2020 American Transplant Congress
Improvement in Long Term Kidney Transplant Survival Most Dramatic among Minorities, Diabetics and Older Patients
*Purpose: Short-term and long-term kidney transplant graft survival has been improving over time, but whether this improvement in outcomes is more pronounced in the early…2020 American Transplant Congress
Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury
*Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…2020 American Transplant Congress
Temporal Trends in Utilization and Outcomes of Sclerotic Donor Kidneys in the United States
Johns Hopkins University, Baltimore, MD
*Purpose: Sclerotic donor kidneys (SDK, glomerulosclerosis ≥20% on biopsy) represent a possible expansion to the donor pool but are often discarded due to historical association…2020 American Transplant Congress
Conversion to Sirolimus to Prevent Recurrent Cytomegalovirus Infection/Disease: A Prospective and Randomized Trial
Hospital do Rim - UNIFESP, São Paulo, Brazil
*Purpose: Recurrent cytomegalovirus (CMV) infection occurs in 30-35% of kidney transplant recipients after completion of treatment and/or preemptive therapy. There is no consensus on the…2020 American Transplant Congress
Belatacept Provides Superior Inhibition of Donor Specific Antibody Formation in Kidney Transplant Recipients with Acute Rejection
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA
*Purpose: The factors responsible for chronic renal allograft dysfunction and premature graft loss are incompletely understood and likely multifactorial. Immunologic injury partially attributable to the…2020 American Transplant Congress
The Role of the Molecular Microscope to Guide Therapy for T-Cell Mediated Rejection in Kidney Transplants
1Virginia Commonwealth University, Glen Allen, VA, 2ATAGC, Edmonton, AB, Canada
*Purpose: Histologic lesions (I+T) to characterize T-cell mediated rejection (TCMR) can be non-specific. In some cases the inflammation may represent a ‘response to wounding’ rather…2020 American Transplant Congress
Anti-HLA IgM Antibodies are Unaffected by Imlifidase (IdeS) Treatment
*Purpose: The immunoglobulin G (IgG)-degrading cysteine protease, imlifidase (IdeS) is an IgG endopeptidase under development as a rapid desensitization treatment in kidney transplantation. Imlifidase is…2020 American Transplant Congress
Clinicopathological Evaluation of Long-Term Survivor More Than 10 Years after Living Kidney Transplant with Corticosteroid Early Withdrawal Protocol
*Purpose: We have previously reported that favorable short-term outcomes of kidney recipients were achieved by corticosteroid early withdrawal protocol (CSEW) compared to the conventional protocol…2020 American Transplant Congress
Paired-Donor Kidney Exchange Has Comparable Early Graft Function to Directed Living Donor
Transplant Surgery, University of Virginia, Charlottesville, VA
*Purpose: Living kidney donation in the United States is associated with improved graft and patient survival. However, there is minimal data on graft function in…2020 American Transplant Congress
Hepatitis C-Infected Donors and Hepatitis C-Infected Recipients: Analysis of Renal Transplant Outcomes
*Purpose: Increased utilization of hepatitis C virus infected organs could reduce the supply demand mismatch in organ transplantation. At this time, there is little data…
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