Articles tagged "Kidney transplantation"

2020 American Transplant Congress
HCV Viremic Kidneys for Uninfected Recipients with DAA Treatment Offers Sustained Virologic Response
J. Torabi, A. Montal, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, E. Akalin, J. Melvin, M. Kinkhabwala, S. Greenstein, J. P. Rocca, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: Development of direct acting anti-viral medications (DAA) have offered cure rates for hepatitis C infection (HCV) approaching 100%. This has provided the ability to…
2020 American Transplant Congress
Impact of Pregnancy on Kidney Transplant Recipients: A Propensity Score-Matched Study
T. Abe, A. Taniguchi, M. Kawamura, S. Nakazawa, T. Kato, R. Imamura, N. Nonomura
Department of Urology, Osaka University Graduate School of Medicine, Suita, Japan
*Purpose: This study aimed to evaluate whether the experience of pregnancy and delivery would be associated with poor maternal outcome among kidney transplant recipients.*Methods: A…
2020 American Transplant Congress
Assessment of Time to Therapeutic Tacrolimus Levels Following Renal Transplantation in a Non-Weight-Based Dosing Model
J. Banbury¹, A. Dodson¹, C. Lin², K. Gutierrez¹
¹University of Alabama at Birmingham Hospital, Birmingham, AL, ²Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL
*Purpose: The optimal initial dose for tacrolimus (TAC) after renal transplant (RT) remains controversial with limited evidence comparing weight-based and conservative strategies. Recent literature suggests…
2020 American Transplant Congress
Does Transplantation of Hepatitis C Infected Kidneys Into Uninfected Recipients Cause Hepatitis C-Associated Kidney Injury?
R. H. Naik, S. Shawar, R. C. Forbes, H. Schaefer, D. Shaffer, M. Rossi, V. Imperio, B. P. Concepcion, M. Kapp
Vanderbilt University Medical Center, Nashville, TN
*Purpose: With increasing utilization of Hepatitis C infected (HCV+) kidneys for transplantation into uninfected (HCV-) recipients, there is concern for the development of HCV-associated kidney…
2020 American Transplant Congress
The Effect of B Cell Depletion Therapies on Preformed Xenoantibodies in Transplant Recipient
S. Yeh¹, N. A. Wilson², A. Djamali², R. Redfield³
¹Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, ²Medicine/Nephrology, University of Wisconsin-Madison, Madison, WI, ³Surgery, University of Wisconsin-Madison, Madison, WI
*Purpose: To assess the effect of B cell depletion therapies on preformed xenoantibodies in transplant recipient. Preformed xenoantibodies are a significant barrier to successful xenotransplantation.…
2020 American Transplant Congress
Combined Phenotyping to Identify Kidney Transplants at Greatest Risk after Subclinical Acute Rejection
S. Park¹, R. Heilman², E. Poggio³, D. Taber⁴, L. Zhao¹, K. Guo¹, S. Kurian⁵, C. Rebello¹, S. Brietigam¹, M. Abecassis⁶, J. Friedewald¹
¹Northwestern University, Chicago, IL, ²Mayo Clinic, Scottsdale, AZ, ³Cleveland Clinic, Cleveland, OH, ⁴MUSC, Charleston, SC, ⁵Scripps, La Jolla, CA, ⁶University of Arizona, Tucson, AZ
*Purpose: We hypothesize that the combination of protocol biopsy histology and gene expression profiles (GEP) for subclinical acute rejection (subAR) in the blood will improve…
2020 American Transplant Congress
The Role of Galectin-1 and Basement Membrane Remodeling in Kidney Antibody-Mediated Rejection
S. Clotet-Freixas¹, C. McEvoy¹, I. Batruch², M. Kotlyar³, C. Pastrello³, J. Van¹, M. Arambewela¹, A. Boshart¹, S. Farkona¹, A. Bozovic⁴, V. Kulasingam⁴, P. Chen¹, I. Jurisica³, A. Chruscinski¹, R. John⁴, A. Konvalinka⁵
¹Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ²Department of Laboratory Medicine and Pathobiology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada, ³Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁴Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁵Department of Medicine, Division of Nephrology, University Health Network, Toronto, ON, Canada
*Purpose: Antibody-mediated rejection (AMR), the leading cause of kidney graft loss, is caused by anti-HLA and non-HLA antibodies against proteins in two main kidney compartments:…
2020 American Transplant Congress
Long Term Outcomes of Hypertensive Kidney Donors
H. Ibrahim, S. Hebert, H. E. Adrogue, D. T. Nguyen, E. A. Graviss, A. Gaber, A. Matas
Houston Methodist Hospital, Houston, TX
*Purpose: Many people with hypertension are excluded from kidney donation fearing that hypertension is a major cause of CKD and its impact maybe magnified after…
2020 American Transplant Congress
Impact of Severity of Glomerulosclerosis on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury
A. Brar¹, A. Gruessner², D. Adey¹, M. Salifu²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: With long waitlist times for renal transplantation,there is a need to reduce discard rates of donor kidneys.The purpose of this study is to assess…
2020 American Transplant Congress
Long-Term Outcomes for the Use of Native Small Capacity, Defunctionalized Bladders in Pediatric Kidney Transplantation
P. Vuong, A. Brubaker, L. Maestretti, W. Concepcion, A. Gallo
Stanford University Medical Center, Palo Alto, CA
*Purpose: Small capacity, defunctionalized urinary bladders present a challenge in pediatric kidney transplantation due to the inability to perform an adequate anti-reflux ureterocystostomy in a…