ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2020 American Transplant Congress

    Assessing Interventions to Improve Patient Care Conducted by Pharmacists at an Outpatient Renal Transplant Clinic within a Collaborative Pharmacy Practice Agreement

    K. Johnson, R. Chelewski, A. Langone, M. Peter, A. Zuckerman

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: A collaborative pharmacy practice agreement (CPPA) permits pharmacists to perform clinical services under the guidance of a supervising physician without direct physician intervention. We…
  • 2020 American Transplant Congress

    Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity after Switch to Belatacept-Based Regimen after Kidney Transplantation

    J. Schaenman, M. Rossetti, H. Wilhalme, V. Groysberg, G. Sunga, J. Gadzhyan, B. Abdalla, E. Lum, P. Pham, G. Danovitch, J. Veale, H. A. Gritsch, D. Elashoff, E. Reed, S. Bunnapradist

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.*Methods: 19 patients with evidence of calcineurin inhibitor (CNI) toxicity…
  • 2020 American Transplant Congress

    Improvement in Long Term Kidney Transplant Survival Most Dramatic among Minorities, Diabetics and Older Patients

    E. D. Poggio1, S. Arrigain2, A. Wee3, D. C. Brennan4, J. D. Schold2

    1Nephrology, Cleveland Clinic, Cleveland, OH, 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, 3Urology, Cleveland Clinic, Cleveland, OH, 4Nephrology, Johns Hopkins, Baltimore, MD

    *Purpose: Short-term and long-term kidney transplant graft survival has been improving over time, but whether this improvement in outcomes is more pronounced in the early…
  • 2020 American Transplant Congress

    Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury

    L. Sheward1, J. Wedel1, N. Rodig1, R. Mannon2, O. Bestard3, V. Dharnidharka4, D. Zurakowski1, A. Kho1, T. Blydt-Hansen5, M. Seifert2, D. M. Briscoe1

    1Boston Children's Hospital, Boston, MA, 2University of Alabama at Birmingham, Birmingham, AL, 3Bellvitge University Hospital, Barcelona, Spain, 4St Louis Children's Hospital, St Louis, MO, 5BC Children's Hospital, Vancouver, BC, Canada

    *Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…
  • 2020 American Transplant Congress

    Temporal Trends in Utilization and Outcomes of Sclerotic Donor Kidneys in the United States

    J. D. Motter, K. R. Jackson, J. J. Long, A. B. Massie, N. M. Desai, D. L. Segev, J. M. Garonzik-Wang

    Johns Hopkins University, Baltimore, MD

    *Purpose: Sclerotic donor kidneys (SDK, glomerulosclerosis ≥20% on biopsy) represent a possible expansion to the donor pool but are often discarded due to historical association…
  • 2020 American Transplant Congress

    Conversion to Sirolimus to Prevent Recurrent Cytomegalovirus Infection/Disease: A Prospective and Randomized Trial

    L. Almeida Viana, M. Pontello Cristelli, G. Basso, D. Wagner Castro Lima Santos, M. Taver Costa Dantas, Y. Cardoso Dreige, L. Damasceno, M. Rika Nakamura, H. Tedesco-Silva, J. Medina-Pestana

    Hospital do Rim - UNIFESP, São Paulo, Brazil

    *Purpose: Recurrent cytomegalovirus (CMV) infection occurs in 30-35% of kidney transplant recipients after completion of treatment and/or preemptive therapy. There is no consensus on the…
  • 2020 American Transplant Congress

    Belatacept Provides Superior Inhibition of Donor Specific Antibody Formation in Kidney Transplant Recipients with Acute Rejection

    O. Cristea, C. Larsen, I. Badell

    Emory Transplant Center, Emory University School of Medicine, Atlanta, GA

    *Purpose: The factors responsible for chronic renal allograft dysfunction and premature graft loss are incompletely understood and likely multifactorial. Immunologic injury partially attributable to the…
  • 2020 American Transplant Congress

    The Role of the Molecular Microscope to Guide Therapy for T-Cell Mediated Rejection in Kidney Transplants

    D. Kumar1, M. Demehin1, J. Christensen1, L. Kamal1, I. Moinuddin1, M. Levy1, C. Bhati1, A. King1, H. D. Massey1, P. Halloran2, G. Gupta1

    1Virginia Commonwealth University, Glen Allen, VA, 2ATAGC, Edmonton, AB, Canada

    *Purpose: Histologic lesions (I+T) to characterize T-cell mediated rejection (TCMR) can be non-specific. In some cases the inflammation may represent a ‘response to wounding’ rather…
  • 2020 American Transplant Congress

    Anti-HLA IgM Antibodies are Unaffected by Imlifidase (IdeS) Treatment

    A. Runström1, R. Bockermann1, K. Sjöholm1, K. M. Roupé1, Å. Schiött1, L. Winstedt1, C. Kjellman1, T. Lorant2

    1Hansa Biopharma AB, Lund, Sweden, 2Section of Transplantation Surgery, Department of Surgical Sciences, Uppsala, Sweden

    *Purpose: The immunoglobulin G (IgG)-degrading cysteine protease, imlifidase (IdeS) is an IgG endopeptidase under development as a rapid desensitization treatment in kidney transplantation. Imlifidase is…
  • 2020 American Transplant Congress

    Clinicopathological Evaluation of Long-Term Survivor More Than 10 Years after Living Kidney Transplant with Corticosteroid Early Withdrawal Protocol

    H. Sasaki1, T. Tanabe1, H. Higuchi1, T. Tsujimoto2, H. Harada1

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, 2Pharmacy, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: We have previously reported that favorable short-term outcomes of kidney recipients were achieved by corticosteroid early withdrawal protocol (CSEW) compared to the conventional protocol…
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