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Articles tagged "Infection"

  • 2022 American Transplant Congress

    Real-Time Biometric Monitoring Using Wearable Devices for Pediatric Heart Transplant Rejection and Infection Surveillance

    D. Gandla1, J. B. Edelson2, E. Mukhtar1, J. Callanan1, H. Lad1, H. Gao1, J. Cornetta1, B. Keating1

    1Department of Surgery, Perelman School of Medicine, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Monitoring for acute rejection (AR) after orthotopic heart transplantation (OHTx) is primarily achieved by evaluating histological endomyocardial biopsies (EMBx). However, this procedure is limited…
  • 2022 American Transplant Congress

    Lung Transplantation Outcomes in Recipients Living with HIV in the United States

    J. M. Czeresnia1, S. Madan2, M. M. Abbasi3, V. Hemmige1

    1Department of Medicine - Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, 2Department of Medicine - Division of Cardiology, Montefiore Medical Center, Bronx, NY, 3Department of Surgery - Division of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY

    *Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…
  • 2022 American Transplant Congress

    Data-Driven Clustering Distinguishes Infection from Rejection During Hospital Admissions Following Pediatric Lung Transplantation

    C. D. Britto1, D. Boyer2, G. Visner3, G. Priebe4, L. Midyat3

    1Department of Pediatrics, Boston Children's Hospital, Boston, MA, 2Division of Pulmonary Medicine, Nationwide Children's Hospital, Ohio, MA, 3Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, 4Department of Anesthesiology, Critical Care and Pain Medicine, Division of Infectious Disease, Boston Children's Hospital, Boston, MA

    *Purpose: When lung transplantation patients are admitted with respiratory symptoms, distinguishing between episodes of infection and rejection is central to determining immunosuppressive management.*Methods: Data comprising…
  • 2022 American Transplant Congress

    Implementation of Infectious Disease Surveillance in Recently Deceased Human Xenograft Study

    S. J. Cawthon, E. P. Weldon, N. S. Lawson, B. E. Lonze, R. A. Montgomery, S. A. Mehta

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Xenotransplantation is a promising solution for the ongoing organ shortage but has been slow to develop because of both immunological challenges and potential risk…
  • 2022 American Transplant Congress

    The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness

    C. K. Ching1, Y. R. Nobel2, M. R. Pereira3, E. C. Verna4

    1Department of Medicine, Columbia University Medical Center, New York, NY, 2Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, 3Division of Infectious Diseases, Columbia University Medical Center, New York, NY, 4Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY

    *Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…
  • 2022 American Transplant Congress

    Safety and Efficacy of Early Central Line Removal in Post Liver Transplant Patients

    T. Shamaa1, E. MacLean1, O. Shamaa2, Z. Lu1, A. Hinge3, S. Saymuah3, A. Mohamed4, T. Kitajima4, S. Nagai4, M. Rizzari4, A. Yoshida4, M. Abouljoud4, K. Collins4

    1General Surgery, Henry Ford Hospital, Detroit, MI, 2Internal Medicine, Henry Ford Hospital, Detroit, MI, 3Wayne State University School of Medicine, Detroit, MI, 4Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Avoiding central line-associated infections (CLABSIs) is paramount in liver transplant recipients. As a hospital-wide infection control initiative at our institution, early removal of central…
  • 2022 American Transplant Congress

    Lung Transplant Recipients with Sars-cov2 Infection and Bnt162b2 Vaccination Induce Circulating Exosomes with Spike Protein S2 Capable of Inducing Immune Responses to Sars0-cov2 in Mice

    S. Bansal1, B. Tiffany1, T. Fleming1, S. Perincheri2, M. Smith1, R. Bremner1, T. Mohanakumar1

    1St. Joseph’s Hospital and Medical Center, Phoenix, AZ, 2Yale School of Medicine, New Haven, CT

    *Purpose: Exosomes are small vesicles which are released by cells into body fluids. We have demonstrated the presence of circulating exosomes with viral antigens in…
  • 2022 American Transplant Congress

    Evaluation of Prophylactic Valganciclovir Dosing in Kidney Transplant Recipients at an Urban Transplant Institution

    E. Foster1, D. Pierce1, T. Cairns1, S. Borgetti2, I. Tzvetanov3, E. Benedetti3, C. Muran1

    1Pharmacy, University of Illinois at Chicago, Chicago, IL, 2Medicine, University of Illinois at Chicago, Chicago, IL, 3Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Dosing and duration of cytomegalovirus (CMV) prophylaxis with valganciclovir (VGC) in kidney transplant (KT) recipients is variable by transplant center. Prior studies have shown…
  • 2022 American Transplant Congress

    Outcome of Heart Transplantation After Pseudomonas Left Ventricular Assist Device Infection

    L. Thirunavukarasu Murugan1, C. Koval2, J. Banzon3

    1Infectious Disease, Cleveland Clinic, Cleveland, OH, 2Cleveland Clinic Foundation, Cleveland, OH, 3Cleveland Clinic, Cleveland, OH

    *Purpose: Pseudomonas aeruginosa (PA) is the most common gram-negative bacteria to cause left ventricular assist device (LVAD) infection. Management is difficult given limited oral antibiotic…
  • 2022 American Transplant Congress

    Noroviral Diarrhea in Solid Organ Transplant Recipients: Characteristics, Interventions and Outcomes

    S. N. Nair, A. Bhaskaran, A. Chandorkar, L. Fontana, K. Obeid

    University of Minnesota, Minneapolis, MN

    *Purpose: Norovirus may result in significant morbidity in solid organ transplant (SOT) recipients. There is limited evidence for therapeutics beyond supportive care for the management…
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