2017 American Transplant Congress
Inhibition of Liver Natural Killer Cells Activation Through Co-Transplantation of Pre-Activated Mesenchymal Stem Cells Contributes to Improvement of Islet Graft Survival.
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
Introduction: We have previously reported that enhancement of TNF-related apoptosis-inducing ligand (TRAIL)-mediated liver NK-cell activity after intraportal islet transplantation (IT) inhibits engraftment of islets. Recently,…2017 American Transplant Congress
Kidney-Specific Immunosuppression without Adverse Systemic Effects.
Purpose: Immunosuppressive therapy is often accompanied by severe adverse effects. To overcome this, the aim of this study was the evaluation of a kidney-specific drug…2017 American Transplant Congress
Emerging Variables Which May Enhance Care of HIV Positive Renal Transplant Recipients.
Transplantation, Mayo Clinic, Jacksonville, FL
Purpose: Single center experience of kidney and pancreas transplantation in the HIV positive populationMethods: Retrospective data and outcomes analysis of HIV positive kidney and pancreas…2017 American Transplant Congress
Treatment of Post-Transplant Nephrotic Syndrome with Adrenocorticotropic (ACTH) Gel.
1Medstar Georgetown Transplant Institute, Washington DC; 2Indiana University Health, Indianapolis
Objectives: Post-kidney transplant proteinuria due to recurrent GN is considered to be a significant risk factor negatively affecting kidney transplant survival. In this case series…2017 American Transplant Congress
CD4+/CD8+ T Cell Ratio as a Predictive Marker for Early Graft Failure in Pig to Non-Human Primate Islet Xenotransplantation with Immunosuppression.
Background: Outstanding results from nonhuman primate study put islet xenotransplantation with immunosuppression closer to the clinical application. To establish successful immune suppressive protocols, immune monitoring…2017 American Transplant Congress
Predictors of Malignancies Across Solid Organ Transplantation.
Background & Aims:Solid organ transplant recipients are at much higher risk of cancer as compared to the general population. The aim of this study was…2017 American Transplant Congress
Prevalence of CYP3A Genomic Variances and Impact on Tacrolimus Dosing Requirements in Kidney Transplant Recipients in Eastern North Carolina.
1Vidant Medical Center, Greenville, NC; 2East Carolina University, Greenville, NC
BACKGROUND: African American (AA) patients are substantially more likely to express CYP3A5. Presence of CYP3A5 polymorphisms is an important pharmacotherapeutic consideration due to the extensive…2017 American Transplant Congress
Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.
Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…2017 American Transplant Congress
Everolimus Reduces Carotid Intima-Media Thickness in Renal Transplant Recipients After One Year: Randomized Controlled Trial.
Cardiovascular disease remains the commonest cause of death in kidney transplant recipients. Although some studies suggest that Mammalian target of rapamycin (mTOR) inhibitors may reduce…2017 American Transplant Congress
The Impact of Tacrolimus and MPA Derivative Immunosuppression on Acheived GFR in Recipients without Rejection: A Comparison of GFR of Living Donor Recipient Pairs at Six Months Post-Transplant.
Medicine, Division of Nephrology, Sacred Heart Hospital, Pensacola, FL
Analysis of the difference in estimated GFR (eGFR) of living donor recipient pairs at six months post-transplant showed that increased use of tacrolimus and MPA…
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