Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Frailty Predicts Increased Length of Stay after Kidney Transplantation: An Implementation Study
J. Schaenman, B. Hale-Durbin, C. Lee, N. Ventigan, S. Jaladanki, L. Shih, B. Abdalla, R. Ahn, S. Chang, M. Dunbar-Forrest, H. A. Gritsch, G. Danovitch, D. Goldwater
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Our objective was to implement a standardized an assessment of physical frailty and other aging-associated syndromes during routine evaluation of kidney transplant candidates over…
2020 American Transplant Congress
Transmission of Synovial Sarcoma by a Single Multiorgan Donor to Three Solid Organ Transplant Recipients
J. Zhang, J. Lin, Y. Tian
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: To report 3 cases of donor-derived synovial sarcoma (SS) by a single multiorgan donor in China.*Methods: SS was diagnosed by the presence of SS18…
2020 American Transplant Congress
Immune Checkpoint Inhibitor Use in Kidney Transplant Recipients: Rejection Risk, Prevention and Transcriptional Signature in Allograft
N. Murakami¹, G. Reid², A. Weins¹, B. Adam², M. Mengel², L. Riella¹
¹Brigham and Women's Hospital, Boston, MA, ²University of Alberta, Edmonton, AB, Canada
*Purpose: Immune checkpoint inhibitor (ICI) use has changed the landscape of cancer treatment. Several cases of acute rejection in use of ICI have been reported,…
2020 American Transplant Congress
Health Mindsets Can Influence Psychosocial Ratings in Pediatric Renal Transplant Patients
R. Wright, A. Gallo, L. Maestretti, C. Mueller
Surgery, Stanford University, Stanford, CA
*Purpose: There is a large body of research which shows psychological states can influence health and behavioral outcomes, yet in clinical practice, psychosocial states are…
2020 American Transplant Congress
Single Cell RNA Sequencing of Murine Kidney Allografts Identifies Macrophage Gene Signature Associated with Acute Rejection
A. Dangi¹, N. Natesh², M. Monal¹, J. Wang³, X. Shen², X. Luo¹
¹Nephrology/Medicine, Duke University, Durham, NC, ²Biomedical Engineering, Duke University, Durham, NC, ³Surgery, Duke University, Durham, NC
*Purpose: Evaluating kidney allografts using single cell RNA sequencing (scRNAseq) can provide a comprehensive qualitative and quantitative gene expression data on thousands of individual cells.…
2020 American Transplant Congress
Long-Term Outcomes of Single Kidney Transplants from Small Pediatric Donors
S. Sultan, J. Son, M. Aull, R. Craig-Schapiro, A. Watkins, S. Kapur
Weill Cornell Medical College, New York, NY
*Purpose: On September 5th, 2019, UNOS implemented an important policy change in the allocation of kidneys from small pediatric donors. In trying to balance achieving…
2020 American Transplant Congress
1 -Year Protocol Biopsies in Pediatric Kidney Transplant Children: Are Unfavorable Histological Lesions Related to No Adherence?
M. L. Monteverde¹, J. M. Velasco¹, V. Solernou², J. P. Ibanez¹, C. Cernadas³, A. B. Chaparro⁴, Y. L. Marcos⁵
¹Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ²Pathology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ³Teaching and Investigation, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ⁴Nephrology, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina, ⁵Hemoteraphy, Hospital de Pediatria JP Garrahan, Buenos Aires, Argentina
*Purpose: In adults with kidney transplantation (KT), histological findings in surveillance biopsies at 1-year post KT are independent correlate to short and long-term graft survival.…
2020 American Transplant Congress
Delayed Introduction of Mammalian Inhibitors of Rapamycin (mTOR) Post Kidney Transplantation Might Avoid the Chronic Nephrotoxicity of Calcineurin Inhibitors. Herein We Are Reporting an Eight-Years Single Center Experience of mTOR-Based Immunosuppression Regimen in Comparison with Cyclosporin-Based Regimen
W. A. Hassan¹, H. M. Tawfik²
¹Medicine-Nephrology, University of Tennessee Health Science Center, Memphis, TN, ²Medicine-Nephrology, Minia Nephrology Hospital, Minia University, Minia, Egypt
*Purpose: Delayed introduction of mTOR inhibitors post kidney transplantation might avoid the chronic nephrotoxicity of CNI: eight-years single center experience.*Methods: This is a retrospective analysis…
2020 American Transplant Congress
Potential Cost-Savings Associated with ANG-3777 for the Treatment of Delayed Graft Function in Kidney Transplantation
M. Cooper¹, T. Mayne², T. Kauf³, M. Gargano³, K. Freemyer³
¹Medstar Georgetown Transplant Institute, Washington, DC, ²Angion Biomedica Corp, San Francisco, CA, ³Genesis Research, Hoboken, NJ
*Purpose: We created a medical cost offset model based upon the results of a Phase 2, double-blind, randomized controlled trial of ANG-3777, a hepatocyte growth…
2020 American Transplant Congress
Kidney Transplantation and Short Bowel Syndrome: Outcomes and Challenges
E. Abou Diwan¹, A. Patel², N. Elias³, K. Safa³
¹American University of Beirut, Beirut, Lebanon, ²Nephrology, Brigham and Women's Hospital, Boston, MA, ³Transplant Center, Massachusetts General Hospital, Boston, MA
*Purpose: Among patients with short bowel syndrome (SBS), kidney disease is highly prevalent due to volume depletion, crystal nephropathies, and many other reasons. Kidney transplantation…