Articles tagged "Kidney transplantation"

2020 American Transplant Congress
Retinal Vein Occlusion Incidence in Kidney Transplant Recipients in South Korea: A Long-Term Population-Based Study
J. Lee¹, S. Park¹, J. Kim¹, M. Yu², S. Baek³, K. Han⁴, D. Kim¹, K. Joo¹, Y. Kim¹, H. Lee¹, Y. Kim¹
¹Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea, Republic of, ³Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea, Republic of, ⁴Medical Statistics, College of Medicine, Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: The risk of retinal vein occlusion(RVO) is known to increase in patients with chronic kidney disease, especially end-stage renal disease (ESRD). However, little is…
2020 American Transplant Congress
Kidney Transplantation from HBsAg+ Living Donors to HBsAg- Recipients: A Propensity Score-Matched Study at a High-Volume Center in China
X. Wang, J. Liu, T. Song, Y. Fan, Z. Huang, T. Lin
Urology, West China Hospital, Chengdu, China
*Purpose: Data on kidney transplantation (KTx) from hepatitis B surface antigen (HBsAg)+ donors to HBsAg- recipients [D(HBsAg+)/R(HBsAg-)] are limited. We aimed to report the outcomes…
2020 American Transplant Congress
Efficacy and Safety of Cytomegalovirus Antiviral Preventive Strategies in Kidney Transplant: A Systematic Literature Review
A. Raval¹, K. Kistler², Y. Tang¹, Y. Murata¹, D. Snydman³
¹Merck & Co., Inc., Kenilworth, NJ, ²Evidera, Inc., Waltham, MA, ³Tufts Medical Center, Boston, MA
*Purpose: Cytomegalovirus (CMV) is associated with significant mortality and morbidity in kidney transplant recipients (KTRs). Various CMV anti-viral (AV) preventive strategies have been utilized in…
2020 American Transplant Congress
Analysis of Pre-Transplant Resuscitation Factors Influencing Immediate Graft Function after Deceased Donor Kidney Transplantation
S. Park
General Surgery, Seoul St. Mary's Hospital, Seoul, Korea, Republic of
*Purpose: The management of a deceased donor in the intensive care unit before organ transplantation is important for the outcome of the recipient. Herein, we…
2020 American Transplant Congress
Native Nephrectomy at the Time of Transplant: Risk for Adrenal Injury?
T. Salinas¹, D. Dadhania¹, J. Lee¹, M. Aull¹, S. Kapur², M. Lubetzky¹
¹Nephrology, NY Presbyterian- Weill Cornell, New York, NY, ²Surgery, NY Presbyterian- Weill Cornell, New York, NY
*Purpose: Living donor studies have demonstrated that native nephrectomy (Nx) is associated with transient but symptomatic loss of adrenal function. Although surgical complications from simultaneous…
2020 American Transplant Congress
Microarray and RNA-Seq Analysis of Rejection in Formalin-Fixed Paraffin-Embedded (FFPE) Biopsies: Comparing FFPE to Conventionally Stabilized (RNAlater Solution) Biopsies
P. Halloran¹, K. Famulski¹, J. Reeve¹, J. Huang², N. Alexandrov²
¹University of Alberta, Edmonton, AB, Canada, ²R&D Transplant Diagnostics Division, Thermo Fisher Scientific, Los Angeles, CA
*Purpose: Molecular understanding of organ transplant biopsies requires genome-wide measurements and molecular classifiers. To assess potential of performing molecular diagnostics on formalin-fixed paraffin-embedded (FFPE) biopsies,…
2020 American Transplant Congress
Establishing an Induction Protocol for Long-Term Multilineage Mixed Chimerism in Rhesus Macaques
K. Bruestle¹, H. Sakai¹, F. Fredriksson¹, B. Piegari¹, D. Ekanayake-Alper¹, A. McLuckie², R. Ober², J. Weiner¹, A. Iuga³, S. M. Coley³, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Institute for Comparative Medicine, Columbia University, New York City, NY, ³Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Mixed chimerism (MC) induction via non-myeloablative conditioning and bone marrow transplantation (BMT) induces tolerance to solid organs. Our standard MC induction protocol in cynomologous…
2020 American Transplant Congress
Geographic Variation in Listing for Kidney Transplantation: A State-Level Assessment of Access among Patients with End-Stage Renal Disease in the United States
M. N. Mustian, H. Qu, D. Anderson, P. A. MacLennan, R. D. Reed, C. Kale, B. Orandi, B. A. Shelton, V. Kumar, M. Hanaway, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Barriers to deceased donor kidney transplantation (DDKT) exist, including referral for transplant and waitlist addition, which may vary regionally. The objective of this study…
2020 American Transplant Congress
Determinants of Cardiovascular Benefit Observed in a Population with a Functioning Renal Transplant versus Patients Undergoing Chronic Dialysis
J. Sleiman, C. Castellaro, G. Laham, M. Schiavone, M. Biain, L. Brukman, G. Soler Pujol, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: Patients (pts) with end stage renal disease have a high morbidity and mortality rate, mostly due to cardiovascular events (CV). Transplantation (Tx) improves survival…
2020 American Transplant Congress
Early Impact of Interleukin-6 Blockade on the Distribution of Peripheral Blood Immune Cell Subpopulations – 3-Month Results of a Phase 2 Trial Evaluating Clazakizumab in Late Antibody-Mediated Rejection
K. A. Doberer¹, G. A. Boehmig¹, M. Streitz², S. Schlickeiser², F. Bauernfeind¹, A. Spittler³, B. Jilma⁴, F. Eskandary¹, E. Chong⁵, S. Schranz⁴, K. Budde⁶, M. Dürr⁶
¹Department of Medicine III, Medical University of Vienna, Vienna, Austria, ²Charité Universitätsmedizin Berlin, Institute of Medical Immunology, Berlin, Germany, ³Center of Translational Research, Medical University of Vienna, Vienna, Austria, ⁴Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria, ⁵Vitaeris Inc., Vancouver, BC, Canada, ⁶Division of Nephrology and Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Interleukin-6 (IL-6) is considered to play a critical role within the multifacted pathophysiological process of antibody-mediated rejection (ABMR), including modulation of regulatory T cells…