2018 American Transplant Congress
Alveolar Macrophages Derived from MCMV Latently Infected Donors Drives the Viral Reactivation and Dissemination Following the Orthotopic Left Lung Transplantation in Mice
Background: The incidence of cytomegalovirus (CMV) disease is higher in lung transplants, than in other SOT recipients, especially in high-risk D+/R- recipients. Using a murine…2018 American Transplant Congress
The Etiologies and Impact of Hospitalization in Older Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
Older kidney transplant recipients (KTR) face challenges of post-transplant complications related to frailty and comorbidities. They are particularly vulnerable to infectious complications. This study elucidates…2018 American Transplant Congress
Cryptococcal Infections in Kidney Transplant Recipients. A Single Center Experience
Cryptococcal infections are infrequent but a cause of morbidity & mortality in transplant (T) recipients. Best treatment and the need for secondary prophylaxis are still…2018 American Transplant Congress
mTOR Inhibitor Based Immunosuppression Regimens Are Not Associated with Lower Risk for BK Infection
Introduction: BK virus continues to be a significant post-transplant complication with increasing incidence in the current era of potent immunosuppression. Mammalian target of rapamycin inhibitors…2018 American Transplant Congress
Identifying Differences in Antimicrobial Resistance with a Liver Transplant Antibiogram
Methodist Dallas Medical Center, Dallas.
Regulatory requirements for antimicrobial stewardship pose a unique challenge in special populations including transplant recipients. Infection following liver transplant can adversely impact patient outcomes. Moreover,…2018 American Transplant Congress
Having Your Cake and Eating It Too: An Aggressive Protocol for DSA Treatment Does Not Doom Patients to High Infectious Risk
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
Introduction: Antibody mediated rejection (AMR) is one of the most difficult complications to treat in kidney transplantation. We previously reported on our experience with an…2018 American Transplant Congress
Significant Anti-CMV/BKV Effect of a Modern Everolimus-Based Regimen Comparted to a Standard Tacrolimus-MPA Regimen in De Novo Kidney Transplant Recipients: ATHENA 12 Months Data on Infections
1Athena Study Group, Germany; 2Athena Study Group, France; 3Novartis, Pharma, Germany.
The ATHENA trial was designed to compare everolimus [EVR] in combination with tacrolimus [TAC] or cyclosporine A [CyA] vs. a standard regimen of mycophenolic acid…2018 American Transplant Congress
Frailty is Predictive of Early Post-Transplant Infection in Older Renal Transplant Recipients
Background: Frailty is predictive of postoperative morbidity, including infections in older surgical patients. It is not known if frailty is associated with post-operative infections in…2018 American Transplant Congress
Early Infectious Outcomes of Older Adults Undergoing Kidney Transplantation (KT). A Case Control Study
Study Purpose: Our aim was to investigate if among older KT recipient, the types of infections, number of rejections, graft and patient survival in the…2018 American Transplant Congress
Prediction of BK Viremia by Urine BK Viral Load in Renal Transplant Patients: BK Viral Load Results in Paired Urine and Plasma Samples
BK virus (BKV) associated nephropathy (BKVAN) affects up to 10% of renal transplant recipients, causing graft failure without intervention; a presumptive BKVAN diagnosis is made…
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