Articles tagged "Infection"

2019 American Transplant Congress
Infectious Complications in 71 Heart Transplant Recipients at King Chulalongkorn Memorial Hospital, Thailand
N. Sangpornsuk¹, J. Wanichwatphibun², A. Ariyachaipanich³, P. Ongcharit⁴, K. Jutivorakool⁵, J. Vanichanan⁵
¹Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, ²Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, ³Excellent Center for Organ Transplantation, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, ⁴Cardiothoracic Surgery Unit, Department of Surgery, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, ⁵Division of Infectious Diseases, Department of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand
*Purpose: Infections have been known as one of the major complication associated with morbidity and mortality especially in the first year following orthotropic heart transplantation…
2019 American Transplant Congress
The Association Of Frailty With Risk Of Cytomegalovirus And BK Infection
J. Norman¹, A. Gupta², A. Naik³, D. Cibrik², S. Norman³
¹Internal Medicine, Univ of Michigan Medical Ctr, Ann Arbor, MI, ²Internal Medicine/Nephrology, Kansas University Medical Center, Kansas City, KS, ³Internal Medicine/Nephrology, Univ of Michigan Medical Ctr, Ann Arbor, MI
*Purpose: Opportunistic infections are responsible for significant morbidity and mortality post-kidney transplant (KT). Recently, medical frailty has been recognized to increase the risk of death…
2019 American Transplant Congress
The Utility of Donor and Recipient BK Virus Antibody Testing Prior to Renal Transplantation in Risk Assessment for Developing BK Viremia
N. Donmez, S. I. Al-Akash
Driscoll Children's Hospital, Corpus Christi, TX
*Purpose: The correlation between donor (DON) and recipient (REC) BKV antibody (AB) titers and BK viremia in renal transplant (RTx) has not been well-studied in…
2019 American Transplant Congress
Thymoglobulin Efficacy: The Role of Dosing on Viral Infection and Rejection in Pancreas Transplantation
H. Sarumi, B. Johnson, S. Jackson, S. Hogan, J. Fisher, S. Riad, R. Kandaswamy, T. Pruett
Transplant Surgery, University of Minnesota Medical Center, Minneapolis, MN
*Purpose: While T-cell depletion therapy is standard practice for induction in pancreas transplantation, little data exists to help determine dosing and its impact on efficacy…
2019 American Transplant Congress
Evaluation of Influenza Virus Antibody Response in Naturally Infected and Vaccinated Transplant Recipients by Protein Microarray
C. Hirzel, A. Chruscinski, V. H. Ferreira, A. G. L'Huillier, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: Influenza A virus (IAV) infection is known to be an important cause of morbidity in solid organ transplant (SOT) recipients. The objective of our…
2019 American Transplant Congress
Antithymocyte Globulin is Associated with Mature T Cell Phenotypes and Decreased Risk of Non-EBV Infections in Transplanted Children
B. I. Shaw¹, L. Stempora¹, C. Chan¹, R. B. Ettenger², P. C. Grimm³, H. Lee¹, E. F. Reed², M. M. Sarwal⁴, B. L. Warshaw⁵, C. Zhao¹, O. M. Martinez³, A. D. Kirk¹, E. T. Chambers¹
¹Pediatrics/Surgery, Duke University, Durham, NC, ²Pediatrics, University of California, Los Angeles, Los Angeles, CA, ³Pediatrics/Surgery, Stanford University, Palo Alto, CA, ⁴Pediatrics/Surgery, University of California, San Francisco, San Francisco, CA, ⁵Pediatrics, Emory University, Atlanta, GA
*Purpose: Depletional induction therapies are known to reduce the rate of acute rejection; yet data from the US Renal Data System have shown that use…
2019 American Transplant Congress
Experience With Letermovir Use For The Management Of Cytomegalovirus In Solid Organ Transplant Recipients
J. L. Orejas¹, F. M. Marty¹, A. M. McDonnell², M. P. Cheng¹, E. Arbona-Haddad¹, S. P. Hammond¹, S. Koo¹
¹Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA, ²Department of Pharmacy, Brigham and Women's Hospital, Boston, MA
*Purpose: Letermovir is a new antiviral recently approved for cytomegalovirus (CMV) prophylaxis in CMV-seropositive hematopoietic-cell transplant recipients. Its off-label use in solid organ transplant (SOT)…
2019 American Transplant Congress
Infective Complications after Renal Transplantation – A Single Centre Experience Comparing Alemtuzumab to Basiliximab Induction
R. Czajka, M. Welberry Smith, M. Gittus, E. Lindley, M. Vernon
Renal Medicine, St James' University Hospital, Leeds, United Kingdom
*Purpose: Our centre predominantly uses alemtuzumab as induction immunosuppression for renal transplantation. We examined infective complications after renal transplantation, comparing different induction, and maintenance, immunosuppression…
2019 American Transplant Congress
Evaluation of Rabbit Antithymocyte Globulin (rATG) Dosing and Incidence of Opportunistic Viral Infections in Kidney Transplant Recipients Using Tacrolimus (TAC), Mycophenolate (MPA) and Steroid Free Maintenance Immunosuppression
L. Von Stein, A. Leino, R. Amer, T. Pesavento, H. Winters
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: There is limited literature evaluating rATG dosing and incidence of infection with TAC/MPA and early steroid withdrawal. This study evaluates rATG dosing and overall…
2019 American Transplant Congress
EBV Viremia and Development of EBV Specific Cytotoxic T-cells in Pediatric Renal Transplant Recipients
H. Pizzo, D. Puliyanda, B. Shin, M. Toyoda, S. Jordan
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: The use of lymphocyte depleting agents (LDA) for induction immunosuppression among renal transplant (tx) recipients raises concern for the increased susceptibility to viral infections,…