2018 American Transplant Congress
Elevated Levels of CD19+ B Cells before or after Rituximab Administration is a Risk Factor for the Early Rejection of a Living Kidney Transplant
1Nephrology, Ohkubo Hospital, Tokyo, Japan; 2Urology, Ohkubo Hospital, Tokyo, Japan.
[Introduction]Rituximab (RTX) is used for desensitization in highly sensitized patients, such as those undergoing ABO-incompatible (ABOi) kidney transplantation. Although RTX is generally effective, some patients…2018 American Transplant Congress
Ideal Body Weight versus Actual Body Weight for Rabbit Antithymocyte Globulin Induction in Pancreas Transplantation
Purpose: Rabbit antithymocyte globulin (rATG) is the most commonly used induction agent in solid organ pancreas transplantation. The optimal induction dosing of rATG, has not…2018 American Transplant Congress
Outcomes Associated with Rabbit Anti-Thymocyte Globulin Induction According to Mg/Kg of Total Body Weight in Kidney Transplant Recipients
Pharmacy, Tampa General Hospital, Tampa, FL.
Purpose: The optimal dosing weight used for rabbit anti-thymocyte globulin (rATG) induction therapy in transplantation continues to lack a consensus. The impact of alternative dosing…2018 American Transplant Congress
The Impact of Rapamycin Conversion in Pediatric Liver Transplantation on Anti-HLA Antibody Formation and Allograft Fibrosis
Background: Maintenance immunosuppression with tacrolimus (TAC) is associated with progressive liver allograft fibrosis. Conversion to rapamycin (RAPA) may abrogate this progression. The development of donor-specific…2018 American Transplant Congress
Once-Daily MeltDose Tacrolimus Formulation and Renal Function in Caucasian Fast Tacrolimus Metabolizers: Does Early Identification Have an Impact in PK Sensitive Patients?
Tacrolimus (TAC) nephrotoxicity can be seen even at low blood trough levels, with factors beyond trough levels potentially contributing. TAC fast metabolizers have higher Cmax,…2018 American Transplant Congress
Development of Optimal Simplified Equation for Estimation of Mycophenolic Acid Exposure Following Enteric-Coated Mycophenolate Sodium Administration in Chinese Renal Transplant Recipients
MyERA Study Group, Hangzhou, China.
Background: Limited sampling strategies (LSS) aids in overcoming the complexity of extensive PK sampling and supporting the calculation of mycophenolic acid (MPA) exposure. This study…2018 American Transplant Congress
Effects of Medication Education Pilot Program in Living versus Deceased Donor Kidney Transplant Recipients.
Henry Ford Transplant Institute, Detroit, MI.
Purpose: Medication adherence is crucial for transplant recipients as non-adherence can result in increased risk of rejection and graft loss. Early education prior to transplant…2018 American Transplant Congress
Activation Requirements of Costimulation Blockade-Resistant CD4 T Cells
T cells lose costimulation dependence following primary activation and many phenotypes of terminally differentiated cells have been identified as contributing to costimulation blockade (CoB)-resistant rejection…2018 American Transplant Congress
Improvement in Intermediate Graft Survival among Deceased Donor Recipients in the Last Decade Due to Improvements in Outcomes of Higher KDPI Kidney Recipients
Medicine, Sacred Heart Hospital, Pensacola, FL, Turkey.
Previous research by our group showed that intermediate graft survival of adult deceased donor kidney transplants between six months and three years post-transplant improved in…2017 American Transplant Congress
Mycophenolate Dose Reductions Are Not Associated with De Novo Donor-Specific Antibodies.
University of Colorado, Aurora, CO
De novo donor-specific antibodies (dnDSA) are central to the development of antibody-mediated rejection, which is the most important cause of death-censored graft loss. It is…
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