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Articles tagged "Infection"

  • 2016 American Transplant Congress

    Human MicroRNA Responses Are Predictive of CMV Reactivation Following Solid Organ Transplant.

    S. Han,1 D. Kumar,1 V. Ferreira,1 S. Husain,1 N. Mueller,2 A. Humar,1 M. Mian,1 P. Ashton.1

    1Multi Organ Transplant Program, University Health Network, Toronto, Canada; 2Swiss Transplant Cohort Study, University Hospital Zurich, Zurich, Switzerland.

    Background: Human microRNA (miRNA) can suppress gene expression through binding to the 3' untranslated region (UTR) of the target mRNA. In silico analysis shows that,…
  • 2016 American Transplant Congress

    Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.

    S. Bhutani,1 A. Ponnusamy,2 Q. Tak,1 S. Shah,1 J. Worthington,1 A. Summers,1 K. Poulton,1 D. Van Dellen,1 M. Morton,1 M. Picton.1

    1Department of Renal & Transplant Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Department of Renal Medicine, Royal Hospital Preston, Preston, United Kingdom.

    Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
  • 2016 American Transplant Congress

    Adenovirus Infection in Kidney Transplant Recipients: Report of a Case Series.

    C. Simancas-Ruiz, L. Marino-Vazquez, A. Meraz-Muñoz, A. Nuñez-Abreu, R. Rivera-Marfil, N. Uribe-Uribe, J. Alberu, L. Morales-Buenrostro.

    Nephrology, Transplant and Pathology, National Institute of Medical Sciences and Nutrition SZ, México, DF, Mexico.

    Introduction: In kidney transplant recipients, the incidence of adenovirus infection is 4.1%, usually occur in the first three months after transplantation. Patients may have viral…
  • 2016 American Transplant Congress

    Donor-Derived Toxoplasmosis in Solid Organ Transplant 2008 – 2015: Opportunities for Improvement.

    C. Wolfe,1 A. Wilk,2 S. Tlusty,2 C. Sifri,1 M. Morris,1 A. Mehta,1 D. Kaul.1

    1DTAC, Richmond, VA; 2United Network for Organ Sharing, Richmond, VA.

    Background: Donor-derived Toxoplasmosis (DDT) is uncommon, but outcomes may be poor. Donor risk factors are difficult to recognize, and donor screening is not currently universally…
  • 2016 American Transplant Congress

    Do Powerful Induction Antibodies Increase Post Renal Transplant Infections?

    M. John, I. Dortonne, B. Kim, C. Li, M. Killackey, A. Paramesh, B. Lee, R. Zhang, G. Parker, J. Buell.

    Transplant Institute, Tulane University School of Medicine, New Orleans, LA.

    Purpose: Infection is one of the most common and costly complications of solid organ transplantation. Alemtuzemab (AL) is a powerful antibody that significantly reduced rejection…
  • 2016 American Transplant Congress

    Profiling Metabolic Differences Between Graft- vs. Pathogen-Elicited CD8+ T Cell Responses.

    A. Karp, M. Wagener, J. Robertson, M. Ford.

    Emory University, Atlanta.

    The challenge of immune modulation in transplantation is to inhibit pathologic alloreactivity while minimizing off-target toxicities and preserving protective immunity. Data have emerged demonstrating the…
  • 2016 American Transplant Congress

    Outcomes of Hispanic Kidney Transplant Recipients Under a Cyclosporine versus Tacrolimus Based Immunosuppression Protocol.

    P. West-Thielke, A. Lasky, J. Thielke, M. Campara, E. Benedetti.

    University of Illinois, Chicago.

    Purpose: In 2005, an internal retrospective study at our institution showed a higher incidence of post transplant diabetes mellitus (PTDM) in our Hispanic kidney transplant…
  • 2016 American Transplant Congress

    Characteristics of Human Rhinovirus (HRV) Infections in Transplant Recipients.

    H. Crossman,1 M. Barron,1 M. Levi.1

    1University of Colorado School of Medicine, Univ of Colorado Denver, Aurora, CO; 2Internal Medicine/Infectious Diseases, Univ of Colorado Denver, Aurora, CO; 3Internal Medicine/Infectious Diseases, Univ of Colorado Denver, Aurora, CO.

    Introduction:Although HRV is a common cause of benign upper respiratory infection, there are reports of HRV resulting in lower respiratory tract infection (LRTI) in HSCT…
  • 2016 American Transplant Congress

    Significance of Preservation Fluid Cultures in Solid Organ Transplantation.

    H. Nam, N. Perni, K. Galen, M. Campara, R. Roca-Garcia, V. Yeldandi.

    University of Illinois at Chicago, Chicago.

    Introduction. The study aim was to determine microbiological characteristics of preservation fluid (PF) cultures in solid organ transplant (SOT) patients and to evaluate their impact…
  • 2016 American Transplant Congress

    Evaluation of the Utilization of Filgrastim in Kidney Transplant Recipients.

    T. Poon,1 C. Guerra.2

    1Pharmacy, Long Island University, Brooklyn, NY; 2Pharmacy, SUNY Downstate Medical Center, Brooklyn, NY.

    Purpose: Granulocyte colony-stimulating factors (G-CSF), such as filgrastim, stimulate the production, proliferation, and differentiation of neutrophils and are indicated for the treatment of neutropenia in…
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