2020 American Transplant Congress
Two Pilot Studies Exploring the Diagnostic and Predictive Potential of Serum LAG3 and FGL1 in Kidney Transplant Recipients
*Purpose: Lymphocyte activation gene 3 (LAG3), an immune checkpoint, plays an important role in the negative regulation of immune response and the induction of immune…2020 American Transplant Congress
Tyrosine Receptor Kinase Axl Regulates Intragraft Trafficking of Alloreactive T Cells Post Kidney Transplantation
1Nephrology/Medicine, Duke University, Durham, NC, 2Pathology, Northwestern University, Chicago, IL
*Purpose: Previous studies have shown that receptor tyrosine kinase Axl, primarily expressed on dendritic cells and some tissue-specific macrophage population, is required for T cells…2020 American Transplant Congress
To Wait or Not to Wait: The Survival Benefit of Preemptive Kidney Transplantation after Accounting for Lead Time Bias
1Johns Hopkins, Baltimore, MD, 2SRTR, Minneapolis, MN
*Purpose: Over 2,000 preemptive living donor kidney transplants (LDKT) per year are performed in the US. Preemptive LDKT allows recipients to avoid dialysis, but increases…2020 American Transplant Congress
Racial Differences in Acceptance of Public Health Service (PHS) Increased Risk Kidneys and Hepatitis C (HCV) Nat Positive Kidneys
Tulane University, New Orleans, LA
*Purpose: PHS increased risk kidneys and HCV NAT positive kidneys represent a significant proportion of the donor pool however, acceptance demands explicit patient consent that…2020 American Transplant Congress
An Optimized Integrative Model Using Urinary Chemokines for Noninvasive Diagnosis of Acute Allograft Rejection
*Purpose: The aim of this study was to optimize the performance of urinary chemokines C-X-C motif ligand (CXCL) 9 and CXCL10 as noninvasive diagnostic markers…2020 American Transplant Congress
HLA Cw12 in Kidney Transplant Recipients is a Novel Risk Factor for the Development of Post-Transplantation Diabetes: A Single-Centre Retrospective Study
*Purpose: Counselling kidney transplant candidates for their personalised risk of developing post-transplantation diabetes mellitus (PTDM) requires an understanding of risk factors. While some risk factors…2020 American Transplant Congress
Assessing Interventions to Improve Patient Care Conducted by Pharmacists at an Outpatient Renal Transplant Clinic within a Collaborative Pharmacy Practice Agreement
Vanderbilt University Medical Center, Nashville, TN
*Purpose: A collaborative pharmacy practice agreement (CPPA) permits pharmacists to perform clinical services under the guidance of a supervising physician without direct physician intervention. We…2020 American Transplant Congress
Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity after Switch to Belatacept-Based Regimen after Kidney Transplantation
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.*Methods: 19 patients with evidence of calcineurin inhibitor (CNI) toxicity…2020 American Transplant Congress
Improvement in Long Term Kidney Transplant Survival Most Dramatic among Minorities, Diabetics and Older Patients
*Purpose: Short-term and long-term kidney transplant graft survival has been improving over time, but whether this improvement in outcomes is more pronounced in the early…2020 American Transplant Congress
Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury
*Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…
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