Articles tagged "Kidney transplantation"

2021 American Transplant Congress
Value of a Personal Systems Approach in Improving Medication Adherence in Adult Kidney Transplant Patients: A Cost-effectiveness Analysis of the MAGIC Randomized Clinical Trial
M. R. Wakefield¹, M. Whittington², C. Ashbaugh³, L. M. Remy⁴, D. Aholt⁴, C. Miller⁴, D. Hathaway⁵, D. Clark⁵, K. Goggin⁵, R. J. Ellis⁶, C. L. Russell⁴
¹Surgery/Urology, University of Missouri School of Medicine, Columbia, MO, ²University of Kansas Medical Center, Kansas City, KS, ³University of Missouri Health Care, Columbia, MO, ⁴University of Missouri-Kansas City, Kansas City, MO, ⁵Children's Mercy Kansas City, Kansas City, MO, ⁶Indiana University School of Nursing, Indianapolis, IN
*Purpose: The objective of this evaluation was to estimate the cost of implementation and the cost-effectiveness of a person-level intervention called SystemCHANGETM .*Methods: To estimate…
2021 American Transplant Congress
Selective Bcl-2 Inhibition to Deplete Hematopoietic Stem Cells in Bone Marrow Niche: A Novel Approach to Promote Mixed Chimerism
T. Hirose¹, H. Sasaki¹, G. Lassiter¹, D. Ma¹, T. Oura¹, A. Dehnadi¹, A. Cosimi¹, P. Cippa², T. Fehr², T. Kawai¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Institute of Physiology, University of Zurich, Zurich, Switzerland
*Purpose: A recent murine study has shown that successful mixed chimerism is achievable without myelosuppressive treatments by Bcl-2 inhibition. However, the mechanism by which selective…
2021 American Transplant Congress
Brain Natriuretic Peptide and Pedometer Activity are Most Predictive of Poor Kidney Transplant Waitlist Outcomes
P. Manay¹, P. TenEyck², R. Kalil³, M. Sanders⁴, M. Swee⁴, G. Binns⁵, J. Hornikel⁵, D. Katz¹
¹Department of Surgery, University of Iowa, Iowa City, IA, ²Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA, ³Department of Medicine, University of Maryland Medical Center, Baltimore, MD, ⁴Department of Medicine, University of Iowa, Iowa City, IA, ⁵Iowa City VAMC, Iowa City, IA
*Purpose: Tools for indicating which patients are most at risk for complications and death after transplant listing would allow for a rational approach to targeted…
2021 American Transplant Congress
Donor Derived Cell-free-dna (dd-cfdna) as a Surrogate Marker for Kidney Biopsy- Indiana University Transplant Nephrology Experience
S. Valavoor¹, A. Sharfuddin², G. William³, M. Yaqub¹, D. Mishler¹, O. Adebiyi²
¹Nephrology, Indiana University, Indianapolis, IN, ²Transplant Nephrology, Indiana University, Indianapolis, IN, ³Transplant Surgery, Indiana University, Indianapolis, IN
*Purpose: Patient monitoring after kidney transplantation (KT) for early detection of allograft rejection remains key in preventing allograft loss. Donor-derived cell-free DNA (dd-cfDNA), a noninvasive…
2021 American Transplant Congress
Impact of Valganciclovir Prophylaxis Dosing in High Risk Cytomegalovirus Kidney and Pancreas Transplant Recipients with Delayed Graft Function
A. Gharabagi¹, J. Geyston¹, A. Agarwal², S. Rao³, A. Doyle³, J. Dann¹
¹Pharmacy, University of Virginia Health System, Charlottesville, VA, ²Transplant Surgery, University of Virginia Health System, Charlottesville, VA, ³Transplant Nephrology, University of Virginia Health System, Charlottesville, VA
*Purpose: We sought to compare outcomes of cytomegalovirus (CMV) prophylaxis in high risk CMV (donor +/recipient -) kidney and pancreas transplant recipients who received different…
2021 American Transplant Congress
Impact of Early versus Late Ureteric Stent Removal and Antibiotic Prophylaxis on Urinary Tract Infection Incidence in Kidney Transplant Adult Recipients
K. Althiab¹, B. Alqahtani², R. Alotaibi³, R. Alhussein³, R. Almuhiteb², L. Alnajjar², M. Alqahtani², K. Bin Saad⁴, W. Ohali⁴, A. Tamimi⁴, M. N. Almarastani⁴, S. Kashkoush⁴, G. Aboalsameh⁴, M. Shaheen⁴, M. Tawhari⁴, A. Altheaby⁴, Z. Arabi⁵
¹Pharmaceutical Care Services, King Abdulaziz Medical Center, Riyadh, Saudi Arabia, ²College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, ³bCollege of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, ⁴Organ Transplant Center, King Abdulaziz Medical Center, Riyadh, Saudi Arabia, ⁵King Abdulaziz Medical Center, Riyadh, Saudi Arabia
*Purpose: To investigate the impact of early Vs. late ureteric stent removal while utilizing various antibiotic prophylaxis regimens on UTI in renal transplant recipients. *Methods:…
2021 American Transplant Congress
Risk Factors Associated with Multidrug Resistant Organism (MDRO) Infections in Kidney Transplant Recipients: A Single Center Experience
S. Schrank¹, J. Timpone², B. Javaid³, P. Kumar², M. Cooper³
¹Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, ²Infectious Diseases and Travel Medicine, MedStar Georgetown University Hospital, Washington, DC, ³Transplant Institute, MedStar Georgetown University Hospital, Washington, DC
*Purpose: Risk factors for MDRO infections in kidney transplant recipients have previously been studied but limited to urinary tract infections. We sought to evaluate the…
2021 American Transplant Congress
HLA Haplotype Frequency and Racial Disparities in Access to Transplant Among Highly Sensitized Kidney Transplant Candidates
L. Gragert¹, M. Kadatz², D. Chang², H. Gebel³, D. Stewart⁴, E. Kransdorf⁵, S. Brar², S. Vaishnav², J. Gill², J. Lan²
¹Tulane University, New Orleans, LA, ²University of British Columbia, Vancouver, BC, Canada, ³Emory University, Atlanta, GA, ⁴UNOS, Richmond, VA, ⁵Cedars-Sinai, Beverly Hills, CA, Canada
*Purpose: Despite implementation of the Kidney Allocation System (KAS) which prioritizes sensitized patients, sensitized Black individuals are less likely to receive a transplant than non-Black…
2021 American Transplant Congress
The Implications of Donor-Recipient Size Mismatch in Renal Transplantation
I. D. Kostakis, N. Karydis, T. Kassimatis, N. Kessaris, I. Loukopoulos
Department of Transplantation, Guy’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom
*Purpose: Transplanting kidneys small for the recipient’s size results in inferior renal graft function. Body surface area (BSA) is related to kidney size. We used…
2021 American Transplant Congress
Experiential Expertise: What Can Patients and Donors Teach Us About Living Donation?
L. A. Davis¹, E. H. Wood², E. Ho³, R. Pines⁴, S. M. Advani⁵, A. D. Waterman²
¹DeSales University, Center Valley, PA, ²UCLA David Geffen School of Medicine, Los Angeles, CA, ³Terasaki Institute, Los Angeles, CA, ⁴Santa Barbara Cottage Hospital, Santa Barbara, CA, ⁵National Human Genome Research Institute, NIH, Bethesda, MD
*Purpose: While educational materials and discussions with medical professionals are factually sound, insight from actual living donors (LDs) and recipients (Rs) may offer unique, experiential…