Articles tagged "Infection"

2016 American Transplant Congress
Characterization of Resistant Cytomegalovirus in Lung Transplant Recipients in the Modern Era.
S. Hammad, L. Shah, M. Restivo, H. Robbins, J. Scheffert.
NewYork-Presbyterian Hospital, New York, NY.
Cytomegalovirus (CMV) remains a major cause of morbidity and mortality in lung transplant recipients (LTR) and the emergence of resistant CMV (rCMV) has increased. The…
2016 American Transplant Congress
Pneumocystis Pneumonia Following Solid Organ Transplantation, Systematic Review and Meta-Analysis.
S. Hosseini-Moghaddam,^1,2 R. Krishnan.²
¹Medicine, Western University, London, ON, Canada; ²Epidemiology and Biostatistics, Western University, London, ON, Canada.
Background: Different variables have been reported that may increase the risk of pneumocystis pneumonia (PCP) in solid organ transplant patients (SOT).Objectives:To investigate the effect of…
2016 American Transplant Congress
Vaccination Status and Titers Before and After Pediatric Renal Transplantation: An Analysis of the CERTAIN Registry.
B. Höcker,¹ M. Aguilar,¹ P. Schnitzler,² L. Pape,² L. Dello Strologo,² N. Webb,² M. Bald,² G. Genc,² H. Billing,² J. König,² A. Büscher,² F. Thiel,² S. Marks,² M. Pohl,² M. Wigger,² R. Topaloglu,² A. Fichtner,¹ S. Rieger,¹ K. Krupka,¹ B. Tönshoff.¹
¹University Children's Hospital, Heidelberg, Germany; ²CERTAIN Research Community, Italy, United Kingdom, Turkey, Germany.
Purpose:Prevention of systemic viral and bacterial infections by effective vaccination in kidney allograft recipients is of vital importance, but data on the vaccination status in…
2016 American Transplant Congress
Impact of Morbid Obesity on Breakthrough CMV Infection in Kidney Transplant Recipients.
S. Strout, N. Pilch, T. Veasey, R. Miller, J. Fleming, H. Meadows, C. Mardis, B. Mardis, P. Baliga, K. Chavin, D. Taber.
Medical University of South Carolina, Charleston, SC.
Purpose: The aim of this study was to assess the impact of obesity on risk for cytomegalovirus (CMV) infection after kidney transplantation as well as…
2016 American Transplant Congress
The Impact of Pre-Transplant Infections on Post-Liver Transplant Outcomes.
S. Ngo, J. Levitsky, M. Ison.
Divisions of Infectious Diseases, Hematology and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL.
Background: Pre- and Post-liver transplant infections are a common cause of morbidity and mortality in orthotopic liver transplant (OLT) patients. How pre-transplant infections affect early…
2016 American Transplant Congress
An Analysis of Non-Tuberculous Mycobacteria (NTM) Infection and Colonization in Lung Transplant Recipients (LTRs) Post-Transplant: A Single Center Matched Cohort Study.
H. Kozlowski,^1,2 D. Kabbani,³ C. Chaparro,^1,2 L. Singer,^1,2 C. Rotstein,^1,2 S. Keshavjee,^1,2 S. Husain.^1,2
¹University of Toronto, Toronto, ON, Canada; ²Toronto General Hospital, Toronto, ON, Canada; ³University of Alberta, Edmonton, AB, Canada.
PurposeNTM is a common infection after Lung transplantation. The role of presence of granuloma in the explanted lungs of LTRs in subsequent development of infection…
2016 American Transplant Congress
Three Months of Weekly Rifapentine Plus Isoniazid for Latent Tuberculosis Treatment in Solid Organ Transplant Candidates.
B. Knoll,¹ R. Nog,¹ Y. Wu,² A. Dhand.¹
¹Medicine, Division of Infectious Diseases, Westchester Medical Center, Valhalla, NY; ²Division of Transplant and Hepatobiliary Surgery, Westchester Medical Center, Valhalla, NY.
Purpose: Although isoniazid 300 mg daily for 9 months is the recommended regimen for latent tuberculosis infection (LTBI) in solid organ transplant (SOT) candidates, its…
2016 American Transplant Congress
Low Pretransplant BMI/Weight and Changes in Posttransplant T Cell Exhaustion Levels Are Associated with Viremia/Viral Infection in Pediatric Kidney Transplantation in the First Post-Transplant Year – A Report from the IMPACT Study Consortium.
R. Ettenger,¹ H. Chin,² P. Grimm,³ K. Kesler,² E. Reed,⁴ M. Sarwal,⁵ B. Warshaw,⁶ E. Tsai,¹ A. Kirk.⁷
¹Pediatrics, UCLA, LA, CA; ²Rho, Chappel Hill, NC; ³Pediatrics, Stanford Univ, Palo Alto, CA; ⁴Pathology, UCLA, LA, CA; ⁵Surgery, UCSF School of Medicien, SF, CA; ⁶Pediatric Nephrolgoy, Children's Healthcare of Atlanta, Atlanta, GA; ⁷Surgery, Duke University, Durham, NC.
Viral consequences of immunosuppression (IS) in pediatric(ped)kidney(kid)transplantation(Tx)patients(pts) are not fully known. We prospectively examined the immunologic and infectious (inf) history of 106 ped Tx pts…
2016 American Transplant Congress
Evaluation of a Novel Global Immunity Assay to Predict Infections in Organ Transplant Recipients.
M. Mian, A. Humar, S. Keshwani, S. Husain, P. Ashton, S. Han, L. Singer, J. Kim, E. Renner, M. Bhat, D. Kumar.
Multi-Organ Transplant, University Health Network, Toronto, Canada.
BackgroundSimple standardized measures of global immunity may help predict the risk of infections post-transplant. The Quantiferon-Monitor (QFM) test is a novel interferon-γ (IFN-γ) release assay…
2016 American Transplant Congress
Clinical Impact of the Verigene® Blood Culture System on Rapid Diagnosis and Antibiotic Optimization in Bacteremic Solid Organ Transplant (SOT) Recipients.
N. Law,¹ G. Malat,^3,4 D. Lee,¹ A. Doyle,² C. Emery,^1,5 K. Kyle,⁵ K. Ranganna,² M. Harhay,² T. Bias.^1,4
¹Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, PA; ²Division of Nephrology, Drexel University College of Medicine, Philadelphia, PA; ³Department of Surgery, Drexel University College of Medicine, Philadelphia, PA; ⁴Pharmacy, Hahnemann University Hospital, Philadelphia, PA; ⁵Microbiology, Hahnemann University Hospital, Philadelphia, PA.
Background:Bloodstream infections are a major concern in SOT recipients and ineffective antibiotic therapy is strongly associated with poor outcomes. Rapid diagnostic tests (RDT) provide prompt…