
Clinical Significance of C4d and HLA-DSA on Post-Transplant Clinical Outcomes in Kidney Transplant Recipients with Antibody-Mediated Rejection
W. Park, O. Kwon, Y. Kim, J. Paek, K. Jin, S. Park, S. Han
Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institute, Daegu, Korea, Republic of
*Purpose: The clinicopathological diagnosis of rejection after kidney transplantation (KT) was well defined by Banff classification. In the diagnosis of antibody-mediated rejection (AMR), the presence…
2020 American Transplant Congress
HCV Viremic Kidneys for Uninfected Recipients with DAA Treatment Offers Sustained Virologic Response
J. Torabi, A. Montal, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, E. Akalin, J. Melvin, M. Kinkhabwala, S. Greenstein, J. P. Rocca, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: Development of direct acting anti-viral medications (DAA) have offered cure rates for hepatitis C infection (HCV) approaching 100%. This has provided the ability to…
2020 American Transplant Congress
Impact of Pregnancy on Kidney Transplant Recipients: A Propensity Score-Matched Study
T. Abe, A. Taniguchi, M. Kawamura, S. Nakazawa, T. Kato, R. Imamura, N. Nonomura
Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan
*Purpose: This study aimed to evaluate whether the experience of pregnancy and delivery would be associated with poor maternal outcome among kidney transplant recipients.*Methods: A…
2020 American Transplant Congress
Assessment of Time to Therapeutic Tacrolimus Levels Following Renal Transplantation in a Non-Weight-Based Dosing Model
J. Banbury¹, A. Dodson¹, C. Lin², K. Gutierrez¹
¹University of Alabama at Birmingham Hospital, Birmingham, AL, ²Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL
*Purpose: The optimal initial dose for tacrolimus (TAC) after renal transplant (RT) remains controversial with limited evidence comparing weight-based and conservative strategies. Recent literature suggests…
2020 American Transplant Congress
Does Transplantation of Hepatitis C Infected Kidneys Into Uninfected Recipients Cause Hepatitis C-Associated Kidney Injury?
R. H. Naik, S. Shawar, R. C. Forbes, H. Schaefer, D. Shaffer, M. Rossi, V. Imperio, B. P. Concepcion, M. Kapp
Vanderbilt University Medical Center, Nashville, TN
*Purpose: With increasing utilization of Hepatitis C infected (HCV+) kidneys for transplantation into uninfected (HCV-) recipients, there is concern for the development of HCV-associated kidney…
2020 American Transplant Congress
The Effect of B Cell Depletion Therapies on Preformed Xenoantibodies in Transplant Recipient
S. Yeh¹, N. A. Wilson², A. Djamali², R. Redfield³
¹Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, ²Medicine/Nephrology, University of Wisconsin-Madison, Madison, WI, ³Surgery, University of Wisconsin-Madison, Madison, WI
*Purpose: To assess the effect of B cell depletion therapies on preformed xenoantibodies in transplant recipient. Preformed xenoantibodies are a significant barrier to successful xenotransplantation.…