2020 American Transplant Congress
An Optimized Integrative Model Using Urinary Chemokines for Noninvasive Diagnosis of Acute Allograft Rejection
*Purpose: The aim of this study was to optimize the performance of urinary chemokines C-X-C motif ligand (CXCL) 9 and CXCL10 as noninvasive diagnostic markers…2020 American Transplant Congress
HLA Cw12 in Kidney Transplant Recipients is a Novel Risk Factor for the Development of Post-Transplantation Diabetes: A Single-Centre Retrospective Study
*Purpose: Counselling kidney transplant candidates for their personalised risk of developing post-transplantation diabetes mellitus (PTDM) requires an understanding of risk factors. While some risk factors…2020 American Transplant Congress
Assessing Interventions to Improve Patient Care Conducted by Pharmacists at an Outpatient Renal Transplant Clinic within a Collaborative Pharmacy Practice Agreement
Vanderbilt University Medical Center, Nashville, TN
*Purpose: A collaborative pharmacy practice agreement (CPPA) permits pharmacists to perform clinical services under the guidance of a supervising physician without direct physician intervention. We…2020 American Transplant Congress
Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity after Switch to Belatacept-Based Regimen after Kidney Transplantation
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.*Methods: 19 patients with evidence of calcineurin inhibitor (CNI) toxicity…2020 American Transplant Congress
Improvement in Long Term Kidney Transplant Survival Most Dramatic among Minorities, Diabetics and Older Patients
*Purpose: Short-term and long-term kidney transplant graft survival has been improving over time, but whether this improvement in outcomes is more pronounced in the early…2020 American Transplant Congress
Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury
*Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…2020 American Transplant Congress
Temporal Trends in Utilization and Outcomes of Sclerotic Donor Kidneys in the United States
Johns Hopkins University, Baltimore, MD
*Purpose: Sclerotic donor kidneys (SDK, glomerulosclerosis ≥20% on biopsy) represent a possible expansion to the donor pool but are often discarded due to historical association…2020 American Transplant Congress
Conversion to Sirolimus to Prevent Recurrent Cytomegalovirus Infection/Disease: A Prospective and Randomized Trial
Hospital do Rim - UNIFESP, São Paulo, Brazil
*Purpose: Recurrent cytomegalovirus (CMV) infection occurs in 30-35% of kidney transplant recipients after completion of treatment and/or preemptive therapy. There is no consensus on the…2020 American Transplant Congress
Belatacept Provides Superior Inhibition of Donor Specific Antibody Formation in Kidney Transplant Recipients with Acute Rejection
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA
*Purpose: The factors responsible for chronic renal allograft dysfunction and premature graft loss are incompletely understood and likely multifactorial. Immunologic injury partially attributable to the…2020 American Transplant Congress
The Role of the Molecular Microscope to Guide Therapy for T-Cell Mediated Rejection in Kidney Transplants
1Virginia Commonwealth University, Glen Allen, VA, 2ATAGC, Edmonton, AB, Canada
*Purpose: Histologic lesions (I+T) to characterize T-cell mediated rejection (TCMR) can be non-specific. In some cases the inflammation may represent a ‘response to wounding’ rather…
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