ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2020 American Transplant Congress

    Longitudinal Study Investigating Characteristics of Human Polyimaviruses Infection after Kidney Transplantation

    E. Favi1, S. Delbue2, C. Colico1, L. Signorini2, L. Clementoni1, M. Ferraresso1

    1Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, 2Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy

    *Purpose: Human Polyomaviruses (HPyV) infections are extremely common, ranging from 60% to 100% in the general population, depending on the virus. After primary infection, which…
  • 2020 American Transplant Congress

    Anticipated Observations: The Role of DQ Antigen Frequencies among Donors and Recipients in a Pediatric Renal Transplant Cohort

    S. Gattis1, R. George2, R. Liverman3, A. Serluco3, R. Garro2, J. Figueroa2, R. A. Bray2, H. M. Gebel2, H. C. Sullivan2

    1Emory Healthcare, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA

    *Purpose: Donor specific HLA antibodies (DSA) that develop in the face of donor-recipient HLA mismatches are well-established independent predictors of graft loss in solid organ…
  • 2020 American Transplant Congress

    Complement Activation and Delayed Graft Function after Kidney Transplantation

    C. Arias-Cabrales1, M. Pérez-Sáez1, M. Riera1, J. Gimeno2, D. Benito1, D. Redondo-Pachón1, A. Buxeda1, C. Burballa1, M. Crespo1, J. Pascual1, E. Rodríguez1

    1Nephrology, Hospital Del Mar, Barcelona, Spain, 2Pathology, Hospital Del Mar, Barcelona, Spain

    *Purpose: Ischemia-reperfusion (I/R) damage is the most important cause of delayed graft function (DGF), which has a negative impact on kidney transplant (KT) outcomes. Complement…
  • 2020 American Transplant Congress

    A Technique for Ex-Vivo Perfusion of Donor Kidneys for Transplantation in the Mouse

    R. Plenter1, S. Jain2, J. J. Pomposelli1, T. Nydam1, A. Jani2

    1Pulmonary Division, University of Colorado, Aurora, CO, 2Renal Division, University of Colorado, Aurora, CO

    *Purpose: Ex-vivo perfusion of donor kidneys is widely employed in the US and significantly reduces DGF. Development of a pre-clinical perfusion technique may provide an…
  • 2020 American Transplant Congress

    Comparison of 1-Year Incidence of De Novo Donor Specific Antibodies between Thymoglobulin and Alemtuzumab Induction in Kidney Transplantation

    J. P. Knorr, C. Kallis, D. A. Portley, A. Jeyarajasingam, P. W. Lai, G. Bradauskaite, K. Khanmoradi

    Transplant Nephrology, Einstein Medical Center, Philadelphia, PA

    *Purpose: Development of de novo donor specific antibodies (dnDSA) after kidney transplantation (KTx) has been associated with acute and chronic antibody-mediated rejection, transplant glomerulopathy and…
  • 2020 American Transplant Congress

    Outcomes after Declining Offers from Older Donor Kidneys for Kidney Transplant Candidates

    J. D. Motter, L. Liyanage, K. R. Jackson, M. G. Bowring, T. Ishaque, Y. Yu, S. Yu, J. M. Garonzik-Wang, A. B. Massie, D. L. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Older donor kidneys (ODKs) are often declined as they are associated with higher post-transplant mortality and graft loss, yet those who decline may wait…
  • 2020 American Transplant Congress

    Anti-IL-6 Antibody Clazakizumab in Late Antibody-Mediated Rejection – Molecular Rebound Phenomena Under IL-6 Blockade?

    A. Borski1, S. Haindl2, M. Duerr3, K. Budde3, S. Schranz1, F. A. Eskandary2, K. Doberer2, P. F. Halloran4, E. Chong5, B. Jilma1, G. A. Böhmig2, M. Wahrmann2

    1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria, 2Department of Medicine III, Medical University of Vienna, Vienna, Austria, 3Charité Universitätsmedizin Berlin, Berlin, Germany, 4University of Alberta, Edmonton, AB, Canada, 5Vitaeris Inc., Vancouver, BC, Canada

    *Purpose: Late antibody-mediated rejection (ABMR) is well established as a major cause of kidney allograft failure. Targeting interleukin-6 (IL-6), a pro-inflammatory cytokine involved in B…
  • 2020 American Transplant Congress

    Multi- National Survey among Nephrologists & Transplant Surgeons about the Suitability and Acceptance of the Marginal Live Kidney Donors with Mild Hypertension

    Z. Arabi1, E. Elhassan1, A. Altheaby1, A. Hamad2, S. Kaysi3

    1KAMC, Riyadh, Saudi Arabia, 2The Regional Medical Center, Orangeburg, SC, 3CHR Orleans, Orleans, France

    *Purpose: There is variability among transplant centers in the acceptance of living donor candidates with well-controlled hypertension. Increased gestational hypertension and preeclampsia are more common…
  • 2020 American Transplant Congress

    New Everolimus Administration Targeting the Prevention of the Development of Antibody-Mediated Rejection Considering the Comparison of Growth and Survival in IgG and IgM Memory B Cells

    Y. Matsuda1, R. Imamura1, H. Tezuka2, S. Takahara1

    1Osaka University Graduate School of Medicine, Suita, Japan, 2Fujita Health University, Toyoake, Japan

    *Purpose: Some reports indicated that immunoglobulin (Ig) M antibodies corresponding to donor-specific antigen in addition to IgG antibodies are closely involved in the activation of…
  • 2020 American Transplant Congress

    Incidence and Outcomes of Secondary Cutaneous Malignancies among Renal Transplant Recipients

    T. Maw1, P. Vaidya1, J. Samaan2, S. Ghanshani1, G. In1

    1Keck School of Medicine, LA, CA, 2Cedar Sinai Hospital, LA, CA

    *Purpose: Solid-organ transplant recipients on immunosuppressive therapy are known to have higher morbidity and mortality from secondary malignancies; however, there are no established guidelines for…
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