ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Immunosuppression"

  • 2017 American Transplant Congress

    De Novo Low-Dose Sirolimus versus Mycophenolate Mofetil in Combination with Extended-Release Tacrolimus in Kidney Transplant Recipients.

    J. Lee,1 K. Huh,1 J. Ha,2 C.-K. Oh,3 M. Ju,4 C.-D. Kim,5 H. Cho,6 C. Jung,7 B. Lim,8 Y. Kim.1

    1Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 2Surgery, Seoul National University Hospital, Seoul, Republic of Korea; 3Surgery, Ajou University Hospital, Suwon, Republic of Korea; 4Surgery, Gangnam Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 5Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea; 6Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 7Surgery, Korea University Anam Hospital, Seoul, Republic of Korea; 8Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea

    Previous studies reported that tacrolimus (TAC) with high-dose sirolimus (SRL) was associated with worse outcomes in kidney transplantation, compared to TAC with mycophenolate mofetil (MMF.).…
  • 2017 American Transplant Congress

    Resumption of Standard Dose Immunosuppression Following Resolution of BK Viremia Does Not Lead to Viremia Recurrence.

    K. Alquadan, A. Santos, M. Casey, T. Ozrazgat-Baslanti, S. Bozorgmehri, J. Gregg, K. Womer.

    Medicine, Nephrology, University of Florida, Gainesville, FL

    Introduction: Reduction of immunosuppression (IS) in response to BK viremia following kidney transplantation prevents the development of BK virus nephropathy, with no apparent increase in…
  • 2017 American Transplant Congress

    Long-Term Drug-Free Survival of Tiny Cynomolgus Islet Allografts.

    M. Koulmanda, V. Chipashivili, M. Duggan, T. Strom.

    Surgery and Medicine, Beth Israel Deaconess Medical Center, Boston, MA; Surgery, Massachusetts General Hospital, Boston, MA

    Following upon highly beneficial effects observed with short-term alpha 1-antitrypsin (AAT) treatment in the marginally sized autologous cynomolgus islet transplant model, we are testing the…
  • 2017 American Transplant Congress

    Successful Launch of an ABO-Incompatible Kidney Transplantation Program to Overcome the Shortage of Compatible Living Donors: Experience at a Single Center.

    S. Song,1 J. Lee,1 J. Lee,1 S.-K. Kwon,1 B. Kim,2,3 J. Lee,1 Y. Kim,1,3 M. Kim,1,3 S. Kim,1,3 K. Huh.1,3

    1Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Nephrology, Yonsei University Health System, Seoul, Republic of Korea; 3The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction:ABO-incompatible (ABOi) kidney transplantation (KT) is being increasingly performed to overcome donor shortages. However, debate persists regarding the post-transplant outcomes of ABOi KT versus that…
  • 2017 American Transplant Congress

    Antiretroviral Therapy Modification of HIV+ Patients Listed for Kidney Transplantation.

    D. Lee,1 G. Malat,3 T. Bias,1 S. Epstein,1 L. Levin Mizrahi,2 M. Harhay,2 S. Talluri,2 K. Ranganna.2

    1Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia; 2Division of Nephrology, Drexel University College of Medicine, Philadelphia; 3Department of Surgery, Drexel University College of Medicine, Philadelphia

    Introduction:HIV+ individuals can receive kidney transplant (KT) safely and effectively but face additional challenges from potential drug interactions between antiretroviral therapy (ART) and immunosuppression(IS). Little…
  • 2017 American Transplant Congress

    Immunosuppressant Costs for Medicare Part D and Kidney Transplant Recipients Since the Introduction of Generic Formulations in an Incident Kidney Transplant Population.

    M. Helmuth,1 M. Turenne,1 J. Park,2 Q. Liu,1 M. Oguntimein,3 S. Dutcher,3 R. Balkrishnan,4 J. Zee,1 A. Smith,1 A. Leichtman.1

    1Arbor Research Collaborative for Health, Ann Arbor, MI; 2U of Michigan, Ann Arbor, MI; 3Food and Drug Administration, Silver Spring, MD; 4U of Virginia, Charlottesville, VA

    Background: Substitution of generics (GEN) for brand name (BN) immunosuppressants (IS) has increased in kidney transplant recipients (KTR) since the introduction of GEN mycophenolate mofetil…
  • 2017 American Transplant Congress

    Systemic Immunosuppression in the Setting of Ocular Surface Stem Cell Transplantation.

    A. Govil,1 A. Cheung,2 E. Sarnicola,2 E. Holland.2

    1University of Cincinnati, Cincinnati, OH; 2Cincinnati Eye Institute, Cincinnati, OH

    Purpose: To evaluate the success, tolerability, and side effects of systemic immunosuppression (SI) in patients undergoing ocular surface stem cell transplantation (OSST) under the SI…
  • 2017 American Transplant Congress

    Medication Adherence and Medicare B Coverage Among Transplant Recipients.

    S. Boghani, H. Kirkham, Z. Berry, M. Kang.

    Walgreen Co., Deerfield, IL

    Purpose: Impact of nonadherence among transplant recipients has been well documented as a significant contributor of allograft failure. Medicare covers immunosuppressive medications for eligible patients…
  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    More Than Renal Function: Use of Belatacept to Improve Drug Toxicities.

    E. Cohen,1 B. Knight,3 W. Asch.2

    1Department of Pharmacy, Yale-New Haven Hospital, New Haven, CT; 2Department of Nephrology, Yale University, New Haven, CT; 3UCONN School of Pharmacy, Storrs, CT

    Background: Data with belatacept has demonstrated that patients on de novo belatacept have better renal function and improved patient and graft survival seven years post-transplant.…
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