Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Exposure to Tacrolimus Trough Levels Below 6ng/ml During the First Year is Associated with Inferior Kidney Graft Survival
T. Agur, B. Rozen-Zvi, R. Rahamimov
Department of Nephrology and Hypertension, Rabin Medical Center, Petah Tikva, Israel
*Purpose: Accumulating data indicates that sub-therapeutic levels of calcineurin inhibitors are associated with long-term graft loss. However, while widely used tacrolimus (TAC) was shown to…
2020 American Transplant Congress
Continuous Improvement in Long Term Survival of Kidney Transplants Over the Past Two Decades
E. D. Poggio¹, S. Arrigain², A. Wee³, D. C. Brennan⁴, J. D. Schold²
¹Nephrology, Cleveland Clinic, Cleveland, OH, ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ³Urology, Cleveland Clinic, Cleveland, OH, ⁴Nephrology, Johns Hopkins, Baltimore, MD
*Purpose: Short-term kidney transplant (KTx) graft survival has improved during past decades, but prior research has indicated stagnation or minimally improving long-term outcomes. We studied…
2020 American Transplant Congress
Ranking Eplet Mismatches as Predictors of Graft Failure
W. Zhang¹, H. Mohammadhassanzadeh¹, K. Oualkacha², H. Gebel³, W. Klement⁴, R. Sapir-Pichhadze¹
¹McGill University, Montreal, QC, Canada, ²UQAM, Montreal, QC, Canada, ³Emory University Hospital, Atlanta, GA, ⁴Canadian Blood Services, Ottawa, ON, Canada
*Purpose: Donor:recipient matching at the level of sequence defined HLA targets (eplets) is being promoted as a biologically sound strategy to prevent graft failure. Because…
2020 American Transplant Congress
Patterns of Belatacept Use and Risk of Post-Transplant Lymphoproliferative Disorder (PTLD) in US Kidney Transplant Recipients – Analysis of Organ Procurement and Transplantation Network (OPTN) Database
W. S. Cherikh¹, T. Kou², J. Foutz¹, A. Gomez-Caminero²
¹United Network for Organ Sharing (UNOS), Richmond, VA, ²Bristol-Myers Squibb, Princeton, NJ
*Purpose: Belatacept, a selective T-cell costimulation blocker, was approved in 2011 for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients. PTLD…
2020 American Transplant Congress
The Learning Curve for Pure Laparoscopic Robotic Kidney Transplantation: An Analysis of Outcomes of the First 80 Consecutive Cases at a High-Volume Transplant Center
F. Tinney Jr.¹, J. Stracke², T. Ivanics¹, A. Elsabbagh¹, J. Denny¹, D. Kim¹, L. Malinzak¹, A. Yoshida¹
¹Transplant Institute, Henry ford Hospital, Detroit, MI, ²Transplant Surgery, Metro Health Hospital, Wyoming, MI
*Purpose: Robotic surgery is increasingly used in complex operations, including living-donor kidney transplantation. At this time, knowledge of the number of cases required to attain…
2020 American Transplant Congress
Impact of Eplet Mismatches on the Risk of Graft Loss: Not All Eplets are Created Equal
H. Mohammadhassanzadeh¹, W. Klement², H. Gebel³, B. Foster⁴, P. Keown⁵, K. Oualkacha⁶, R. Sapir-Pichhadze¹
¹Medicine, McGill University, Montreal, QC, Canada, ²Organ Donation and Transplantation, Canadian Blood Services, Ottawa, ON, Canada, ³Emory University Hospital, Atlanta, GA, ⁴Montreal Children's Hospital, Montreal, QC, Canada, ⁵Medicine, University of British Columbia, Vancouver, BC, Canada, ⁶Université du Québec À Montréal, Montreal, QC, Canada
*Purpose: To mitigate risks related to HLA incompatibility, we assessed whether some unique sequence defined HLA targets (eplets) are associated with graft failure while others…
2020 American Transplant Congress
Comparison of Clinical Characteristics and Outcomes of Early Antibody-Mediated Rejection and Late Antibody-Mediated Rejection after Kidney Transplantation
G. Chen, Z. Wu, C. Wang, X. Liu, Q. Li, L. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Antibody-mediated rejection(AMR) is a major risk factor for graft loss after kidney transplantation. Some AMR appeared within 6 months after kidney transplant, that we…
2020 American Transplant Congress
Impact of Enhanced Recovery after Surgery Protocols on Robotic Living Kidney Donor Outcomes: A Single Center Experience
B. Ruch, A. Sharma, J. Amery, C. Bhati, A. Khan, A. Cotterell, M. Scott, M. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Traditional management of living donor nephrectomies includes intraoperative volume loading to maintain renal perfusion and urine output. Recently our center initiated fluid restriction as…
2020 American Transplant Congress
GLP1-RAs, SGLT2i Are Underutilized in Kidney Transplant Recipients with Diabetes Mellitus and Obesity
M. Stumpf, S. A. Dar, S. Rao, A. Doyle
University of Virginia, Charlottesville, VA
*Purpose: There is little research describing differences in use of antidiabetic medications amongst obese, diabetic patients with or without a history of kidney transplant. More…
2020 American Transplant Congress
Efficacy and Safety of Pre-Emptive Plasma Exchange and Rituximab in Prevention of Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation in High-Risk Patients
D. Christiadi, R. Charif, A. Kousios, M. Loucaidou
Imperial College Kidney and Transplant Center, Hammersmith Hospital, London, United Kingdom
*Purpose: Focal segmental glomerulosclerosis (FSGS) is considered the leading cause of nephrotic syndrome in the adult population. Following kidney transplantation (KT), the recurrence rate of…