2020 American Transplant Congress
Kidney Transplant from Sickle Cell Donors
University of Mississippi, Jackson, MS
*Purpose: Patients with End-stage renal disease have an increased risk of death. Dialysis and kidney transplantation are the only treatments. Patients who receive kidney transplantation…2020 American Transplant Congress
Kidney Transplantation for the Prevention of Aggravation of Peripheral Arterial Disease in the Diabetic Ischaemic Lower Limb. A Multicenter Propensity Score Matched Cohort Study in Japan
Division of Transplant Surgery, St. Mary Hospital, Kurume, Japan
*Purpose: Japan substantially outperforms other countries in survival of patients receiving haemodialysis (HD). Unadjusted 5-year survival was 60% in Japan, 39% in the USA, and…2020 American Transplant Congress
Patient Attitudes Regarding Contraception and Pregnancy after Transplantation
*Purpose: Professional society recommendations regarding contraception and pregnancy after transplantation exist but little is known about patient attitudes.*Methods: We conducted a survey of female transplant…2020 American Transplant Congress
Effect of Simultaneous Presence of Anti-Blood Group A/B and -HLA Antibodies on Clinical Outcomes in Kidney Transplantation Across Positive Crossmatch: A Nationwide Cohort Study
Department of General Surgery, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: ABO-incompatible (ABOi) and positive crossmatch (XM) kidney transplantation (KT) have been considered immunologically challenging. The present study analyzed the clinical outcomes in XM positive…2020 American Transplant Congress
Experience with a BKV-Specific, Neutralizing Monoclonal Antibody (MAU868) for Treatment of Severe BK Virus Nephropathy (BKVN) after Kidney Transplant (FDA EIND #139112)
*Purpose: BK viral reactivation leading to nephropathy and allograft loss in kidney transplant recipients remains a significant challenge. No effective BKV-therapies are currently available. Management…2020 American Transplant Congress
Pre-Transplant Pharmacogenetics Identifies CYP3A4 and CYP3A5 Heterogeneity among Caucasian Kidney Transplant Recipients
*Purpose: Tacrolimus has always been dosed based on therapeutic drug monitoring, however pharmacogenomics is becoming increasingly more utilized in the era of precision based medicine…2020 American Transplant Congress
Femto Pulse Analysis of Exosome RNA from Plasma of Renal Transplant Patients Confirmed the Unique Benefits of Plasma Exosome for Messenger RNA (mRNA) Transcript Analysis
*Purpose: Previously, we reported the feasibility of measuring the mRNA transcript levels of various genes in plasma exosomes of renal transplant patients for prediction of…2020 American Transplant Congress
Diagnostic Method of Acute Kidney Rejection after Transplantation Using Metabolome Analysis via a Liquid Biopsy Approach
*Purpose: At present, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy…2020 American Transplant Congress
A Multicenter, Randomized, Controlled Trial to Steer Immunosuppressive Therapy by Virus-Specific T Cells after Pediatric Kidney Transplantation (IVIST-Trial)
*Purpose: Pharmakokinetic monitoring of immunosuppressants alone is insufficient to estimate the individual intensity of immunosuppression after kidney transplantation (Tx). Virus-specific T cells (Tvis) correlate with…2020 American Transplant Congress
Kidney Paired Donation Outcomes among High PRA Recipients
1University of North Carolina, Chapel Hill, NC, 2Johns Hopkins, Baltimore, MD
*Purpose: Kidney paired donation (KPD) accounts for an increasing amount of living donor transplants in the US. Previous studies have shown equivalent outcomes between transplants…
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