ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Intimal"

  • 2022 American Transplant Congress

    Progression of Peripheral Vascular Disease After Kidney/Pancreas Transplantation

    R. J. Knight, E. A. Graviss, D. T. Nguyen, Y. Ye, S. G. Yi, C. S. Bavare, A. R. Sadhu, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: It is unclear whether kidney/pancreas (KP) transplantation will prevent the progression of peripheral vascular disease in patients with IDDM and ESRD. We sought to…
  • 2022 American Transplant Congress

    Deep Learning Identifies Arterial Intimal Fibrosis in Kidney Transplant Biopsies

    K. Liu1, Z. Yi2, S. Ward3, F. Salem3, W. Zhang2

    1Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 3Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Arterial intimal fibrosis (AIF) is the excessive fibrotic tissue formation in the intima of arteries indicative of poor graft function after kidney transplant. Visual…
  • 2020 American Transplant Congress

    Intimal Arteritis in Association with Microvascular Inflammation Leads to Inferior Graft Survival Regardless DSA

    M. Novotny1, E. Honsova2, O. Viklicky1

    1Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Intimal arteritis belongs between diagnostic criteria of both antibody-mediated rejection (AMR) and T cell-mediated vascular rejection (TCMRV). Patients with intimal arteritis must be assessed…
  • 2020 American Transplant Congress

    Impact of Alemtuzumab Induction on Cardiac Allograft Vasculopathy in Orthotopic Heart Transplant Recipients

    M. Plazak1, X. Gao2, S. Gale2, B. Reed2, R. Madathil1, S. Hammad1, B. Ravichandran1

    1University of Maryland Medical Center, Baltimore, MD, 2University of Maryland School of Pharmacy, Baltimore, MD

    *Purpose: Cardiac allograft vasculopathy (CAV) is impacted by acute rejection and ultimately limits long-term survival of orthotopic heart transplant (OHT) recipients, thus there is interest…
  • 2019 American Transplant Congress

    Apoptotic Exosome-Like Vesicles Induce Endothelial Cell Plasticity and Accelerate Allograft Vascular Remodeling

    F. Migneault1, M. Dieudé1, J. Turgeon1, A. Karakeussian Rimbaud1, D. Beillevaire1, M. Hardy2, A. Brodeur1, N. Thibodeau1, C. Perreault2, M. Hébert1

    1CRCHUM, Montreal, QC, Canada, 2IRIC, Montreal, QC, Canada

    *Purpose: Acute vascular rejection of allografts is associated with endothelial apoptosis which in turn contributes to the development of transplant vasculopathy. We previously showed that…
  • 2019 American Transplant Congress

    More Than Meets the Eye: The Use of Serial Intravascular Ultrasound for Assessment of Cardiac Allograft Vasculopathy after Heart Transplantation

    Y. Moayedi1, C. Fan2, M. Tremblay-Gravel1, R. J. Miller1, M. Kawana1, J. Parizo1, G. Oro1, R. Wainwright1, H. I. Luikart1, N. D'Emilio1, J. Gordon1, R. Kameda1, M. Ikutomi1, C. Manlhiot1, W. F. Fearon1, H. J. Ross1, K. K. Khush1, J. J. Teuteberg1

    1Stanford University, Palo Alto, CA, 2University of Toronto, Toronto, ON, Canada

    *Purpose: Cardiac allograft vasculopathy (CAV) is the “Achilles heel” of long-term survival after heart transplantation. While conventional coronary angiography is recognised as the standard for…
  • 2019 American Transplant Congress

    Slowed Progression of Maximal Intimal Thickening by Intravascular Ultrasound after Initiation of Sirolimus

    A. Putschoegl1, K. Campbell1, M. Everitt1, S. Miyamoto1, B. Pietra2, S. Auerbach1

    1Children's Hospital Colorado, Aurora, CO, 2University of Florida Health, Gainesville, FL

    *Purpose: Evidence in adult heart transplant (HT) patients (pt) shows that initiating sirolimus (SRL) slows progression of cardiac allograft vasculopathy (CAV) measured by intravascular ultrasound…
  • 2018 American Transplant Congress

    Apoptotic Exosome-Like Vesicles Induce Endothelial Cell Plasticity

    F. Migneault,1,2,4 M. Dieudé,1,2,4 J. Turgeon,1,4 D. Beillevaire,1,2,4 M-.P. Hardy,2,3,4 C. Perreault,2,3,4 M-.J. Hébert.1,2,4

    1CRCHUM, Montreal, QC, Canada; 2Université de Montréal, Montreal, QC, Canada; 3IRIC, Montreal, QC, Canada; 4CNTRP, Montreal, QC, Canada.

    Acute vascular rejection of renal allografts is associated with increased endothelial apoptosis which contributes to the development of transplant vasculopathy. We previously showed that apoptotic…
  • 2015 American Transplant Congress

    Intimal Arteritis Associated With Subsequent Graft Dysfunction in ABO-Incompatible Kidney Transplantation

    D. Toki,1 H. Iahida,1 M. Okumi,1 T. Shimizu,1 M. Inui,1 K. Omoto,1 H. Shirakawa,1 K. Unagami,1 K. Honda,2 J. Koike,3 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Pathology, Tokyo Women's Medical University, Tokyo, Japan; 3Pathology, Tama Hospital, Kanagawa, Japan.

    Purpose: The diagnosis of acute antibody-mediated rejection (ABMR) is according to following all three evidences: 1) histologic evidence , 2) evidence of interaction with vascular…

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