ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Infection"

  • 2018 American Transplant Congress

    Urinary Tract Infections May Be Associated with De Novo Donor-Specific Anti-Human Leucocyte Antigen Antibodies: Single-Center Study

    M. Everly,1 A. Babu,1 K. Briley,2 P. Bolin,2 S. Kendrick,3 H. Jones,3 K. McLawhorn,3 A. Maldonado,4 C. Haisch,2 D. Leeser,2 L. Rebellato.2

    1Terasaki Research Institute, Los Angeles; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Introduction: We have recently shown that immunosuppression reduction with BK virus is associated with the development of de novo donor anti-human leukocyte antigen-specific antibodies (dnDSA).…
  • 2018 American Transplant Congress

    Prospective, Multi-Center Observational Study of Cell-Mediated Immunity for Cytomegalovirus Infection in Kidney Transplant Recipients

    D. Kumar,1 P. Chin-Hong,2 L. Kayler,3 D. Wojciechowski,4 A. Limaye,5 O. Gaber,6 S. Ball,7 A. Mehta,8 T. Blanchard,9 C. Kotton.4

    1UHN, Toronto, Canada; 2UCSF, San Francisco; 3ECMC, Buffalo; 4MGH, Boston; 5UOWMC, Seattle; 6WCMC, Houston; 7UHB, Birmingham, United Kingdom; 8EmoryU, Atlanta; 9Oxford Diag, Marlborough.

    Background:T-cell-mediated immunity (CMI) is crucial for the control of CMV infection post-transplant. We evaluated a novel EliSpot assay to determine whether CMI results could predict…
  • 2018 American Transplant Congress

    Origin and Pattern of Human Polyomaviruses Replication after Kidney Transplantation: A Prospective Study

    E. Favi,1 S. Delbue,2 C. Colico,1 P. Ferrante,2 S. Villani,2 I. Perna,2 N. Mondoni,2 A. Giussani,1 L. Clementoni,1 P. Messa,3 M. Ferraresso.1

    1Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; 2Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; 3Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.

    Background. Human Polyomaviruses (HPyVs) are able to establish latent infection in the kidney of the host. Immunosuppression is recognized risk factor for HPyVs reactivation. Besides…
  • 2018 American Transplant Congress

    Clinical Outcomes of Kidney Transplant Recipients Infected with Hepatitis C Virus and Treated with Direct-Acting Antiviral Therapy

    M. Alkadi,1 E. Abuhelaiqa,1 M. Derbala,2 O. Fituri,1 J. Mahmoud,3 M. Jarman,3 M. Asim,1 A. Aziz,1 A. Nauman,1 A. Hamdi,1 Y. Medhat,2 S. Al Kaabi,2 H. Al-Malki.1

    1Medicine-Nephrology, Hamad Medical Corporation, Doha, Qatar; 2Medicine-Gastroenterology, Hamad Medical Corporation, Doha, Qatar; 3Surgery-Transplant, Hamad Medical Corporation, Doha, Qatar.

    Introduction:Hepatitis C virus (HCV) infection has negative impact on patient and graft survival in kidney transplant recipients. In the past, treatment of HCV infection post…
  • 2018 American Transplant Congress

    JC Virus-Associated Nephropathy in Renal Transplant Recipient

    G. Huang,1 M. Wang,2 X. Chen,1 S-.C. Yang,3 L. Chen.1

    1Department of Organ Transplantation, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Sun Yat-sen University, Guangzhou, China; 3Department of Pathology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

    Background: JC virus (JCV) inflection is more common than BK virus (BKV) in general population. But in kidney transplants, polyomavirus nephropathy (PVAN) is primarily caused…
  • 2018 American Transplant Congress

    Daptomycin Minimum Inhibitory Concentration (MIC) of Vancomycin Resistant Enterococcal (VRE) Blood Isolates Correlates with Allograft Failure in Orthotopic Liver Transplant (OLT) Recipients

    R. Lee,1 G. Haidar,2 J. Lewis,3 S. Arif,4 J. Hand,5 E. Holaday,6 H. Clauss,6 J. Goldman,7 A. Nellore.1

    1University of Alabama at Birmingham, Birmingham, AL; 2University of Pittsburgh Medical Center, Birmingham, AL; 3University of Virginia, Charlottesville, VA; 4Duke University, Durham, NC; 5Oschner Medical Center, New Orleans, LA; 6Department of Internal Medicine, Temple University, Philadelphia, PA; 7Temple University, Philadelphia, PA; 8Swedish Medical Center, Seattle, WA.

    Background: Enterococci are one of the leading causes of nosocomial infection in after OLT. Unfortunately, treatment options for enterococci that are resistant to first-line agents…
  • 2018 American Transplant Congress

    The Role of Pre-Emptive Antibiotic Therapy in Kidney Recipients of Donors with Urine-Only Positive Cultures

    P. Cabrera,1 A. Centeno,1 J. Revollo,1 J. Camargo.2

    1Department of Pharmacy, Jackson Memorial Hospital, Miami, FL; 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.

    Background: Donor derived infections (DDIs) can lead to significant morbidity and mortality in solid organ transplant patients. In recent years, the disparity between the need…
  • 2018 American Transplant Congress

    Burden of Infectious Complications after Upper Extremity Allotransplantation: A Matched Cohort Study

    A. Conrad,1,2,3 P. Petruzzo,4,5 J. Kanitakis,6 A. Gazarian,7 L. Badet,3,8 P. Vanhems,3,9 O. Thaunat,1,3,10 E. Morelon,1,3,10 A. Sicard.1,3

    1Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon (HCL), Lyon, France; 2Department of Infectious Diseases and Tropical Medicine, HCL, Lyon, France; 3Claude Bernard Lyon 1 University, Lyon, France; 4Department of Transplantation, HCL, Lyon, France; 5Department of Surgery, University of Cagliari, Cagliari, Italy; 6Department of Dermatology, HCL, Lyon, France; 7Clinique du Parc, Lyon, France; 8Department of Urology and Transplantation, HCL, Lyon, France; 9Infection Control and Epidemiology Unit, HCL, Lyon, France; 10INSERM U1111, International Center for Infectiology Research, Lyon, France.

    This study aimed to assess the infectious risk after upper extremity allotransplantation (UEA), a non-vital transplantation procedure requiring lifelong immunosuppression. A matched cohort study was…
  • 2018 American Transplant Congress

    HCV Ab+/NAT- Organ Donors, and the Challenges of 'Eclipse Windows': Analysis of the OPTN/UNOS Ad Hoc Disease Transmission Advisory Committee (DTAC)

    C. Wolfe, S. Tlusty, G. Vece, R. Sawyer, R. Bag, G. Berry, J. Bucio, L. Danziger-Isakov, D. Goldberg, C. Ho, D. Florescu, D. Klassen, R. La Hoz, K. Lilly, A. Mehta, M. Malinis, M. Nalesnik, N. Theodoropoulos, P. Wood, M. Michaels.

    DTAC, United Network for Organ Sharing, Richmond, VA.

    Introduction: In 2017, CDC reported new hepatitis C (HCV) cases had tripled over 5 years, mainly due to intravenous drug use (IVDU). As the proportion…
  • 2018 American Transplant Congress

    BK Viremia in Simultaneous Kidney Pancreas Recipients: Single Center Experience

    M. Alebrahim,1 R. Pelletier,1 A. Rajab,1 G. Bumgardner,1 R. Daloul,2 C. Akateh,3 K. Washburn,1 A. El-Hinnawi.1

    1Transplant Surgery, The Ohio State University Wexner Medical Center, Columbus, OH; 2Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH; 3Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.

    Introduction: The impact of BK viremia in recipients of simultaneous pancreas and kidney transplantation (SPK) is not well known. We therefore studied the incidence and…
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