Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Male Native Hawaiians and Pacific Islanders are at Risk for Delayed Graft Function after Renal Transplantation
L. Lee¹, K. Bozhilov², L. L. Wong²
¹The Queen's Transplant Center, Honolulu, HI, ²Surgery, University of Hawaii - John A. Burns School of Medicine, Honolulu, HI
*Purpose: Native Hawaiians and Pacific Islanders (NHPI) have an increased risk of chronic kidney disease with disproportionately fewer patients receiving kidney transplants; this study aims…
2020 American Transplant Congress
Membrane Expression of CD163 and CD206 by Blood Monocytes is Upregulated in Kidney Allograft Recipients
I. Striz, L. Curnova, V. Svachova, M. Fialova, M. Novotny, O. Viklicky
Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Blood monocytes differentiating into tissue macrophages or dendritic cells are involved in multiple immune responses including reactions to the transplanted allograft. Peripheral monocytes can…
2020 American Transplant Congress
Impact of Extracorporeal Photopheresis in a Full-Mismatch Kidney Transplant Rat Model
J. Rovira¹, G. J. Piñeiro², M. Lazo-Rodriguez³, M. J. Ramirez-Bajo¹, E. Banon-Maneus³, N. Hierro-Garcia³, P. Ventura-Aguiar², J. Cid⁴, M. Lozano⁴, F. Diekmann²
¹Laboratori Experimental de Nefrologia i Trasplantament (LENIT), IDIBAPS, Barcelona, Spain, ²Department of Nephrology and Renal Transplantation, Hospital Clínic de Barcelona, Barcelona, Spain, ³Laboratori Experimental de Nefrologia i Trasplantament (LENIT), Fundació Clínic per la Recerca Biomèdica (FCRB), Barcelona, Spain, ⁴Apheresis Unit, Department of Hemotherapy and Hemostasis, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: Extracorporeal photopheresis (ECP) is an immunomodulatory cell therapy based on the infusion of autologous cellular products exposed to ultraviolet light (UV), in the presence…
2020 American Transplant Congress
Effect of Low vs Standard Dosage of Anti-Thymocyte Globulin Induction Therapy on the Co-Inducible Molecules (Cd28, CTLA-4, ICOS, PD-1) Expression Pattern in T Regulatory Cell
G. Queipo¹, A. Hernandez-Mendoza¹, M. Estrada-Matus², M. Fonseca-Sanchez¹, F. Oviedo¹, L. García-Cobarruvias³, J. Prieto Chávez⁴, L. Pizarro⁵, L. Morales-Buenrostro⁶
¹Human Genetics, Hospital General de Mexico-Eduardo Liceaga Facultad de Medicina UNAM, Mexico City, Mexico, ²Nephrology, Instituno Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ³Transplant Unit, Hospital General de Mexico-Eduardo Liceaga, Mexico City, Mexico, ⁴Flow Cytometry Core, Mexican Social Security Institute, Mexico City, Mexico, ⁵Unit on Immunochemistry, Medical Research, Specialties Hospital of the National Medical Centre “SigloXXI”, Mexico City, Mexico, ⁶Nephrology, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City, Mexico
*Purpose: Two thymoglobulin (TG) dosages effect on the Tregulatory cell (Treg) and describe the behavior of the co-stimulatory pathways in terms of FIM and gene…
2020 American Transplant Congress
Improving DRG Based Reimbursement to Reflect Complexity of Kidney Transplant
I. R. Schwantes¹, M. Schnitzler², K. Lentine², A. Reed¹, D. A. Axelrod³
¹Surgery, University of Iowa, Iowa City, IA, ²Saint Louis University, St. Louis, MO, ³Surgery, Universtiy of Iowa, Iowa City, IA
*Purpose: More than 90,000 individuals await a kidney transplant (KTx) in the US, yet up to 20% of recovered kidneys are discarded. Organ Transplant Centers…
2020 American Transplant Congress
Development of a New Kidney Paired Donation (KPD) Program: Starting a Domino Chain with a Deceased Donor
L. Furian¹, C. Di Bella², C. Silvestre², F. Neri², F. Tuci², M. Cardillo³, E. Cozzi⁴, P. Rigotti¹
¹Kidney and Pancreas Transplantation Unit, University of Padova, Padua, Italy, ²Kidney and Pancreas Transplantation Unit, University of Padova, Italy, Italy, ³Italian National Transplant Center, Rome, Rome, Italy, ⁴Transplant Immunology Unit, Padova University-Hospital, Padua, Padua, Italy
*Purpose: The option of initiating a domino chain of living donor kidney transplants with a deceased donor (DD) has been proposed but never enforced. The…
2020 American Transplant Congress
Three Year Post Co-Stimulation Blocking Agent (Belatacept) Switch Outcomes of Kidney Transplant Patients Diagnosed with Post-Transplant Thrombotic Microangiopathy
A. Gamilla-Crudo, S. Hussain, A. Rizvi, R. Ramirez, M. Kueht, H. Stevenson-Lerner, J. Fair, M. Mujtaba
UTMB, Galveston, TX
*Purpose: Thrombotic microangiopathy (TMA) can happen after kidney transplant. It may occur de novo or as a recurrent disease. De novo is usually associated with…
2020 American Transplant Congress
The Clinical Significance of C1q+ Antibodies in Pediatric Kidney Transplant Recipients
N. Hayde¹, S. Solomon², A. Colovai¹
¹Montefiore Medical Center, Bronx, NY, ²Westchester Medical Center, Valhalla, NY
*Purpose: To evaluate the impact of denovo DSA (C1q+ vs C1q-) on graft outcomes in pediatric kidney transplant recipients.*Methods: Children transplanted between 2009 and 2016…
2020 American Transplant Congress
Uromodulin to Osteopontin Ratio in Deceased Donor Urine is Associated with Kidney Graft Outcomes
S. G. Mansour¹, C. Liu², Y. Jia², P. Reese³, I. Hall⁴, T. El-Achkar⁵, K. LaFavers⁵, W. Obeid², M. Thangamani⁶, A. Rosenberg², M. Doshi⁷, E. Akalin⁸, J. Bromberg⁹, M. Harhay¹⁰, S. Mohan¹¹, B. Schröppel¹², P. Daneshpajouhnejad², P. Singh¹³, F. Weng¹⁴, H. Thiessen-Philbrook², C. Parikh²
¹Yale, New Haven, CT, ²Johns Hopkins, Baltimore, MD, ³UPenn, Philadelphia, PA, ⁴Univ of Utah, Salt Lake City, UT, ⁵Indiana Univ, Bloomington, IN, ⁶Cornell, New York, NY, ⁷Univ of Michigan, Ann Arbor, MI, ⁸Montefiore, Bronx, NY, ⁹Univ of Maryland, College Park, MD, ¹⁰Drexel, Philadelphia, PA, ¹¹Columbia, NY, NY, ¹²Univ Hosp, Ulm, Germany, ¹³Thomas Jefferson, Philadelphia, PA, ¹⁴St. Barnabas, Livingston, NJ
*Purpose: Deceased-donor kidneys often experience extensive injury, activating adaptive and maladaptive pathways. While these adaptive and maladaptive mechanisms are initiated in donor kidneys prior to…
2020 American Transplant Congress
Your Path to Transplant Tailored Education Increases Living Donation Transplant Actions and Wait-Listing Rates: Final Randomized Controlled Trial Findings
A. Waterman¹, Y. Cui², J. L. Beaumont², J. D. Peipert³, A. Paiva⁴, M. L. Robbins⁴
¹Transplant Research and Education Center, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³Feinberg School of Medicine, Northwestern University, Chicago, IL, ⁴Department of Psychology, University of Rhode Island, Kingston, RI
*Purpose: Tailoring education and behavior change interventions to address gaps in individual patients’ knowledge, readiness, and socio-economic challenges may help more end-stage kidney disease patients…