2015 American Transplant Congress
Establishment of Diabetes Modeling in Common Marmoset
Background:Diabetic nonhuman primates (NHPs) are considered as the good models for both diabetes mellitus research and islet transplantation research safely into clinical applications. However, there…2015 American Transplant Congress
Effect of Living Kidney Donation on Glucose Metabolism and Insulin Resistance
The kidney contributes to glucose hemostasis through processes of insulin metabolism, gluconeogenesis, and glucose filtration. Little is known on insulin sensitivity in living kidney donors…2015 American Transplant Congress
Long-Term Metabolic Outcomes of Functioning Pancreas Transplants in Type 2 Diabetic Recipients
Asan Medical Center, Seoul, Korea.
Background Limited data are available on long-term metabolic outcomes of functioning pancreas transplants in patients with type 2 diabetes mellitus (T2DM). The aim of this…2015 American Transplant Congress
Is BMI of 28 an Appropriate Cutoff for Simultaneous Pancreas Kidney Transplant in Type II Diabetes?
Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.
In simultaneous pancreas and kidney (SPK) transplantation, obesity has been reported to be associated with inferior survival and increased post-transplant complications. With implementation of the…2015 American Transplant Congress
Pancreas After Failed Islet Transplantation; a Successful Strategy to Maintain Insulin Independence
Introduction: As islet transplantation (tx) remains an experimental and uninsured procedure, there are no established protocols to achieve insulin independence following failure of the islet…2015 American Transplant Congress
Human iPS Cell-Derived Pancreatic β-Cells Correct Hyperglycemia in Diabetic Mice
Type I diabetes (T1D) is an autoimmune disorder that leads to the destruction of pancreatic β-cells. The consequences of T1D are dysregulation of metabolism leading…2015 American Transplant Congress
Pancreatic Islet Survival Under Confinement
UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.
The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
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