Articles tagged "Infection"

2019 American Transplant Congress
Routine Molecular Clostridioides difficile Screening and Overtreatment in Solid Organ Transplant Recipients
M. E. Newman¹, C. Oehler¹, M. Enriquez¹, E. Landon¹, C. T. Nguyen², N. N. Pettit², J. P. Ridgway¹, J. Pisano¹
¹Section of Infectious Disease, University of Chicago Medicine, Chicago, IL, ²Department of Pharmacy, University of Chicago Medicine, Chicago, IL
*Purpose: The objective of this analysis is to determine how frequently positive Clostridioides difficile (CD) screening tests, potentially identifying up to 20% of inpatients with…
2019 American Transplant Congress
Risk Factors for 1-5 Year Major Infection Events (MIE) after Kidney Transplant (KTx) Including First-Year Immunosuppression (IS) Data: An Analysis of the Choosing Immune Suppression in Renal Transplantation by Efficacy and Morbidity (CISTEM) Study
V. Dharnidharka¹, D. Axelrod², Z. Zhang³, M. Schnitzler³, K. Lentine³, B. Kasiske⁴
¹Washington Univ, St. Louis, MO, ²Univ of Iowa, Iowa City, IA, ³Saint Louis Univ, St. Louis, MO, ⁴SRTR, Minneapolis, MN
*Purpose: From our CISTEM study of linked national registries, we reported that older recipient age, female sex, diabetic kidney failure, non-standard-criteria organs, and mTORi-based IS…
2019 American Transplant Congress
Phylogenetic Analysis of the Epstein Barr Virus Nuclear Antigen-1 and Associated Correlates among Canadian Transplant Patients
M. Abdulnoor¹, S. Isabel¹, T. Paton¹, N. Khodai-Booran¹, T. Schechter¹, P. Birk², T. Blydt-Hansen³, B. Foster⁴, S. Mital¹, V. Phan⁵, S. Urschel⁶, G. Casallo¹, T. Papaz¹, L. Hamiwka⁷, S. Min¹, U. Allen¹
¹University of Toronto, Toronto, ON, Canada, ²University of Manitoba, Winnipeg, MB, Canada, ³University of British Columbia, Vancouver, BC, Canada, ⁴McGill University, Montreal, QC, Canada, ⁵University of Montreal, Montreal, QC, Canada, ⁶University of Alberta, Edmonton, AB, Canada, ⁷University of Calgary, Calgary, AB, Canada
*Purpose: The effect of the genetic diversity of the Epstein-Barr virus (EBV) on clinical outcomes in the transplant setting is important to study. We examined…
2019 American Transplant Congress
Rejection, Infectious, and Renal Outcomes with Perioperative Desensitization in Orthotopic Heart Transplant Recipients
M. Plazak, B. Reed, S. Hammad, S. Gale, V. Ton, D. Kaczorowski, T. Trobiano, B. Ravichandran
University of Maryland Medical Center, Baltimore, MD
*Purpose: Pre-transplant allosensitization remains a significant barrier to organ allocation and a paucity of evidence exists to demonstrate the efficacy and safety of perioperative desensitization…
2019 American Transplant Congress
Treatment of Latent Tuberculosis Infection with Short-Course Regimens in Potential Living Kidney Donors
J. Simkins, C. Donato-Santana, M. I. Morris, L. M. Abbo, J. F. Camargo, S. Anjan, Y. Natori, G. Guerra
Medicine, University of Miami, Miami, FL
*Purpose: Treatment data for latent tuberculosis infection (LTBI) among potential living kidney donors is scarce. The use of 12-week isoniazid (INH) and rifapentine (RPT) in…
2019 American Transplant Congress
Oral Ribavirin Therapy for Respiratory Syncytial Virus (RSV) in Lung Transplant Recipients: The Impact of Policy Implementation on Cost and Appropriate Use
B. Berak, N. Sulejmani, A. Jantz, T. Larson, S. Davis, B. Summers
Henry Ford Hospital, Detroit, MI
*Purpose: RSV is a leading cause of viral infections in lung transplant recipients and is associated with significant morbidity and mortality. While the role of…
2019 American Transplant Congress
Contemporary US Prevalence and Outcomes of Pneumocystis jirovecii Pneumonia and Toxoplasmosis in Pediatric Solid Organ and Hematopoietic Cell Transplantation Recipients
M. I. Ardura¹, J. Stanek², B. Hanisch³, B. Hanisch⁴, K. Sprott⁵, H. Rangarajan⁶
¹Pediatrics, Infectious Diseases & Host Defense, Nationwide Children's Hospital & The Ohio State University, Columbus, OH, ²Pediatrics, Biostatistics, Nationwide Children's Hospital, Columbus, OH, ³Pediatrics, Infectious Diseases, Children's National Health System, Washington, DC, ⁴Pediatrics, Infectious Diseases, Children's National Health System & The George Washington University, Washington, DC, DC, ⁵Pediatrics, Pharmacy, Medical University of South Carolina, Charleston, SC, ⁶Pediatrics, Hematology/Oncology/HCT, Nationwide Children's Hospital & The Ohio State University, Columbus, OH
*Purpose: We sought to evaluate the contemporary prevalence and outcomes of Pneumocystis jirovecii pneumonia (PCP) and toxoplasmosis among pediatric transplantation recipients in the US in…
2019 American Transplant Congress
The Impact of Antibiotic Therapy on Clinical Outcomes in Kidney Transplant Recipients with Asymptomatic Bacteriuria
J. Gabriel¹, S. Shaikh², J. Park¹, S. Tischer¹, D. Kaul¹, T. Patel¹
¹Michigan Medicine, Ann Arbor, MI, ²MedStar Georgetown University Hospital, Washington, DC
*Purpose: Asymptomatic bacteriuria (ASB) occurs in nearly 50% of kidney transplant recipients (KTRs) in the first year post-transplant. Data evaluating the risk of untreated ASB…
2019 American Transplant Congress
Comparison of Proton Pump Inhibitors versus Histamine-2-Receptor Antagonists on Clostridium difficile Rates in Liver Transplant Recipients
S. Wiehe, K. Roach, A. Qamar
Lahey Hospital and Medical Center, Burlington, MA
*Purpose: To determine if there is a difference in 90 day Clostridium difficile infection (CDI) rates before and after the stress ulcer prophylaxis (SUP) protocol…
2019 American Transplant Congress
Utility of Gallium-67 Single Photon Emission Computed Tomography in the Evaluation of Left Ventricular Assist Device Infections
F. Parkar¹, A. Tlamsa², J. Nistico², V. A. Muggia², G. Y. Minamoto², U. Jorde³, D. J. Goldstein³, R. Moadel¹, Y. A. Puius²
¹Division of Nuclear Medicine, Montefiore Medical Center, Bronx, NY, ²Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, ³Department of Cardiothoracic and Vascular Surgery, Montefiore Medical Center, Bronx, NY
*Purpose: We routinely use gallium-67 single photon emission computed tomography (67Ga-SPECT-CT) to determine the presence and extent of left ventricular assist device (LVAD) infections. The…