Articles tagged "Infection"

2019 American Transplant Congress
Burden of Respiratory Syncytial Disease among Hospitalized Immunocompromised Adults
H. Nam, M. Ison
Northwestern University Comprehensive Transplant Center, Chicago, IL
*Purpose: Respiratory syncytial virus (RSV) is associated with significant mortality amongst hematopoietic stem cell transplant (HSCT) and lung transplant recipients. Although RSV is responsible for…
2019 American Transplant Congress
Quantifying Differential Infection Risks in HLA- and/or ABO- Incompatible Kidney Transplant Recipients
R. Avery¹, R. Montgomery², J. Motter¹, A. Massie¹, E. Kraus¹, K. Marr¹, B. Lonze², N. Alachkar¹, K. Jackson¹, M. Holechek¹, D. Ostrander¹, N. Desai¹, M. Waldram¹, S. Shoham¹, S. Mehta¹, J. Hiller¹, J. Langlee¹, S. Young¹, D. Segev¹, J. Garonzik Wang¹
¹Johns Hopkins, Baltimore, MD, ²New York University, New York, NY
*Purpose: Desensitization has enabled kidney transplantation across HLA-and/or ABO barriers and has conferred survival benefit to patients who lack compatible living donors (CLDKT). However, due…
2019 American Transplant Congress
Donor Derived Strongyloidiasis, a Preventable Event
R. M. La Hoz¹, G. Vece², L. Danziger-Isakov¹, D. Florescu¹, M. Malinis¹, K. Lilly¹, L. Strasfeld¹, R. P. Wood¹, S. Tlusty², C. R. Wolfe¹, M. G. Michaels¹
¹DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: In the US, deceased donor screening for Strongyloides started in 2010. By 2013 10% of the OPOs had implemented screening practices. Recipients of sero-positive…
2019 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) May Aid in the Diagnosis of BK Virus Nephropathy
D. Brennan¹, J. Bromberg², J. Yee³, S. Dholakia³, M. Haas⁴
¹Johns Hopkins, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD, ³CareDx, Brisbane, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Between 10% and 30% of renal transplant recipients (KTR) develop BK viremia; with 1-10% of KTR developing BK virus associated nephropathy (BKVAN), accounting for…
2019 American Transplant Congress
Multidisciplinary Transplant UTI Service; Challenging the Stalemate
J. J. Chong, A. Adiki, D. Ness, J. Olsburgh, R. H. Zakri
Guy's Hospital, London, United Kingdom
*Purpose: Symptomatic UTIs (urinary tract infections) cause a significantly detrimental effect on long term graft function. Immunosuppression coupled with underlying renal or urological abnormality makes…
2019 American Transplant Congress
Polyomavirus Genotypes In Renal Transplant Recipients In The United States
N. Khoury¹, C. Thongprayoon², N. Leeaphorn³, J. Bruminhent⁴, W. Cheungpasitporn⁵
¹Henry Ford Transplant Institute, Detroit, MI, ²Mayo Clinic, Rochester, MN, ³University of Missouri, Kansas, MO, ⁴Mahidol University, Bangkok, Thailand, ⁵University of Mississippi, Jackson, MS
*Purpose: BK Polyomavirus (BKV) subtypes and subgroups present uneven geographical distribution, suggesting a potential relationship with ethnicity. In the United States where there is a…
2019 American Transplant Congress
Single-center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis Carinii Pneumonia in Patients with Poor Renal Function
Y. Fu, J. Pan, Z. Shen
Kidney-Pancreas Transplant Department., Tianjin First Central Hospital, Tianjin, China
*Purpose: Pneumocystis carinii pneumonia (PcP) is a potentially life-threatening complication in renal transplant recipients. Although the use of trimethoprim-sulfamethoxazole (TMP-SMX) chemoprophylaxis after kidney transplantation is…
2019 American Transplant Congress
A Single-Center Experience with a 6-Month Regimen of Pneumocystis jiroveci Pneumonia Prophylaxis in HIV-Positive Kidney Transplant Recipients
C. Mejia¹, G. Malat², D. H. Lee³, S. Epstein¹, M. Harhay³, L. Levin Mizrahi³, K. Ranganna³
¹Drexel University, Philadelphia, PA, ²Hahnemann University Hospital, Philadelphia, PA, ³Medicine, Drexel University, Philadelphia, PA
*Purpose: Pneumocystis jiroveci pneumonia (PJP) prophylaxis is recommended for all kidney transplant recipients (KTR) for after transplant. HIV-positive KTRs represent a unique subset, and there…
2019 American Transplant Congress
Evolution of HHV6- and CMV-Specific T Cell Functional Responses and Immune Cell Populations after Kidney Transplant
A. Gil¹, M. Co², M. Calvo-Calle¹, J. Cruz¹, L. Stern¹, L. Gibson²
¹Pathology, University of Massachusetts Medical School, Worcester, MA, ²Medicine, University of Massachusetts Medical School, Worcester, MA
*Purpose: Human herpesvirus (HHV)-6 reactivation after solid organ or hematopoietic stem cell transplant has been associated with complications such as graft rejection and all-cause mortality.…
2019 American Transplant Congress
Profile of Invasive Fungal Disease after Kidney Transplantation in a Single Brazilian Center
S. C. Miranda, G. M. Pereira Junior, C. A. Felipe, A. S. Alvarenga, P. A. Macedo Souza, C. Ribeiro, S. C. Cantini
Nephrology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
*Purpose: This study sought to describe the epidemiology of Invasive fungal disease at a brazilian kidney transplant center.*Methods: We retrospectively evaluated the diagnoses of invasive…