ATC Abstracts

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Articles tagged "Infection"

  • 2016 American Transplant Congress

    Gene Expression Profiling Score and the Risk of Infection in Heart Transplant Recipients.

    J. Teuteberg,1 D. Budge,2 M. Shullo,1 S. Hall,3 J. Kobashigawa.4

    1University of Pittsburg, Pittsburgh, PA; 2Intermountain Medical Center, South Lake City, UT; 3Baylor University Medical Center, Dallas, TX; 4Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: This study assessed the association of gene expression profiling (GEP, AlloMap®) score with infections in heart transplant recipients (HTR). Although a GEP score below…
  • 2016 American Transplant Congress

    Parameters of Uremia-Associated Premature Ageing of Peripheral T Cells Do Not Predict Infectious Complications After Renal Transplantation.

    B. Dedeoglu, R. Meijers, M. Klepper, D. Hesselink, C. Baan, N. Litjens, M. Betjes.

    Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Centre, Rotterdam, Netherlands.

    Background: End-stage renal disease (ESRD) patients have a prematurely aged T-cell system, which may contribute to the uremia-associated immune deficiency. In this study we tested…
  • 2016 American Transplant Congress

    Incidence of Infectious Disease and Malignancies After Rituximab Therapy in Kidney-Transplant Recipients.

    E. Schrezenmeier,1 T. Doerner,2 O. Staeck,1 K. Budde,1 F. Halleck.1

    1Nephrology, Charité, Berin, Germany; 2Rheumatology, Charité, Berlin, Germany.

    BACKGROUND:Rituximab off-label use is common in solid organ transplantation. It is used in patients with antibody-mediated rejections, in AB0-incompatible renal transplantation, in pre-sensitized organ recipients…
  • 2016 American Transplant Congress

    Potential Applications of Viral miRNA Assays in the Management of Transplant Patients with Polyomavirus BK Infection.

    P. Randhawa, G. Zeng, Y. Huang.

    Department of Pathology, The Thomas E Starzl Transplant Institute, University of Pittsburgh, Pittsburgh, PA.

    Background: BKV encodes two miRNAs from a single precursor: BKV-miR-B1-5p & BKV-JCV-miR-BJ1-3p. These viral miRNAs direct cleavage of large T antigen mRNAs, downregulate viral T…
  • 2016 American Transplant Congress

    Characteristics and Outcomes of Vancomycin Resistant Enterococcus Bacteremia After Liver Transplant.

    R. Odrobina,1 C. Kovacs,1 R. Butler,2 C. Koval.1

    1Department of Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    Vancomycin Resistant Enterococcus (VRE) infection is reported in 5-20% of liver transplant (LT) recipients and is associated with decreased survival. Published data includes infections of…
  • 2016 American Transplant Congress

    Clostridium difficile Infection in Patients with a Continuous Flow, Durable Left Ventricular Assist Device.

    J. Glick Frasiolas, I. Li, H. Kim, D. Tsapepas.

    NewYork-Presbyterian Hospital, Columbia University, New York.

    Clostridium difficile infection (CDI) increases morbidity and mortality in hospitalized patients. Patients with a ventricular assist device (VAD) are exposed to known risk factors for…
  • 2016 American Transplant Congress

    Late-Onset Pneumocystis Jirovecii Pneumonia After Renal Transplantation: A Case-Control Study.

    J. Lee,1 J. Lee,1 S. Song,1 J. Lee,1 S.-K. Kwon,1 B. Kim,2 M. Kim,1 S. Kim,1 Y. Kim,1 K. Huh.1

    1Surgery, Yonsei University College of Medicine, Seoul, Korea; 2Internal Medicine (Nephrology), Yonsei University College of Medicine, Seoul, Korea.

    BackgroundPneumocystis jirovecii pneumonia (PCP) usually occurs during the first year after solid organ transplantation. Introduction of routine prophylaxis have reduced the incidence of PCP drastically.…
  • 2016 American Transplant Congress

    Impact of Everolimus and Low-Dose Ciclosporin on Cytomegalovirus Replication and Disease in Pediatric Renal Transplantation.

    B. Höcker,1 S. Zencke,1 L. Pape,2 K. Krupka,1 L. Kösters,1 A. Fichtner,1 L. Dello Strologo,2 I. Guzzo,2 R. Topaloglu,2 B. Kranz,2 J. König,2 M. Bald,2 N. Webb,2 A. Noyan,2 H. Dursun,2 S. Marks,2 Z. Ozcakar,2 F. Thiel,2 H. Billing,2 M. Pohl,2 H. Fehrenbach,2 P. Schnitzler,1 T. Bruckner,1 L. Weber,2 R. Feneberg,2 T. Ahlenstiehl-Grunow,2 B. Tönshoff.1

    1University Children's Hospital, Heidelberg, Germany; 2Certain Research Community, Germany, Italy, Turkey, United Kingdom.

    Purpose: Preclinical studies indicate an anti-cytomegalovirus (CMV) activity of the mammalian target of rapamycin inhibitor (mTORi) everolimus (EVR), but data in pediatric renal transplant recipients…
  • 2016 American Transplant Congress

    Variation in Co-Medication Use According to Kidney Transplant Immunosuppressive Regimen: Application of Integrated Registry and Pharmacy Claims Data.

    K. Lentine,1 A. Naik,2 M. Schnitzler,1 D. Axelrod,3 J. Chen,1 D. Brennan,4 D. Segev,5 B. Kasiske,6 H. Randall,1 V. Dharnidharka.4

    1Saint Louis Univ, St. Louis; 2Univ Michigan, Detroit; 3Dartmouth Univ, Hanover; 4Washington Univ, St. Louis; 5Johns Hopkins Univ, Baltimore; 6Univ Minnesota, Minneapolis.

    Background: While modern immunosuppressive therapies (ISx) have substantially reduced acute rejection, ISx medications have many side effects, and transplant recipients must take an array of…
  • 2016 American Transplant Congress

    Colonization and Risk of Bacteremia by Multi-Drug Resistant Organisms in Intestinal Transplant Recipients.

    J. Simkins,1 J. Camargo,1 M. Morris,1 R. Vianna,2 T. Beduschi,2 L. Abbo.1

    1Medicine/Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; 2Surgery, Miami Transplant Institute/University of Miami, Miami, FL.

    Background: This study is the first to evaluate colonization rates and subsequent bacteremia with multi-drug resistant organisms (MDRO) in intestinal transplant (ITx) recipients.Methods: Retrospective study…
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