Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Mycophenolic Acid Exposure in Young, Middle Age and Older Stable Renal Transplant Recipients
K. Tornatore¹, K. Attwood², R. Venuto³
¹School of Pharmacy; University at Buffalo, Williamsville Buffalo, NY, ²School of Pharmacy; University at Buffalo Department of Biostatistics; Roswell Park Comprehensive Cancer Center, Buffalo, NY, ³School of Medicine; University at Buffalo, Buffalo, NY
*Purpose: Mycophenolic acid (MPA) is an essential drug in maintenance immunosuppressive regimens. In spite of increased kidney transplants in the elderly, limited pharmacokinetic investigations comparing…
2020 American Transplant Congress
The Clinical Usefulness of Preformed C1q-Binding Donor-Specific Antibodies in Kidney Transplantation
S. Lee, E. Ko, B. Chung, C. Yang
Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: The anti-human leukocyte antigen (HLA) antibodies are well known for risk factor of rejection or allograft loss. Additionally, de novo complement component 1q-binding donor-specific…
2020 American Transplant Congress
Are Living Donor Offers a Missed Opportunity? A Social Network Analysis of End-Stage Renal Disease Patients
A. Gillespie¹, J. Cappiello², R. L. Brown¹, H. M. Gardiner², E. L. Fink³, P. P. Reese⁴, C. Gadegbeku⁵, Z. Obradovic⁶
¹Lewis Katz School of Medicine at Temple University, Bala Cynwyd, PA, ²Temple University College of Public Health, Philadelphia, PA, ³Lew Klein School of Media and Communication Temple University, Philadelphia, PA, ⁴Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, ⁵Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁶Center for Data Analytics and Biomedical Informatics at Temple University, Philadelphia, PA
*Purpose: Increasing the rates of living donor kidney transplantation is a priority, yet not much is known about the members of an end-stage renal disease…
2020 American Transplant Congress
Surgical Nephrectomy of the Native Kidneys: Greater Cardiovascular Benefit in Renal Transplant Recipients?
J. Sleiman, G. Soler Pujol, L. Brukman, G. Laham, M. Schiavone, C. Castellaro, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: The survival of the graft in patients (px) with renal transplantation (RT) depends on multiple cardiovascular (CV) factors. With CKD progression, sympathetic activity increases,…
2020 American Transplant Congress
To Donate or Not to Donate? The Balancing Act of Apol-1 Genetic Testing in Potential Living Kidney Donors of African Descent in Resource Limited Countries
O. Ekwenna¹, C. Okwuonu², I. Thoms³
¹University of Toledo College of Medicine, Toledo, OH, ²Nephrology and Medicine, Federal Medical Center Umuahia, Umuahia, Nigeria, ³Nephrology and Medicine, Mt. St John Medical Center, St. John, Antigua and Barbuda
*Purpose: To report our findings of APOL-1 testing in individuasl of African descent presenting as potential living kidney donors in resource limited countries; Antigua and…
2020 American Transplant Congress
Cryptococcosis In Kidney Transplant Recipients: A Multicenter Retrospective Case-Control Study
L. Tardieu¹, O. Lortholary², F. Lanternier², A. Scemla³, C. Rafat¹
¹Urgences Néphrologiques et Transplantation Rénale, Hôpital Tenon, APHP, Paris, France, ²Service de Maladies Infectieuses et Tropicales – Centre d’Infectiologie Necker-Pasteur, Hôpital Necker, APHP, Paris, France, ³Service de Transplantation Rénale, Hôpital Necker, APHP, Paris, France
*Purpose: Cryptococcosis is the third most common invasive fungal infection in organ transplant recipients.The clinical approach and prognosis has been previously investigated in the setting…
2020 American Transplant Congress
Deceased Donor Families and Authorization for Research: Differences among Ethnic Groups
M. Ortigosa-Goggins, J. J. Gaynor, E. Shipman, L. Preczewski, G. Guerra
Miami Transplant Institute, University of Miami, Miami, FL
*Purpose: Clinical research in transplantation is key to advancement of the field. NIH-sponsored trials such as HOPE in Action and APOLLO network require deceased donor…
2020 American Transplant Congress
Pancreatic Cysts Identified During Evaluation for Kidney Transplant: Selective Application of Endoscopic Ultrasound
S. Merani, E. Edney, S. Singh, S. Westphal, L. Vargas
University of Nebraska Medical Center, Omaha, NE
*Purpose: Transplant recipients have a higher incidence of risk-adjusted malignancy than the general population, likely due to immunosuppression. The evaluation of a potential transplant candidate…
2020 American Transplant Congress
Serum CXCL13 Levels Indicate Humoral Alloreactivity and Donor Specific Antibody Formation
E. S. Crichton, S. Zeng, I. Badell
Emory University, Atlanta, GA
*Purpose: Donor-specific antibodies (DSA) are an increasingly recognized cause of allograft injury, yet biomarkers to predict their development or guide their clinical management post-transplant are…
2020 American Transplant Congress
Routine Human Renal Allograft Biopsies Analyzed for mRNA Content with a Novel Nanostring mRNA Human Organ Transplant (HOT) Panel
I. Rosales¹, R. Smith¹, E. Acheampong¹, T. Kawai¹, T. Tsuji², K. Hotta³, R. Colvin¹
¹Massachusetts General Hospital, Boston, MA, ²Sapporo City General Hospital, Sapporo, Japan, ³Hokkaido University Hospital, Sapporo, Japan
*Purpose: In 2019 a Banff Working Group and Nanostring Technologies developed a panel of 770 mRNA probes for assessment of human organ allografts, based on…