2020 American Transplant Congress
Immune Checkpoint Inhibitor Use in Kidney Transplant Recipients: Rejection Risk, Prevention and Transcriptional Signature in Allograft
1Brigham and Women's Hospital, Boston, MA, 2University of Alberta, Edmonton, AB, Canada
*Purpose: Immune checkpoint inhibitor (ICI) use has changed the landscape of cancer treatment. Several cases of acute rejection in use of ICI have been reported,…2020 American Transplant Congress
Health Mindsets Can Influence Psychosocial Ratings in Pediatric Renal Transplant Patients
Surgery, Stanford University, Stanford, CA
*Purpose: There is a large body of research which shows psychological states can influence health and behavioral outcomes, yet in clinical practice, psychosocial states are…2020 American Transplant Congress
Single Cell RNA Sequencing of Murine Kidney Allografts Identifies Macrophage Gene Signature Associated with Acute Rejection
*Purpose: Evaluating kidney allografts using single cell RNA sequencing (scRNAseq) can provide a comprehensive qualitative and quantitative gene expression data on thousands of individual cells.…2020 American Transplant Congress
Long-Term Outcomes of Single Kidney Transplants from Small Pediatric Donors
Weill Cornell Medical College, New York, NY
*Purpose: On September 5th, 2019, UNOS implemented an important policy change in the allocation of kidneys from small pediatric donors. In trying to balance achieving…2020 American Transplant Congress
1 -Year Protocol Biopsies in Pediatric Kidney Transplant Children: Are Unfavorable Histological Lesions Related to No Adherence?
*Purpose: In adults with kidney transplantation (KT), histological findings in surveillance biopsies at 1-year post KT are independent correlate to short and long-term graft survival.…2020 American Transplant Congress
Delayed Introduction of Mammalian Inhibitors of Rapamycin (mTOR) Post Kidney Transplantation Might Avoid the Chronic Nephrotoxicity of Calcineurin Inhibitors. Herein We Are Reporting an Eight-Years Single Center Experience of mTOR-Based Immunosuppression Regimen in Comparison with Cyclosporin-Based Regimen
*Purpose: Delayed introduction of mTOR inhibitors post kidney transplantation might avoid the chronic nephrotoxicity of CNI: eight-years single center experience.*Methods: This is a retrospective analysis…2020 American Transplant Congress
Potential Cost-Savings Associated with ANG-3777 for the Treatment of Delayed Graft Function in Kidney Transplantation
*Purpose: We created a medical cost offset model based upon the results of a Phase 2, double-blind, randomized controlled trial of ANG-3777, a hepatocyte growth…2020 American Transplant Congress
Kidney Transplantation and Short Bowel Syndrome: Outcomes and Challenges
*Purpose: Among patients with short bowel syndrome (SBS), kidney disease is highly prevalent due to volume depletion, crystal nephropathies, and many other reasons. Kidney transplantation…2020 American Transplant Congress
Comparison of Anti-Thymocyte Globulin and Alemtuzumab as Induction Therapy in Older Kidney Transplant Recipients
Rush University Medical Center, Chicago, IL
*Purpose: The purpose of this study is to evaluate the safety and efficacy of induction with either anti-thymocyte globulin (ATG) (total dose 5 mg/kg) or…2020 American Transplant Congress
The Impact of Pre-Existing and New Onset Diabetes on Healthcare Utilization Following Kidney Transplantation
*Purpose: Diabetes (DM) represents a global epidemic; it is the leading cause of ESRD in the US and a predominant etiology for kidney transplantation (KTX).…
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