ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Infection"

  • 2018 American Transplant Congress

    Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant

    S. Hamel,1 V. Kuo,2 D. Johnson,1 R. Bloom,3 D. Sawinski,3 J. Trofe-Clark.1,3

    1Pharmacy, Hosp of Univ. of Pennsylvania, Philadelphia; 2Pharmacy, Univ. of California San Francisco, San Francisco; 3Renal Division, Perelman School of Medicine, Univ. of Pennsylvania, Philadelphia.

    Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…
  • 2018 American Transplant Congress

    Intestinal Microbiome Diversity is Associated with Liver Disease Etiology and Predicts Post-Liver Transplant Mortality

    E. Verna, M. Annavajhala, M. Nenad, R. Brown, S. Sullivan, G. Korakani, M. Gidins, S. Khan, A. Gomez-Simmonds, A-.C. Uhlemann.

    Medicine, Columbia University, New York, NY.

    Background: Dysbiosis of the intestinal microbiome is common among patients with decompensated liver disease and has been associated with disease progression as well as life-threatening…
  • 2018 American Transplant Congress

    Serum Cytokines as Markers of Influenza Infection Outcomes after Transplantation

    A. L'Huillier,1 V. Ferreira,1 C. Hirzel,1 E. Cordero,2 A. Limaye,3 G. Reid,4 J. Englund,3 E. Blumberg,5 A. Humar,1 D. Kumar.1

    1UHN, Toronto, Canada; 2REIPI, Seville, Spain; 3UOWMC, Seattle; 4LUMC, Chicago; 5UPenn, Philadelphia.

    Background:Influenza infection in transplant patients can be severe but factors predictive of outcome in this setting are unclear. The aim of the study was to…
  • 2018 American Transplant Congress

    Recovery of Wild-Type Genotype after Documented Ganciclovir-Resistance in Transplant Recipients with Recurrent CMV Viremia

    J. Fose, M. Jorgenson, Z. Degrave, R. Redfield, J. Smith, D. Mandelbrot.

    University of Wisconsin Hospital, Madison; University of Wisconsin School of Medicine and Public Health, Madison.

    Purpose: Ganciclovir-resistant cytomegalovirus (GR-CMV) is serious complication after transplantation. Recurrence after primary GR-CMV infection is common, with literature defined rates of approximately 20-30%. It is…
  • 2018 American Transplant Congress

    The Impact of the Influenza Vaccine on Pediatric Kidney Transplant Outcomes

    M. Camerino,1 S. Jackson,2 S. Chinnakotla,3 P. Verghese.1

    1Department of Pediatrics, University of Minnesota, Minneapolis, MN; 2Fairview Health Services, Minneapolis, MN; 3Department of Surgery, University of Minnesota, Minneapolis, MN.

    The influenza vaccine has been associated with de novo DSA and rejection in adult kidney recipients. This risk has not been adequately assessed in pediatric…
  • 2018 American Transplant Congress

    You've Gotta Have HOPE: Seeking HIV Donors in a Large US OPO

    A. Friedman,1 S. Huprikar,2 K. Delli Carpini.1

    1LiveOnNY, NY; 2Medicine, Mount Sinai School of Medicine, NY.

    Passage of the HOPE Act in 2013 led to important workflow changes within a large US organ procurement organization (OPO). The initial triage process for…
  • 2018 American Transplant Congress

    A National Survey of Valganciclovir Dosing Strategies in Pediatric Solid Organ Transplant Recipients

    S. Shaikh, N. Panek, J. Park.

    MedStar Georgetown University Hospital, Washington DC; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago; Michigan Medicine, Ann Arbor.

    Objective: The FDA-approved pediatric indication of valganciclovir (VGCV) is limited to cytomegalovirus (CMV) prophylaxis in heart and kidney transplants. The recommended regimen is a daily…
  • 2018 American Transplant Congress

    Oral Vancomycin Monotherapy versus Combination Therapy in Solid Organ Transplant Recipients with Uncomplicated Clostridium difficile Infection: A Retrospective Cohort Study

    G. Korayem,1,2,4 K. Eljaaly,2,3 K. Matthias,2,4 T. Zangeneh.4,5

    1Department of Pharmaceutical Practices, Princess Nourah Bint Abdulrahman University, Riyadh, NA, Saudi Arabia; 2Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ; 3Department of Clinical Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 4Banner - University Medical Center Tucson, Tucson, AZ; 5Division of Infectious Diseases, Department of Medicine, University of Arizona, Tucson, AZ.

    Introduction:Solid organ transplant (SOT) recipients are at high risk of Clostridium difficile infection (CDI) and CDI recurrence. A combination of metronidazole and oral vancomycin is…
  • 2018 American Transplant Congress

    Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis

    M. Fung,1 J. Greenland,2,3 S. Hays,2 J. Singer,2 J. Golden,2 P. Chin-Hong.1

    1Infectious Diseases, University of California San Francisco, San Francisco, CA; 2Pulmonary and Critical Care, University of California San Francisco, San Francisco, CA.

    Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…
  • 2018 American Transplant Congress

    Humoral Immune Response to Seasonal Influenza Infection in Transplant Recipients

    C. Hirzel,1 V. Ferreira,1 A. L'Huillier,1 K. Hoschler,2 E. Cordero,3 G. Reid,4 J. Englund,5 A. Limaye,6 A. Humar,1 D. Kumar.1

    1UHN, Toronto, Canada; 2Public Health England, London, United Kingdom; 3REIPI, Sevilla, Spain; 4LUMC, Chicago; 5SCH, Seattle; 6UOWMC, Seattle.

    Background: Little is known about the serologic response to natural influenza infection in transplant recipients. We describe the hemagglutinin antibody response to influenza A/H1N1 infection…
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