2018 American Transplant Congress
Can We Optimise Immunosuppression Strategies in Our Older Renal Transplant Recipients?
Renal transplantation provides a survival advantage for patients including those with multiple co-morbidities and older age compared to remaining on dialysis. The optimal immunosuppressive regime…2018 American Transplant Congress
De Novo Use of Extended Released Tacrolimus (Meltdose, EnvasusR)) after OLT – Does the Colonic Resorption Influences the Outcome?
Department of Transplantation, Medical University of Vienna, Vienna, Austria.
Introduction: Immunosuppression after OLT has reached a quite high standard with an excellent evidence base. However, there is still a lack of data for the…2018 American Transplant Congress
The Clinical Efficacy of Seasonal Influenza Vaccination – Characteristics of Two Outbreaks of Influenza A(H1N1) in Immunocompromised Patients
A. Background. Influenza A(H1N1) causes serious complications in immunocompromised patients. The efficacy of seasonal influenza vaccination in transplant recipients and patients receiving chemotherapy has been…2018 American Transplant Congress
Outcomes in Liver Transplant Patients on Renal Sparing Protocol
As liver transplant outcomes have improved, long term native kidney function has taken a critical role in patient survival. Calcineurin inhibitors (CNIs), such as Tacrolimus…2018 American Transplant Congress
Belatacept in Kidney Transplant Recipients with Preformed Donor Specific Anti-HLA Antibodies: Results of the BELACOR Trial
IntroductionAntibody-mediated rejection (ABMR) is currently a critical question in kidney transplant recipient with immunological risk factors such as pre transplant donor-specific anti HLA antibodies (DSA).…2018 American Transplant Congress
Identification of Anti-Inflammatory and Pro-Inflammatory Gut Microbiota That Determine Graft Survival
Introduction: The gut microbiota induce and train the host immune system. Whether microbiota from contrasting environments of colitic or pregnant mice are pro- or anti-inflammatory…2018 American Transplant Congress
Superior Renal Function with CNI-Free Everolimus over Standard CNI-Based Regimen: 18 Months Data from the Randomized, Multi-Center MANDELA Trial in De Novo Heart Transplant Recipients
1Mandela Study Group, Germany; 2Novartis, Pharma, Germany.
Purpose: The MANDELA study (NCT00862979) was designed to assess the benefit on renal function of either CNI-free or CNI-minimized EVR-based regimen after early conversion of…2018 American Transplant Congress
Association of Tacrolimus Adherence and Discontinuation with Sepsis Risk among Kidney Transplant Recipients
OBJECTIVE: The association between post-transplant tacrolimus exposure and sepsis risk is currently unknown. We examined the associations of tacrolimus adherence and discontinuation with sepsis risk…2018 American Transplant Congress
Human CD8+CD28– Ts Cells Expanded by Common Gamma Chain (γc) Cytokines Keep Steady Allospecific Suppressive Capacity In Vivo
Background: CD8+CD28- T suppressor (Ts) cells were recently reported to play a critical role in transplant tolerance, harnessing the potential for clinical use in transplantation.…2018 American Transplant Congress
Risk of Bacteremia According to Transplant Induction Immunosuppression Regimen
University of Wisconsin School of Medicine and Public Health, Madison.
Background: Transplant immune suppression is designed to suppress the adaptive immune response and ensure graft survival, but may have unintended effects on innate immunity. Few…
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