Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Maternal Perinatal Condition and Neonatal Growth and Development After Renal Transplantation
X. Feng, T. Song, Q. Zhong, J. Zeng, X. Wang, Y. Fan, Z. Huang, T. Lin
Department of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, China
*Purpose: Although pregnancy and delivery after kidney transplantation have been reported in many studies , it is still little known about growth and development of…
2021 American Transplant Congress
Detection of Rejection in Kidney Transplant Patients Using an Algorithm That Combines Donor Fraction and Absolute Donor-derived Cell-free DNA
S. Bunnapradist¹, E. Ahmed², M. Maninder², Z. P. Demko², P. R. Billings², H. Tabriziani², P. Gauthier³
¹David Geffen Sch of Med @ UCLA, Los Angeles, CA, ²Natera, Inc., San Carlos, CA, ³Natera, Inc., Los Angeles, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft patients is a clinically validated biomarker for allograft injury and rejection. Several dd-cfDNA assays…
2021 American Transplant Congress
Characterization of Chronic Renal Allograft Dysfunction at Single Cell Resolution
C. Kuscu¹, C. Kuscu², A. Shetty³, M. Talwar⁴, J. Eason², D. G. Maluf⁵, V. Mas⁶
¹Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Institute for Genome Sciences, School of Medicine, University of Maryland, Baltimore, MD, ⁴Nephrology, James D Eason Transplant Institute, Memphis, TN, ⁵Surgery, Program in Transplantation - University of Maryland, Baltimore, MD, ⁶Surgery, Division of Surgical Science - University of Maryland, Baltimore, MD
*Purpose: Chronic allograft dysfunction (CAD) is one of the major complications after kidney transplantation. Hereby, we aim to assess the molecular and cellular mechanism of…
2021 American Transplant Congress
Regional Impact of Covid-19 on Kidney Transplant in the Southeast
C. Jay¹, B. Sharda¹, R. Helmick², R. Forbes³, V. Casingal⁴, R. Stratta¹
¹Wake Forest Baptist Health, Division of Abdominal Organ Transplantation, Winston-Salem, NC, ²University of Tennessee Health Science Center, James Eason Transplant Institute, Memphis, TN, ³Vanderbilt University Medical Center, Division of Kidney and Pancreas Transplantation, Nashville, TN, ⁴Atrium Health, Division of Transplant Surgery, Charlotte, NC
*Purpose: Despite categorization of kidney transplantation as Tier 3b with guidelines against postponing, the impact of the COVID-19 pandemic has been profound but geographically diverse.…
2021 American Transplant Congress
Development of De-novo Malignancies After Kidney and/or Pancreas Transplantation in Diabetic Patients
A. Gruessner, S. Saggi, J. Renz, R. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Transplantation of a kidney (KTA), pancreas (PTA), or a simultaneous pancreas-kidney (SPK) in a patient with end-stage organ failure is a lifesaving treatment. Patient…
2020 American Transplant Congress
Deceased Donors in Kidney Paired Donation
J. D. Kalbfleisch¹, W. Wang¹, M. A. Rees², A. B. Leichtman³, P. X. Song¹, V. Ashby¹, T. Shearon¹
¹Biostatistics, University of Michigan, Ann Arbor, MI, ²University of Toledo, Toledo, OH, ³University of Michigan, Ann Arbor, MI
*Purpose: A kidney paired donation pool (KPDP) consists of transplant candidates and their incompatible living donors along with nondirected living donors (NDDs). In a match…
2020 American Transplant Congress
Prospective, Randomized Study of Conversion from Calcineurin Inhibitor (CNI)- to Belatacept (BELA)-Based Maintenance Immunosuppression in Renal Transplant Recipients
K. Budde¹, R. Prashar², H. Haller³, M. Rial⁴, N. Kamar⁵, A. Agarwal⁶, J. de Fijter⁷, L. Rostaing⁸, S. Berger⁹, A. Djamali¹⁰, N. Leca¹¹, L. Allamassey¹², S. Gao¹², M. Polinsky¹², F. Vincenti¹³
¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Henry Ford Hospital, Detroit, MI, ³The Hannover Medical School, Hannover, Germany, ⁴Instituto de Nefrologia, Nephrology SA, Buenos Aires, Argentina, ⁵University of Toulouse, Toulouse, France, ⁶UVA Health, Charlottesville, VA, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Université Grenoble Alpes, Saint-Martin-d'Hères, France, ⁹University Medical Centre Groningen, Groningen, Netherlands, ¹⁰University of Wisconsin, Madison, WI, ¹¹UW Medical Center, Seattle, WA, ¹²Bristol-Myers Squibb, Princeton, NJ, ¹³University of California, San Francisco, San Francisco, CA
*Purpose: CNIs are associated with adverse systemic and nephrotoxic effects that negatively impact long-term patient and graft survival. In a phase 2 study, switching renal…
2020 American Transplant Congress
Pediatric Primary Kidney Transplant Recipients Outcomes by Immunosuppression Induction Received in the United States
S. M. Riad¹, S. Jackson², A. Matas³, S. Chinnakotla³, P. Verghese⁴
¹University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN, ⁴Pediatrics, University of Minnesota, Minneapolis, MN
*Purpose: Induction immunosuppression types for pediatric transplant recipients vary widely by transplant centers. We sought to study the impact of different induction types on recipients…
2020 American Transplant Congress
Survival of ESRD Patients with an EPTS > 90% Listed for Kidney Transplant
M. S. Sampaio¹, E. Lum¹, P. Homkrailas¹, G. Danovitch¹, H. Gritsch², S. Bunnapradist¹
¹UCLA - Division of Nephrology, Los Angeles, CA, ²UCLA - Division of Urology, Los Angeles, CA
*Purpose: Mortality on the kidney transplant waitlist is high especially in candidates with a high Estimated Post Transplant Survival (EPTS) score. We examined outcomes of…
2020 American Transplant Congress
Preferences of Potential Living Kidney Donors on Strategies to Reduce Donation-Related Financial Burden
A. D. Waterman¹, O. N. Ranasinghe¹, Y. Cui², J. L. Beaumont², D. Adey³, B. Campbell⁴, F. L. Weng⁵
¹Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³UCSF Health, San Francisco, CA, ⁴Cedars Sinai Medical Center, Los Angeles, CA, ⁵St. Barnabas Medical Center, Livingston, NJ
*Purpose: To identify the severity of financial and employment challenges present for potential living kidney donors and the value of strategies to make kidney donation…