ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2017 American Transplant Congress

    Conversion from Twice Daily to Once Daily Tacrolimus Improves Adherence in Kidney Transplant Recipients.

    M. Levine,1 K. Wen.2

    1Division of Urology, University of Alberta, Edmonton, AB, Canada; 2Department of Nephrology, University of Alberta, Edmonton, AB, Canada

    INTRODUCITON AND OBJECTIVE: Kidney transplant longevity is largely related to immunosuppressive efficacy, which is highly dependent on patient adherence. Drug dosing frequency is one way…
  • 2017 American Transplant Congress

    Anti-CD25mAb Sparing Immunosuppressive Regimen Suppressed Recurrence of Post-Transplant Focal Segmental Glomerular Sclerosis- A Single Center Experience.

    H. Harada, Y. Wada, N. Fukuzawa.

    Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan

    INTRODUCTION: The rate of recurrence of primary focal segmental glomerular sclerosis (FSGS) is problematic, because it often results in very early serious urinary protein secretion…
  • 2017 American Transplant Congress

    Lipid Abnormalities and Cardiovascular Events After Early Conversion to Everolimus in Kidney Transplant Recipients with Pretransplant Diabetes: 24-Month Analysis from Elevate Study.

    M. van der Giet,1 J. de Fijter,1 F. Oppenheimer,1 G. Russ,1 P. Lopez,2 G. Bader,2 J. Cruzado,1 H. Holdaas.1

    1ELEVATE Study Group, Berlin, Germany; 2Novartis Pharma AG, Basel, Switzerland

    PURPOSE: Pretransplant (preTx) diabetes is an independent risk factor for cardiovascular (CV) events, and posttransplant (post-Tx) hyperlipidemia further increases CV risk. To analyze the influence…
  • 2017 American Transplant Congress

    Steroid-Free Immunosuppression After Liver Transplant for Autoimmune Disease Does Not Result in Increased Disease Recurrence.

    A. Hooper,1 C. Frenette.2

    1Internal Medicine, Scripps Mercy Hospital, San Diego, CA; 2Organ Transplant, Scripps Green Hospital, La Jolla, CA

    Immunosuppression regimens in patients with end stage liver disease (ESLD) from autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) typically include…
  • 2017 American Transplant Congress

    De Novo Low-Dose Sirolimus versus Mycophenolate Mofetil in Combination with Extended-Release Tacrolimus in Kidney Transplant Recipients.

    J. Lee,1 K. Huh,1 J. Ha,2 C.-K. Oh,3 M. Ju,4 C.-D. Kim,5 H. Cho,6 C. Jung,7 B. Lim,8 Y. Kim.1

    1Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 2Surgery, Seoul National University Hospital, Seoul, Republic of Korea; 3Surgery, Ajou University Hospital, Suwon, Republic of Korea; 4Surgery, Gangnam Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 5Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea; 6Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 7Surgery, Korea University Anam Hospital, Seoul, Republic of Korea; 8Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea

    Previous studies reported that tacrolimus (TAC) with high-dose sirolimus (SRL) was associated with worse outcomes in kidney transplantation, compared to TAC with mycophenolate mofetil (MMF.).…
  • 2017 American Transplant Congress

    Resumption of Standard Dose Immunosuppression Following Resolution of BK Viremia Does Not Lead to Viremia Recurrence.

    K. Alquadan, A. Santos, M. Casey, T. Ozrazgat-Baslanti, S. Bozorgmehri, J. Gregg, K. Womer.

    Medicine, Nephrology, University of Florida, Gainesville, FL

    Introduction: Reduction of immunosuppression (IS) in response to BK viremia following kidney transplantation prevents the development of BK virus nephropathy, with no apparent increase in…
  • 2017 American Transplant Congress

    Long-Term Drug-Free Survival of Tiny Cynomolgus Islet Allografts.

    M. Koulmanda, V. Chipashivili, M. Duggan, T. Strom.

    Surgery and Medicine, Beth Israel Deaconess Medical Center, Boston, MA; Surgery, Massachusetts General Hospital, Boston, MA

    Following upon highly beneficial effects observed with short-term alpha 1-antitrypsin (AAT) treatment in the marginally sized autologous cynomolgus islet transplant model, we are testing the…
  • 2017 American Transplant Congress

    Successful Launch of an ABO-Incompatible Kidney Transplantation Program to Overcome the Shortage of Compatible Living Donors: Experience at a Single Center.

    S. Song,1 J. Lee,1 J. Lee,1 S.-K. Kwon,1 B. Kim,2,3 J. Lee,1 Y. Kim,1,3 M. Kim,1,3 S. Kim,1,3 K. Huh.1,3

    1Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Nephrology, Yonsei University Health System, Seoul, Republic of Korea; 3The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction:ABO-incompatible (ABOi) kidney transplantation (KT) is being increasingly performed to overcome donor shortages. However, debate persists regarding the post-transplant outcomes of ABOi KT versus that…
  • 2017 American Transplant Congress

    Antiretroviral Therapy Modification of HIV+ Patients Listed for Kidney Transplantation.

    D. Lee,1 G. Malat,3 T. Bias,1 S. Epstein,1 L. Levin Mizrahi,2 M. Harhay,2 S. Talluri,2 K. Ranganna.2

    1Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia; 2Division of Nephrology, Drexel University College of Medicine, Philadelphia; 3Department of Surgery, Drexel University College of Medicine, Philadelphia

    Introduction:HIV+ individuals can receive kidney transplant (KT) safely and effectively but face additional challenges from potential drug interactions between antiretroviral therapy (ART) and immunosuppression(IS). Little…
  • 2017 American Transplant Congress

    Immunosuppressant Costs for Medicare Part D and Kidney Transplant Recipients Since the Introduction of Generic Formulations in an Incident Kidney Transplant Population.

    M. Helmuth,1 M. Turenne,1 J. Park,2 Q. Liu,1 M. Oguntimein,3 S. Dutcher,3 R. Balkrishnan,4 J. Zee,1 A. Smith,1 A. Leichtman.1

    1Arbor Research Collaborative for Health, Ann Arbor, MI; 2U of Michigan, Ann Arbor, MI; 3Food and Drug Administration, Silver Spring, MD; 4U of Virginia, Charlottesville, VA

    Background: Substitution of generics (GEN) for brand name (BN) immunosuppressants (IS) has increased in kidney transplant recipients (KTR) since the introduction of GEN mycophenolate mofetil…
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