Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Utilization of Kidneys from Deceased Donors with Positive Hepatitis C Nucleic Acid Amplification Testing (HCV NAT+)
K. L. King, S. A. Husain, S. Mohan
Columbia University, New York, NY
*Purpose: With modern direct-acting antiviral agents, transplantation of kidneys from HCV NAT+ deceased donors for recipients with or without HCV has expanded the kidney supply.…
2020 American Transplant Congress
Financial Feasibility of a Culturally Competent and Linguistically Congruent Hispanic Kidney Transplant Program
E. Gordon¹, A. Wang¹, G. McNatt¹, M. Abecassis², J. Caicedo¹
¹Northwestern U Feinberg Sch of Medicine, Chicago, IL, ²University of Arizona, Tuscon, AZ
*Purpose: Relative to their representation on the waitlist, Hispanics/Latinos received significantly fewer LDKTs than non-Hispanic Whites in 2018: 5.0% versus 12.2%. In 2006, Northwestern Medicine…
2020 American Transplant Congress
Single Cell RNA Transcriptomics to Further the Precision Transplantation Medicine Approaches in Kidney Allograft Recipients
H. Suryawanshi, H. Yang, M. Lubetzky, S. Seshan, T. Tuschl, M. Suthanthiran, T. Muthukumar
Weill Cornell Medicine, New York, NY
*Purpose: Test the hypothesis that single cell RNA transcriptomics will further the precision transplantation medicine approaches and address important conundrums in clinical transplantation.*Methods: We studied…
2020 American Transplant Congress
Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, I. Yakubu¹, S. Paluri¹, A. Chachar¹, J. Chang², I. Moinuddin¹, L. Kamal¹, M. Levy¹, C. Bhati¹, A. King¹, P. Kimball¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²ATAGC, Edmonton, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. Basic and…
2020 American Transplant Congress
Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: Update on the Take It Trial
E. Yoon¹, S. Hurr¹, L. Curtis¹, D. Ladner², S. Nair³, M. S. Wolf¹
¹Center for Applied Health Research on Aging (CAHRA), Northwestern University Feinberg School of Medicine, Chicago, IL, ²Surgery, Northwestern Medicine, Chicago, IL, ³Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ
*Purpose: In 2017, the TAKE IT trial began its evaluation of a multifaceted, technology-enabled, transplant center-based intervention to monitor medication adherence behaviors among Kidney Transplant…
2020 American Transplant Congress
Belatacept Every Two Month Maintenance Dosing in Kidney Transplantation: A Randomized, Non-Inferiority Trial
I. R. Badell, R. Parsons, S. Mead, S. Thomas, G. Karadkhele, S. Pastan, C. Larsen
Emory University School of Medicine, Atlanta, GA
*Purpose: Maintenance immunosuppression with belatacept following kidney transplantation results in a reduced risk of patient death and graft loss as compared to calcineurin inhibitors. However,…
2020 American Transplant Congress
Hydroxychloroquine is Associated with Better Patient and Graft Survival in Kidney Transplant Patients with Lupus Nephritis as Cause of ESRD
T. Singh¹, S. Garg², S. Panzer¹
¹Nephrology, University of Wisconsin, Madison, WI, ²Rheumatology, University of Wisconsin, Madison, WI
*Purpose: Hydroxychloroquine (HCQ) use leads to better patient and renal survival in patients with lupus nephritis (LN). Whether the clinical benefits of HCQ extends to…
2020 American Transplant Congress
Analyzing Causes for Death-Censored Graft Failure
M. Mayrdorfer, L. Liefeldt, N. Lachmann, W. Düttmann-Rehnolt, F. Halleck, M. G. Naik, P. Glander, K. Budde
Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Since it has been proposed that several causes could contribute to graft loss (GL), we analyzed graft failure in our center and attributed a…
2020 American Transplant Congress
Normothermic Ex-Vivo Kidney Perfusion is Superior to Anoxic and Oxygenated Hypothermic Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts
L. Mazilescu¹, M. Kaths², P. Urbanellis¹, M. Hamar³, T. Goto¹, I. Linares-Cervantes¹, Y. Noguchi¹, A. Konvalinka¹, A. Ghanekar¹, D. Bagli⁴, R. John⁵, L. Robinson⁶, M. Selzner¹
¹Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada, ²Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany, ³Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ⁴Departments of Surgery(Urology)&Physiology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Laboratory Medicine & Pathobiology, Toronto General Hospital, Toronto, ON, Canada, ⁶Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: To increase the donor pool, better preservation strategies for the storage of marginal kidney grafts are crucial. Currently, kidney grafts are either stored on…
2020 American Transplant Congress
Creation of a Low-Cost Kidney Transplant Surgery Simulator and Survey of its Utility for Education
V. Melkonian, T. Huy, C. Varma, M. Nazzal, H. Randall, M. Nguyen
Department of Surgery, Saint Louis University, Saint Louis, MO
*Purpose: Surgical skills education in transplant surgery is challenging as center-specific outcomes are scrutinized and trainees’ exposure to the sub-specialty is decreasing. Simulation could overcome…