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Articles tagged "Infection"

  • 2020 American Transplant Congress

    Outpatient Treatment of Paramyxovirus with Oral Ribavirin is Safe and Effective in Lung Transplant Recipients

    A. W. Rogers1, B. J. Pierce1, C. Pham1, J. T. Swan1, H. J. Huang2

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: Respiratory paramyxovirus infections present an increased risk to lung transplant recipients (LTRs), including rapid decline in graft function and immunologic sequelae such as rejection…
  • 2020 American Transplant Congress

    Effectiveness and Tolerability of Cidofovir for the Management of BK Viremia in Kidney Transplant Recipients

    M. Thornberg1, J. Hedvat1, N. Lange1, C. Brennan2, D. Salerno1, D. Tsapepas2

    1NewYork-Presbyterian Hospital, Department of Pharmacy, New York, NY, 2Columbia Irving University Medical Center, Department of Transplant Surgery, New York, NY

    *Purpose: BK viremia (BKV) is a common complication after kidney transplantation (KT) that often leads to graft dysfunction and loss. Without consensus management guidelines and…
  • 2020 American Transplant Congress

    Bile Microbiology and Antibiotic Susceptibility in Liver Transplant Recipients versus Non-Transplant Population

    S. Suh, Y. Choi

    Surgery, Chung-Ang University Hospital, Seoul, Korea, Republic of

    *Purpose: The signs and symptoms of biliary infection in liver transplantation (LT) recipients are frequently subtle because of immunosuppression, thereby delaying its diagnosis and increasing…
  • 2020 American Transplant Congress

    Experience with a BKV-Specific, Neutralizing Monoclonal Antibody (MAU868) for Treatment of Severe BK Virus Nephropathy (BKVN) after Kidney Transplant (FDA EIND #139112)

    S. C. Jordan1, S. J. Kovacs2, J. R. Abend3, N. Ammerman1, M. Toyoda1, C. C. Nast1, E. Huang1, R. Najjar1, S. Sethi1, A. Peng1, K. Lim1, M. R. Hodges4, A. Vo1

    1Cedars Sinai Medical Ctr, Los Angeles, CA, 2Novartis Institutes for BioMedical Research, East Hanover, NJ, 3Novartis Institutes for BioMedical Research, Emeryville, CA, 4Amplyx Pharmaceuticals, San Diego, CA

    *Purpose: BK viral reactivation leading to nephropathy and allograft loss in kidney transplant recipients remains a significant challenge. No effective BKV-therapies are currently available. Management…
  • 2020 American Transplant Congress

    Testing Deceased Organ Donors for Infections: An Organ Procurement Organization (OPO) Survey

    N. M. Theodoropoulos1, P. Chin-Hong2, M. Greenwald3, M. G. Ison4

    1University of Massachusetts Medical School, Worcester, MA, 2UCSF, San Francisco, CA, 3Uniformed Services University School of Medicine, Bethesda, MD, 4Northwestern University, Chicago, IL

    *Purpose: We surveyed the 58 U.S. OPOs to update our knowledge about the current methods of infectious disease testing in deceased organ donors.*Methods: An IRB…
  • 2020 American Transplant Congress

    Risk of Tuberculosis in Kidney Transplantation Recipients Compared to Dialysis Patients or General Population: A Nationwide Cohort Study with Matched Controls

    S. Park1, J. Kim2, M. Yu3, J. Lee2, K. Han4, S. Park1, Y. Kim2, D. Kim2, Y. Kim2, H. Lee2

    1Armed Forces Capital Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of, 3Hanyang Guri Hospital, Gyeonggi-do, Korea, Republic of, 4Catholic University, College of Medicine, Seoul, Korea, Republic of

    *Purpose: Risk of Mycobacterium tuberculosis (TB) infection has been reported to be increased in kidney transplant recipients. However, a nationwide cohort study from an Asian…
  • 2020 American Transplant Congress

    Rare Case of Donor Transmission of Hepatitis a Virus in Two Kidney Transplant Recipients

    A. Kumar, S. Rao, A. Nishio Lucar, C. Argo, M. Poulter, A. Doyle

    University of Virginia, Charlottesville, VA

    *Purpose: Infectious transmission via solid organ transplant (SOT) remains an inherent risk of transplantation despite measures to mitigate the risk. We report a rare case…
  • 2020 American Transplant Congress

    Monitoring Recipients of Public Health Service (PHS) Increased Risk Donors Using an Electronic Medical Record-Based System

    M. Malinis1, B. Nuesse2, S. Carter2, S. Emre1, R. Formica1, S. Kulkarni1, D. Mulligan1, M. Schilsky1, M. M. Azar1

    1Yale School of Medicine, New Haven, CT, 2Yale New Haven Health, New Haven, CT

    *Purpose: In 2014, the Organ Procurement and Transplantation Network (OPTN) policy was updated, mandating transplant centers to implement a post-transplant screening protocol for transmissible diseases.…
  • 2020 American Transplant Congress

    Risk Factors for Bacterial or Candidal Donor-Derived Infections among Solid Organ Transplant Recipients

    J. A. Anesi1, E. Lautenbach1, J. H. Han2, D. H. Lee3, H. Clauss4, R. Hasz5, E. Molnar4, D. Alimenti1, A. R. Motzer4, S. West5, W. B. Bilker1, P. Tolomeo1, E. A. Blumberg1, T. Prevention Epicenters Program6

    1University of Pennsylvania, Philadelphia, PA, 2GlaxoSmithKline, Rockville, MD, 3Drexel University, Philadelphia, PA, 4Temple University, Philadelphia, PA, 5Gift of Life Donor Program, Philadelphia, PA, 6Centers for Disease Control and Prevention, Atlanta, GA

    *Purpose: Donor-derived infections (DDIs) among solid organ transplant recipients (SOTR) are often associated with significant morbidity and mortality, although the predisposing factors for DDIs remain…
  • 2020 American Transplant Congress

    The Safety and Effectiveness and of Isoniazid Empirical Prophylaxis Compared to Screening Based Prophylaxis Post Lung Transplantation

    G. B. Korayem1, R. S. Almaghrabi2, N. I. AlSuhaibani1, G. S. AlSwailem1, M. A. AlShammari1, D. A. Aleissa3

    1Pharmacy Practice Department, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, 2Section of Infectious Diseases, Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, 3Transplant Clinical Pharmacist, Pharmaceutical Care Division, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: Even though guidelines recommend using isoniazid (INH) for TB prophylaxis depending on donors and recipients’ screening tests, previous studies supported its use in all…
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