Articles tagged "Infection"

2018 American Transplant Congress
Outcome Analysis of Renal Re-Transplantation Compared to a Matched Control Group of First Transplantation
A. Schwarz,¹ F. Schaefer,¹ T. Framke,² S. Linnenweber,¹ H. Haller.¹
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Biostatistics, Hannover Medical School, Hannover, Germany.
Background: 15% of our renal transplant program is re-transplantation (Tx2). We aimed to know if Tx2 has a higher risk than first transplantation (Tx1) and…
2017 American Transplant Congress
Uromodulin and Toll-Like Receptor 4 Levels Predict Susceptibility to Bacterial Urinary Tract Infection After Renal Transplantation.
K. Stahl,¹ H. Lührs,¹ J. Schmitz,² I. Scheffner,¹ W. Gwinner,¹ J. Bräsen,² H. Haller,¹ M. Schiffer.¹
¹Internal Medicine, Nephrology, Hannover Medical School, Hannover, Germany; ²Pathology, Hannover Medical School, Hannover, Germany
Background: Urinary tract infection (UTI) remains the most common bacterial infection after kidney transplantation (kTx) and is associated with reduced allograft function as well as…
2017 American Transplant Congress
Early Outcomes of Kidney Transplantation When Comparing Waist-to-Hip Ratio vs. Body Mass Index.
R. Patankar,¹ A. Gamilla-Crudo,¹ K. Gugliuzza,² O. Salim,³ S. Shah,¹ F. Ikram,⁴ M. Mujtaba.¹
¹Division of Nephrology and Hypertension, University of Texas Medical Branch, Galveston, TX; ²Department of Surgery, University of Texas Medical Branch, Galveston, TX; ³Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX; ⁴University of Texas Medical Branch, Galveston, TX
Introduction - High body mass index (BMI) is a concern for kidney transplantation due to wound infections and other surgical complications. BMI has been used…
2017 American Transplant Congress
De Novo Use of Everolimus Reduces Late-Onset Cytomegalovirus Primary Disease Occurring After Antiviral Prophylaxis Discontinuation in Kidney Transplant Recipients.
A. Devresse,¹ V. Avettand-Fenoel,² A. Scemla,³ L. Morin,³ X. Lebreton,³ C. Tinel,³ L. Amrouche,³ L. Lamhaut,⁴ M.-O. Timsit,⁵ J. Zuber,³ C. Legendre,³ D. Anglicheau.³
¹Nephrology Unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium; ²Virology Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; ³Kidney Transplantation and Intensive Care Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; ⁴Anesthesia Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; ⁵Urology Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
Background: Donor (D)+/recipient (R)- serostatus is critically associated with an higher risk of cytomegalovirus (CMV) infection and disease. Antiviral prophylaxis is conventionally used in such…
2017 American Transplant Congress
The Combined Effects of Induction Regimens and Antiviral Prophylaxis on the Risk of CMV Infection in Different Serostatus Subgroups After Liver Transplantation.
C. Low,² S. Hosseini-Moghaddam,^1,2 C. Rotstein,² E. Renner,² A. Humar,² D. Kumar,² S. Husain.²
¹Medicine, Western University, London Health Sciences Centre, London, Canada; ²University Health Network, Toronto, Canada
Introduction: Simultaneous effects of anti-CMV prophylaxis and induction regimens on cytomegalovirus (CMV) infection after liver transplantation (LTRs) have not been studied. We determined the magnitude…
2017 American Transplant Congress
Clinical Utility of Viral miRNA in Urinary Exosomes to Diagnose BK Virus Nephropathy After Kidney Transplantation.
J.-W. Seo,¹ Y. Lee,¹ H. Moon,¹ Y. Kim,¹ K.-H. Jeong,¹ J.-Y. Moon,¹ C.-D. Kim,² J. Park,³ B. Chung,⁴ Y.-H. Kim,⁵ S.-H. Lee.¹
¹Department of Nephrology, Kyung Hee University School of Medicine, Seoul, Republic of Korea; ²Department of Nephrology, Kyungpook National University Hospital, Daegu, Republic of Korea; ³Department of Nephrology, Samsung Medical Center, Seoul, Republic of Korea; ⁴Department of Nephrology, The St.Mary's Hospital of Catholic University College of Medicine, Seoul, Republic of Korea; ⁵Nephrology, Inje University College of Medicine, Pusan, Republic of Korea
Polymerase chain reaction (PCR) demonstration of BK viral replication in plasma and urine supports the diagnosis of BK virus nephropathy (BKVN), an important cause of…
2017 American Transplant Congress
Outcomes of Active Screening for Carbapenem-Resistant Enterobacteriaceae among Liver Transplant Recipients.
T. Bias,¹ G. Malat,¹ D. Lee,² S. Talluri,² K. Ranganna,² S. Epstein,² V. Patel,² S. Guy.³
¹Department of Pharmacy, Drexel University College of Medicine, Philadelphia, PA; ²Department of Medicine, Drexel University College of Medicine, Philadelphia, PA; ³Department of Surgery, Drexel University College of Medicine, Philadelphia, PA
Background: Preventive strategies to combat the transmission of Carbapenem-Resistant Enterobacteriaceae (CRE) include the use of active screening for CRE colonization; however, this approach is not…
2017 American Transplant Congress
TNF[part]-I After Kidney Transplantation.
B. Muth, B. Astor, D. Mandelbrot.
Department of Medicine, Division of Nephrology, University of Wisconsin, Madison, WI
Infliximab, adalimumab and etanercept are monoclonal antibodies which inhibit tumor necrosis factor alpha (TNF[part]-I) and are used in the treatment of inflammatory diseases such as…
2017 American Transplant Congress
Causes and Long-Term Consequences of Diarrhea After Kidney Transplantation.
A. Devresse,¹ F. Aulagnon,² A. Scemla,² L. Morin,² F. Lanternier,³ D. Anglicheau,² O. Lortholary,³ C. Legendre,² V. Avettand-Fenoel,⁴ J. Zuber.²
¹Nephrology Unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium; ²Kidney Transplant and Intensive Care Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; ³Infectious and Tropical Diseases Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; ⁴Virology Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France
BackgroundThe causes and effects of diarrhea on graft outcomes have been poorly investigated in a large cohort of well-phenotyped kidney transplant recipients (KT). The epidemiological…
2017 American Transplant Congress
Co-Stimulation Blockade to Minimize and Withdraw Long Term Calcineurin Inhibitors (CNI) in Simultaneous Pancreas and Kidney Transplant (SPK).
P. Stock,¹ R. Mannon,² B. Armstrong,³ D. Ikle,³ M. Robian,⁴ Y. Morrison,⁴ J. Odorico,⁵ J. Fridell,⁶ A. Mehta,⁷ K. Newell.⁷
¹UCSF, San Francisco; ²UAB, Birmingham, AL; ³Rho Inc, Chapel Hill, NC; ⁴NIH/NIAID, Bethesda, MD; ⁵UW, Madison, WI; ⁶IU, Indianapolis, IN; ⁷Emory University, Atlanta, GA
The NIH multicenter CTOT-15 trial tested the hypothesis that use of belatacept (bela) could minimize or eliminate long-term CNI use in simultaneous pancreas and kidney…