2017 American Transplant Congress
Factors in Association with Sepsis Differ Between Simultaneous Pancreas/Kidney and Single Kidney Transplant Recipients.
As immunosuppressive therapy and allograft survival have improved in simultaneous pancreas/kidney transplant recipients (SPKTRs), the increased incidence of infection has become a major hurdle of…2017 American Transplant Congress
NFAT-Regulated Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Recipients – A Randomized Controlled Trial.
Purpose: To demonstrate that a pharmacodynamics assay using Real Time (RT)-PCR to measure residual expression (RE) of nuclear factor of activated T cell (NFAT)-dependent cytokines…2017 American Transplant Congress
Transplantation of Organs from Donors with Hepatitis C: The Potential to Substantially Increase Transplant Activity.
Introduction. Organs from hepatitis C virus positive (HCV+ve) donors are commonly declined for transplantation because of the risk of disease transmission, but new direct acting…2017 American Transplant Congress
Donor Factors Show Low Impact on Patient and Kidney Allograft Outcomes: A Paired Analysis of Left/Right Deceased Donor Kidney Pairs.
The impact of donor factors on kidney allograft outcomes and infectious complications has been suggested in many previous studies. However, analyses of left/right donor kidney…2017 American Transplant Congress
Incidence of Cytomegalovirus Infection Among Liver Transplant Recipients Maintained on a Cyclosporine vs. Tacrolimus-Based Immunosuppression Regimen.
The Ohio State University Wexner Medical Center, Columbus, OH
Background: Cytomegalovirus (CMV) is the most common viral pathogen that affects patient outcomes after liver transplant. Potent immunosuppressive agents predispose patients to an increased risk…2017 American Transplant Congress
Antibiotic Conservatorship in Orthotopic Liver Transplantation.
Post-orthotopic liver transplantation (OLT) infections, especially multidrug resistant organisms (MDRO), are implicated in poorer outcomes, fueling efforts to elucidate risk factors for hospital acquired infections.…2017 American Transplant Congress
Total Pancreatectomy and Islet Autotransplantation into the Liver of a Patient with Previous Hepatitis C Infection.
Hepatic parenchymal disease such as hepatitis has been considered a relative contraindication to islet transplantation as the islets are infused into the liver. Islet transplantation…2017 American Transplant Congress
Acute Mouse CMV Infection Abrogates Transplant Tolerance by Modulating Myeloid Cell Differentiation and Function: A Possible Role for Transcription Factor RORγt.
Cytomegalovirus (CMV) infection has long been associated with graft-dysfunction and rejection in transplant-recipients. Nevertheless, precise understanding of underlying molecular mechanisms remains unclear. Here, we investigated…2017 American Transplant Congress
Clinically Relevant Immunosuppression Promotes MCMV Reactivation and Dissemination Following Transplantation of Latently Infected Kidneys.
Reactivation of latent Cytomegalovirus (CMV) is an important problem facing clinical transplantation. We have previously described a model for murine CMV (MCMV) reactivation following kidney…2017 American Transplant Congress
Improving Donor Screening for Cytomegalovirus (CMV): Is CMV IgG Avidity Better Than CMV IgM?
Study purpose: It is standard practice to test organ donors for CMV IgM as a marker of recent CMV infection (defined as primary infection within…
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