ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Infection"

  • 2019 American Transplant Congress

    Thymoglobulin Efficacy: The Role of Dosing on Viral Infection and Rejection in Pancreas Transplantation

    H. Sarumi, B. Johnson, S. Jackson, S. Hogan, J. Fisher, S. Riad, R. Kandaswamy, T. Pruett

    Transplant Surgery, University of Minnesota Medical Center, Minneapolis, MN

    *Purpose: While T-cell depletion therapy is standard practice for induction in pancreas transplantation, little data exists to help determine dosing and its impact on efficacy…
  • 2019 American Transplant Congress

    Evaluation of Influenza Virus Antibody Response in Naturally Infected and Vaccinated Transplant Recipients by Protein Microarray

    C. Hirzel, A. Chruscinski, V. H. Ferreira, A. G. L'Huillier, A. Humar, D. Kumar

    University Health Network, Toronto, ON, Canada

    *Purpose: Influenza A virus (IAV) infection is known to be an important cause of morbidity in solid organ transplant (SOT) recipients. The objective of our…
  • 2019 American Transplant Congress

    Antithymocyte Globulin is Associated with Mature T Cell Phenotypes and Decreased Risk of Non-EBV Infections in Transplanted Children

    B. I. Shaw1, L. Stempora1, C. Chan1, R. B. Ettenger2, P. C. Grimm3, H. Lee1, E. F. Reed2, M. M. Sarwal4, B. L. Warshaw5, C. Zhao1, O. M. Martinez3, A. D. Kirk1, E. T. Chambers1

    1Pediatrics/Surgery, Duke University, Durham, NC, 2Pediatrics, University of California, Los Angeles, Los Angeles, CA, 3Pediatrics/Surgery, Stanford University, Palo Alto, CA, 4Pediatrics/Surgery, University of California, San Francisco, San Francisco, CA, 5Pediatrics, Emory University, Atlanta, GA

    *Purpose: Depletional induction therapies are known to reduce the rate of acute rejection; yet data from the US Renal Data System have shown that use…
  • 2019 American Transplant Congress

    Experience With Letermovir Use For The Management Of Cytomegalovirus In Solid Organ Transplant Recipients

    J. L. Orejas1, F. M. Marty1, A. M. McDonnell2, M. P. Cheng1, E. Arbona-Haddad1, S. P. Hammond1, S. Koo1

    1Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, 2Department of Pharmacy, Brigham and Women's Hospital, Boston, MA

    *Purpose: Letermovir is a new antiviral recently approved for cytomegalovirus (CMV) prophylaxis in CMV-seropositive hematopoietic-cell transplant recipients. Its off-label use in solid organ transplant (SOT)…
  • 2019 American Transplant Congress

    Infective Complications after Renal Transplantation – A Single Centre Experience Comparing Alemtuzumab to Basiliximab Induction

    R. Czajka, M. Welberry Smith, M. Gittus, E. Lindley, M. Vernon

    Renal Medicine, St James' University Hospital, Leeds, United Kingdom

    *Purpose: Our centre predominantly uses alemtuzumab as induction immunosuppression for renal transplantation. We examined infective complications after renal transplantation, comparing different induction, and maintenance, immunosuppression…
  • 2019 American Transplant Congress

    Evaluation of Rabbit Antithymocyte Globulin (rATG) Dosing and Incidence of Opportunistic Viral Infections in Kidney Transplant Recipients Using Tacrolimus (TAC), Mycophenolate (MPA) and Steroid Free Maintenance Immunosuppression

    L. Von Stein, A. Leino, R. Amer, T. Pesavento, H. Winters

    The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: There is limited literature evaluating rATG dosing and incidence of infection with TAC/MPA and early steroid withdrawal. This study evaluates rATG dosing and overall…
  • 2019 American Transplant Congress

    EBV Viremia and Development of EBV Specific Cytotoxic T-cells in Pediatric Renal Transplant Recipients

    H. Pizzo, D. Puliyanda, B. Shin, M. Toyoda, S. Jordan

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: The use of lymphocyte depleting agents (LDA) for induction immunosuppression among renal transplant (tx) recipients raises concern for the increased susceptibility to viral infections,…
  • 2019 American Transplant Congress

    Biomarkers in Multivisceral and Intestinal Transplantation

    D. A. Cheung1, J. Garcia1, T. Beduschi2, A. H. Langshaw1, K. L. Arheart3, I. A. Gonzalez4

    1Pediatric Gastroenterology, University of Miami, Miami, FL, 2Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, 3Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, 4Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL

    *Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…
  • 2018 American Transplant Congress

    Prospective, Multi-Center Observational Study of Cell-Mediated Immunity for Cytomegalovirus Infection in Kidney Transplant Recipients

    D. Kumar,1 P. Chin-Hong,2 L. Kayler,3 D. Wojciechowski,4 A. Limaye,5 O. Gaber,6 S. Ball,7 A. Mehta,8 T. Blanchard,9 C. Kotton.4

    1UHN, Toronto, Canada; 2UCSF, San Francisco; 3ECMC, Buffalo; 4MGH, Boston; 5UOWMC, Seattle; 6WCMC, Houston; 7UHB, Birmingham, United Kingdom; 8EmoryU, Atlanta; 9Oxford Diag, Marlborough.

    Background:T-cell-mediated immunity (CMI) is crucial for the control of CMV infection post-transplant. We evaluated a novel EliSpot assay to determine whether CMI results could predict…
  • 2018 American Transplant Congress

    Origin and Pattern of Human Polyomaviruses Replication after Kidney Transplantation: A Prospective Study

    E. Favi,1 S. Delbue,2 C. Colico,1 P. Ferrante,2 S. Villani,2 I. Perna,2 N. Mondoni,2 A. Giussani,1 L. Clementoni,1 P. Messa,3 M. Ferraresso.1

    1Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; 2Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; 3Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.

    Background. Human Polyomaviruses (HPyVs) are able to establish latent infection in the kidney of the host. Immunosuppression is recognized risk factor for HPyVs reactivation. Besides…
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